Nicolas A Menzies

Dados Biográficos

ID6330567
NOMENicolas A Menzies
PRENOMESNicolas A
SOBRENOMEMenzies
ASSINATURAMENZIES N A
AFILIAÇÕESHarvard Global Health Institute
ORCID0000-0002-2571-016X
VERIFICADOSim
TOTAL DE OBRAS18
TOTAL DE CITAÇÕES3
TOTAL COMO AUTOR18
TOTAL COMO EDITOR0
PRIMEIRO ANO DE PUBLICAÇÃO2016
ANO MAIS RECENTE DE PUBLICAÇÃO2026
ÍNDICE H1

  • Prenatal Syphilis Screening Mandates and Maternal Syphilis Case Detection

    Open AccessSarah E Baum, Leila Agha et al.ARTICLEJAMA Health Forum2026

    In this study, expanded prenatal syphilis screening mandates may improve syphilis case detection in the near-term but are unlikely to have sustained impact without complementary efforts, such as those that facilitate clinician adherence and ensure patient access to and completion of treatment

  • Systematic differences in TB treatment outcomes across Brazil by patient- and area-related factors

    Open AccessDo Kyung Ryuk, Daniele Maria Pelissari et al.ARTICLEBMJ Global Health2025

    BACKGROUND: Many individuals initiating tuberculosis (TB) treatment do not successfully complete the regimen. Understanding variation in treatment outcomes could reveal opportunities to improve the effectiveness of TB treatment services. METHODS: We extracted data on treatment outcomes and patient covariates from Brazil's National Disease Notification Information System, for new TB patients diagnosed during 2015-2018. We analysed whether or not p…

  • Low-dose calcium supplementation during pregnancy in low and middle-income countries

    Open AccessHappiness Pius Saronga, Pratibha Dwarkanath et al.ARTICLEPLOS Global Public Health2025

    Calcium supplementation during pregnancy can reduce the risk of preeclampsia and preterm birth. Few countries have implemented WHO-recommended high-dose calcium supplementation (1500–2000mg/day), due to adherence and cost concerns. However, low-dose calcium supplementation (one 500mg tablet daily) has recently been shown to be similarly efficacious as high-dose supplementation. We assessed the cost-effectiveness of low-dose calcium supplementatio…

  • Distribution and transmission of M. tuberculosis in a high-HIV prevalence city in Malawi

    Open AccessMelanie H Chitwood, Elizabeth L Corbett et al.ARTICLEPLOS Global Public Health2025

    Delays in identifying and treating individuals with infectious tuberculosis (TB) contribute to poor health outcomes and allow ongoing community transmission of M. tuberculosis ( Mtb ). Current recommendations for screening for tuberculosis specify community characteristics (e.g., areas with high local tuberculosis prevalence) that can be used to target screening within the general population. However, areas of higher tuberculosis burden are not n…

  • Uncertainty in tuberculosis clinical decision-making

    Open AccessFrancesca Wanda Basile, Stuart Sweeney et al.ARTICLEPLOS Global Public Health2024

    Tuberculosis is a major infectious disease worldwide, but currently available diagnostics have suboptimal accuracy, particularly in patients unable to expectorate, and are often unavailable at the point-of-care in resource-limited settings. Test/treatment decision are, therefore, often made on clinical grounds. We hypothesized that contextual factors beyond disease probability may influence clinical decisions about when to test and when to treat …

  • Health impact and cost-effectiveness of expanding routine immunization coverage in India through Intensified Mission Indradhanush

    Open AccessEmma Clarke-Deelder, Christian Suharlim et al.ARTICLEHealth Policy and Planning2024

    Many children do not receive a full schedule of childhood vaccines, yet there is limited evidence on the cost-effectiveness of strategies for improving vaccination coverage. Evidence is even scarcer on the cost-effectiveness of strategies for reaching ‘zero-dose children’, who have not received any routine vaccines. We evaluated the cost-effectiveness of periodic intensification of routine immunization (PIRI), a widely applied strategy for increa…

  • Associations Between Alcohol Use, Antiretroviral Therapy Use, and Viral Load Suppression Among People Living with HIV in Rural Central Uganda

    Open AccessAdriane Wynn, Katelyn M Sileo et al.ARTICLEAIDS and Behavior2024

    Alcohol use among people living with HIV (PWH) is common and may negatively affect engagement in HIV care. We evaluated the relationships between alcohol use, ART use, and viral suppression among PWH in Uganda. PATH/Ekkubo was a trial evaluating a linkage to HIV care intervention in four Ugandan districts, Nov 2015-Sept 2021. Our analytical sample included: (1) baseline data from individuals not enrolled in the intervention trial (previously diag…

  • The potential impact of novel tuberculosis vaccines on health equity and financial protection in low-income and middle-income countries

    Open AccessAllison Portnoy, Rebecca A Clark et al.ARTICLEBMJ Global Health2023

    INTRODUCTION: One in two patients developing tuberculosis (TB) in low-income and middle-income countries (LMICs) faces catastrophic household costs. We assessed the potential financial risk protection from introducing novel TB vaccines, and how health and economic benefits would be distributed across income quintiles. METHODS: We modelled the impact of introducing TB vaccines meeting the World Health Organization preferred product characteristics…

  • Quality of care for postpartum hemorrhage

    Open AccessEmma Clarke-Deelder, Kennedy Opondo et al.ARTICLEPLOS Global Public Health2023

    Postpartum hemorrhage (PPH) is the leading cause of maternal mortality in Kenya. The aim of this study was to measure quality and timeliness of care for PPH in a sample of deliveries in referral hospitals in Kenya. We conducted direct observations of 907 vaginal deliveries in three Kenyan hospitals from October 2018 through February 2019, observing the care women received from admission for labor and delivery through hospital discharge. We identi…

  • Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition

    Open AccessNicolas A Menzies, Fatou Berthé et al.ARTICLEPLOS Global Public Health2022

    Severe acute malnutrition (SAM) is a major source of mortality for children in low resource settings. Alternative treatment models that improve acceptability and reduce caregiver burden are needed to improve treatment access. We assessed costs and cost-effectiveness of monthly vs. weekly follow-up (standard-of-care) for treating uncomplicated SAM in children 6–59 months of age. To do so, we conducted a cost-effectiveness analysis of a cluster-ran…

  • A spatial-mechanistic model to estimate subnational tuberculosis burden with routinely collected data

    Open AccessMelanie H Chitwood, Layana Costa Alves et al.ARTICLEPLOS Global Public Health2022

    Reliable subnational estimates of TB incidence would allow national policy makers to focus disease control resources in areas of highest need. We developed an approach for generating small area estimates of TB incidence, and the fraction of individuals missed by routine case detection, based on available notification and mortality data. We demonstrate the feasibility of this approach by creating municipality-level burden estimates for Brazil. We …

  • Cost-effectiveness of zinc supplementation for prevention of childhood diarrhoea in Tanzania

    Open AccessHappiness Pius Saronga, Karim Manji et al.ARTICLEPublic Health Nutrition2022

    Objective: To assess the cost-effectiveness of prophylactic Zn supplementation for preventing diarrhoea in young children in Tanzania. Design: Cost-effectiveness analysis using decision-analytic modelling. Cost-effectiveness ratios were calculated as the incremental cost (2019 USD) per disability-adjusted life year (DALY) averted, from a societal perspective, and with a 3 % discount rate applied to future outcomes. Sensitivity analyses were perfo…

  • Impact of campaign-style delivery of routine vaccines

    Open AccessEmma Clarke-Deelder, Christian Suharlim et al.ARTICLEHealth Policy and Planning2021

    The world is not on track to achieve the goals for immunization coverage and equity described by the World Health Organization’s Global Vaccine Action Plan. Many countries struggle to increase coverage of routine vaccination, and there is little evidence about how to do so effectively. In India in 2016, only 62% of children had received a full course of basic vaccines. In response, in 2017–18 the government implemented Intensified Mission Indradh…

  • Targeting screening and treatment for latent tuberculosis infection towards asylum seekers from high-incidence countries – a model-based cost-effectiveness analysis

    Open AccessFlorian M Marx, Barbara Hauer et al.ARTICLEBMC Public Health2021

    LTBI screening and TPT among 15- to 34-year-old asylum seekers arriving in Germany could produce health benefits at reasonable additional cost (with respect to international benchmarks) if introduced at incidence thresholds ≥100. Empirical trials are needed to investigate the feasibility and effectiveness of this approach

  • Mathematical modeling study of school-based chlamydia screening

    Open AccessMinttu M Rönn, Richard Dunville et al.ARTICLEBMC Public Health2020

    Sustained high student participation in school-based screening programs and broad coverage of schools within a target community are likely needed to maximize program benefits in terms of reduced burden of chlamydia in the adolescent population

  • Incorporating costing study results into district and service planning to enhance immunization programme performance

    Open AccessIsabelle Feldhaus, Carl Schütte et al.ARTICLEHealth Policy and Planning2019Citada por: 1Referências: 31

    Donors, researchers and international agencies have made significant investments in collection of high-quality data on immunization costs, aiming to improve the efficiency and sustainability of services. However, improved quality and routine dissemination of costing information to local managers may not lead to enhanced programme performance. This study explored how district- and service-level managers can use costing information to enhance plann…

  • The cost structure of routine infant immunization services

    Open AccessFangli Geng, Christian Suharlim et al.ARTICLEHealth Policy and Planning2017Citada por: 2Referências: 20

    Little information exists on the cost structure of routine infant immunization services in low- and middle-income settings. Using a unique dataset of routine infant immunization costs from six countries, we estimated how costs were distributed across budget categories and programmatic activities, and investigated how the cost structure of immunization sites varied by country and site characteristics. The EPIC study collected data on routine infan…

  • Cost analysis of the treatment of severe acute malnutrition in West Africa

    Open AccessSheila Isanaka, Nicolas A Menzies et al.ARTICLEMaternal and Child Nutrition2016

    We present an updated cost analysis to provide new estimates of the cost of providing community-based treatment for severe acute malnutrition, including expenditure shares for major cost categories. We calculated total and per child costs from a provider perspective. We categorized costs into three main activities (outpatient treatment, inpatient treatment, and management/administration) and four cost categories within each activity (personnel; t…