Brian C Zanoni
Dados Biográficos
| ID | 6806912 |
|---|---|
| NOME | Brian C Zanoni |
| PRENOMES | Brian C |
| SOBRENOME | Zanoni |
| ASSINATURA | ZANONI B C |
| AFILIAÇÕES | Emory University |
| ORCID | 0000-0002-8640-7703 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 25 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2006 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 0 |
Preferred characteristics of long-acting injectable antiretroviral treatment for adolescents with HIV in KwaZulu-Natal, South Africa
The human cost of US foreign aid cuts
In early 2025, the abrupt suspension of U.S. foreign aid to South Africa - including funding from United States President's Emergency Plan for AIDS Relief (PEPFAR), the United States Agency for International Development (USAID), the Centers for Disease Control and Prevention (CDC), and the National Institutes of Health (NIH) - has triggered a multidimensional crisis in the country's HIV response. This paper synthesises emerging evidence on the hu…
“Now, I have no fear”
South Africa has the highest number of adolescents living with HIV (AHIV) globally, many of whom face disengagement and virologic failure when transitioning from pediatric to adult care. Using the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) and the Technology Acceptance Model (TAM), we evaluated the acceptability, feasibility, and perceived effectiveness of an in-person and virtual adolescent support inte…
Healthcare workers’ perspective about barriers and facilitators to pediatric HIV status disclosure in eastern Uganda using capability opportunity and motivation of behavior change model
HIV status disclosure by caregivers to children and adolescents living with HIV (CALH) remains a public health concern in countries with a high burden of HIV despite guidelines for healthcare workers (HCWs) to facilitate the process. This study explored barriers and facilitators to HIV disclosure at two referral hospitals in eastern Uganda focusing on the utilization of existing guidelines. In-depth qualitative interviews were conducted among all…
Can AI teach sex ed? A systematic review of the use of artificial intelligence in sexual and reproductive health education
Artificial intelligence (AI) is rapidly evolving in healthcare and education, including in sexual and reproductive health (SRH) education. AI tools may improve access to convenient, non-judgemental, and comprehensive SRH education for people of all genders, sexualities and ages. This systematic review used the Technology Acceptance Model to evaluate the acceptability, feasibility, and impact of AI-driven chatbots in SRH education. We searched Pub…
WhatsApp-based sexual and reproductive health education for adolescents with perinatally acquired HIV
Adolescents with perinatally-acquired HIV in South Africa have limited access to relevant sexual and reproductive health (SRH) education. Mobile health (mHealth) can discreetly deliver such education but has not been tested with members of this population. In this study, we describe the effects of an mHealth intervention to support transition to adult care-Interactive Transition Support for Adolescents with HIV (InTSHA)-on SRH attitudes. Between …
Lived experiences and coping mechanisms among children and adolescents living with HIV after HIV disclosure in Eastern Uganda
PURPOSE: To understand the experiences and coping mechanisms of children and adolescents living with HIV (CALH) after HIV disclosure. METHODS: We conducted a qualitative study among CALH after HIV disclosure receiving care from two referral hospitals in eastern Uganda. In-depth interviews were conducted using an interview guide during routine outpatient visits to HIV clinics until data saturation was achieved. All interviews were audiotaped, and …
Strengthening implementation science research to improve adolescent and young adult HIV-prevention and care in Sub-Saharan Africa
Not Applicable
Factor Structure, Reliability, and Validity of the 10-Item HIV Stigma Scale for Adolescents and Youth Living with HIV in Rural, Southwestern Uganda
A qualitative analysis of self-management needs of adolescents and young adults living with perinatally acquired HIV in rural, southwestern Uganda
The number of adolescents living with HIV remains high in sub-Saharan Africa with poorer HIV treatment outcomes among adolescents and young adults compared to individuals in other age groups. For adolescents and young adults living with perinatally acquired HIV (AYLPHIV), the transition from pediatric to adult HIV care is a particularly high-risk period. We conducted a qualitative study to understand self-management needs of AYLPHIV in rural, sou…
Acceptability, feasibility and preliminary effectiveness of the mHealth intervention, InTSHA, on retention in care and viral suppression among adolescents with HIV in South Africa
We describe the results of a pilot randomized clinical trial of a mobile phone-based intervention, InTSHA: Interactive Transition Support for Adolescents with HIV, compared to standard care. Encrypted, closed group chats delivered via WhatsApp provided peer support and improved communication between adolescents with HIV, their caregivers, and healthcare providers. We randomized 80 South African adolescents ages 15 to 19 years with perinatally-acq…
Addressing the Know-Do Gap in Adolescent HIV
Implementation science (IS) uses systematic methods to close gaps between research and practice by identifying and addressing barriers to implementation of evidence-based interventions (EBIs). To reach UNAIDS HIV targets, IS can support programs to reach vulnerable populations and achieve sustainability. We studied the application of IS methods in 36 study protocols that were part of the Adolescent HIV Prevention and Treatment Implementation Scie…
The ethical‐legal requirements for adolescent self‐consent to research in sub‐Saharan Africa
Support for the enrolment of adolescents in research has been constrained by uncertainties in parental involvement, and the lack of clarity in the ethical and legal frameworks. We conducted a scoping review to examine articles that explored the opinion of scholars on the question of adolescent consent and conditions for parental waivers in research in sub‐Saharan Africa (SSA). Guided by the Preferred Reporting Items for Systematic Reviews and Met…
Impact of Covid-19 on Adolescent HIV Prevention and Treatment Research in the Ahisa Network
Members of the Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA) network conduct research aiming to close gaps between what is known to be impactful across the HIV prevention and treatment cascade, and services delivered to optimize outcomes for adolescents/young adults (AYA) in high HIV-prevalence settings. The COVID-19 pandemic introduced new challenges which threaten to exacerbate care and access disparities. We r…
Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
We created a transition readiness score for adolescents with perinatally-acquired HIV as they transition from pediatric to adult care. Of the 199 adolescents who transitioned to adult care, 84 (42%) had viral suppression (< 200 copies/ml) one year after transition. Adolescents on first-line ART, with documented HIV status disclosure, and higher rating on the HIV Adolescent Readiness to Transition Scale had significantly higher odds of viral suppr…
Challenges and Fears of Adolescents and Young Adults Living with HIV Facing Transition to Adult HIV Care
Impact of Covid-19 on Adolescent HIV Prevention and Treatment Services in the Ahisa Network
We investigated perceived impacts of COVID-19 on the delivery of adolescent HIV treatment and prevention services in sub-Saharan Africa (SSA) by administering a survey to members of the Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA) from February to April 2021. We organized COVID-19 impacts, as perceived by AHISA teams, under three themes: service interruptions, service adjustments, and perceived individual-level …
Disseminating Evidence-Based Interventions for Adolescent HIV Treatment and Prevention in Sub-Saharan Africa
Over two-thirds of adolescents living with HIV worldwide reside in sub-Saharan Africa (SSA). Despite widespread availability and access to evidence-based HIV prevention and treatment, dissemination has been inadequate. This commentary distinguishes between implementation and dissemination, reflecting on the unique barriers to dissemination of evidence-based programs in SSA. We present a seven-strategy blueprint developed by United States Agency f…
It was not okay because you leave your friends behind’
Improved preparation for transition by pediatric and adult clinical staff, including restructuring of care delivery, may improve successful transition of adolescents living with perinatally acquired HIV to adult care. Transition readiness assessments are needed to determine optimal timing of transition and which adolescents are ready to transition to adult care
Disclosure, Social Support, and Mental Health are Modifiable Factors Affecting Engagement in Care of Perinatally-HIV Infected Adolescents
Prevalence of depressive symptoms and associated factors among adolescents living with HIV/Aids in South Western Uganda
Adolescents living with HIV (ALHIV) are prone to depression, which can have detrimental effects including disease progression, poor treatment adherence and mortality. We aimed to determine the prevalence of depressive symptoms and their associated factors among ALHIV in Uganda. We conducted a cross-sectional survey among ALHIV (10-19 years) attending urban and rural clinics in Mbarara, Uganda between March and May 2017. Presence of depressive sym…
Barriers to Retention in Care are Overcome by Adolescent-Friendly Services for Adolescents Living with HIV in South Africa
The Acceptability and Perceived Usefulness of a Weekly Clinical SMS Program to Promote HIV Antiretroviral Medication Adherence in KwaZulu-Natal, South Africa
The Adolescent and Young Adult HIV Cascade of Care in the United States
Little is known about how adolescents and young adults contribute to the declines in the cascade of care from HIV-1 diagnosis to viral suppression. We reviewed published literature from the Unites States reporting primary data for youth (13-29 years of age) at each stage of the HIV cascade of care. Approximately 41% of HIV-infected youth in the United States are aware of their diagnosis, while only 62% of those diagnosed engage medical care withi…
Caring Comportment and the Hospitalist Model
The hospitalist model of inpatient care is associated with cost-effective and high-quality care, but this result may come at the cost of patients’ own expressed values. Certain procedural changes can reemphasize patient values, but they must be accompanied by shifts in the comportment of hospitalists, whose current practices have the potential to undermine the model’s benefits
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Caring Comportment and the Hospitalist Model
The hospitalist model of inpatient care is associated with cost-effective and high-quality care, but this result may come at the cost of patients’ own expressed values. Certain procedural changes can reemphasize patient values, but they must be accompanied by shifts in the comportment of hospitalists, whose current practices have the potential to undermine the model’s benefits
The Adolescent and Young Adult HIV Cascade of Care in the United States
Little is known about how adolescents and young adults contribute to the declines in the cascade of care from HIV-1 diagnosis to viral suppression. We reviewed published literature from the Unites States reporting primary data for youth (13-29 years of age) at each stage of the HIV cascade of care. Approximately 41% of HIV-infected youth in the United States are aware of their diagnosis, while only 62% of those diagnosed engage medical care withi…
The Acceptability and Perceived Usefulness of a Weekly Clinical SMS Program to Promote HIV Antiretroviral Medication Adherence in KwaZulu-Natal, South Africa
Barriers to Retention in Care are Overcome by Adolescent-Friendly Services for Adolescents Living with HIV in South Africa
Prevalence of depressive symptoms and associated factors among adolescents living with HIV/Aids in South Western Uganda
Adolescents living with HIV (ALHIV) are prone to depression, which can have detrimental effects including disease progression, poor treatment adherence and mortality. We aimed to determine the prevalence of depressive symptoms and their associated factors among ALHIV in Uganda. We conducted a cross-sectional survey among ALHIV (10-19 years) attending urban and rural clinics in Mbarara, Uganda between March and May 2017. Presence of depressive sym…
Disclosure, Social Support, and Mental Health are Modifiable Factors Affecting Engagement in Care of Perinatally-HIV Infected Adolescents
It was not okay because you leave your friends behind’
Improved preparation for transition by pediatric and adult clinical staff, including restructuring of care delivery, may improve successful transition of adolescents living with perinatally acquired HIV to adult care. Transition readiness assessments are needed to determine optimal timing of transition and which adolescents are ready to transition to adult care
The ethical‐legal requirements for adolescent self‐consent to research in sub‐Saharan Africa
Support for the enrolment of adolescents in research has been constrained by uncertainties in parental involvement, and the lack of clarity in the ethical and legal frameworks. We conducted a scoping review to examine articles that explored the opinion of scholars on the question of adolescent consent and conditions for parental waivers in research in sub‐Saharan Africa (SSA). Guided by the Preferred Reporting Items for Systematic Reviews and Met…
Impact of Covid-19 on Adolescent HIV Prevention and Treatment Research in the Ahisa Network
Members of the Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA) network conduct research aiming to close gaps between what is known to be impactful across the HIV prevention and treatment cascade, and services delivered to optimize outcomes for adolescents/young adults (AYA) in high HIV-prevalence settings. The COVID-19 pandemic introduced new challenges which threaten to exacerbate care and access disparities. We r…
Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
We created a transition readiness score for adolescents with perinatally-acquired HIV as they transition from pediatric to adult care. Of the 199 adolescents who transitioned to adult care, 84 (42%) had viral suppression (< 200 copies/ml) one year after transition. Adolescents on first-line ART, with documented HIV status disclosure, and higher rating on the HIV Adolescent Readiness to Transition Scale had significantly higher odds of viral suppr…
Challenges and Fears of Adolescents and Young Adults Living with HIV Facing Transition to Adult HIV Care
Impact of Covid-19 on Adolescent HIV Prevention and Treatment Services in the Ahisa Network
We investigated perceived impacts of COVID-19 on the delivery of adolescent HIV treatment and prevention services in sub-Saharan Africa (SSA) by administering a survey to members of the Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA) from February to April 2021. We organized COVID-19 impacts, as perceived by AHISA teams, under three themes: service interruptions, service adjustments, and perceived individual-level …
Disseminating Evidence-Based Interventions for Adolescent HIV Treatment and Prevention in Sub-Saharan Africa
Over two-thirds of adolescents living with HIV worldwide reside in sub-Saharan Africa (SSA). Despite widespread availability and access to evidence-based HIV prevention and treatment, dissemination has been inadequate. This commentary distinguishes between implementation and dissemination, reflecting on the unique barriers to dissemination of evidence-based programs in SSA. We present a seven-strategy blueprint developed by United States Agency f…
Addressing the Know-Do Gap in Adolescent HIV
Implementation science (IS) uses systematic methods to close gaps between research and practice by identifying and addressing barriers to implementation of evidence-based interventions (EBIs). To reach UNAIDS HIV targets, IS can support programs to reach vulnerable populations and achieve sustainability. We studied the application of IS methods in 36 study protocols that were part of the Adolescent HIV Prevention and Treatment Implementation Scie…
A qualitative analysis of self-management needs of adolescents and young adults living with perinatally acquired HIV in rural, southwestern Uganda
The number of adolescents living with HIV remains high in sub-Saharan Africa with poorer HIV treatment outcomes among adolescents and young adults compared to individuals in other age groups. For adolescents and young adults living with perinatally acquired HIV (AYLPHIV), the transition from pediatric to adult HIV care is a particularly high-risk period. We conducted a qualitative study to understand self-management needs of AYLPHIV in rural, sou…
Acceptability, feasibility and preliminary effectiveness of the mHealth intervention, InTSHA, on retention in care and viral suppression among adolescents with HIV in South Africa
We describe the results of a pilot randomized clinical trial of a mobile phone-based intervention, InTSHA: Interactive Transition Support for Adolescents with HIV, compared to standard care. Encrypted, closed group chats delivered via WhatsApp provided peer support and improved communication between adolescents with HIV, their caregivers, and healthcare providers. We randomized 80 South African adolescents ages 15 to 19 years with perinatally-acq…
Healthcare workers’ perspective about barriers and facilitators to pediatric HIV status disclosure in eastern Uganda using capability opportunity and motivation of behavior change model
HIV status disclosure by caregivers to children and adolescents living with HIV (CALH) remains a public health concern in countries with a high burden of HIV despite guidelines for healthcare workers (HCWs) to facilitate the process. This study explored barriers and facilitators to HIV disclosure at two referral hospitals in eastern Uganda focusing on the utilization of existing guidelines. In-depth qualitative interviews were conducted among all…
Can AI teach sex ed? A systematic review of the use of artificial intelligence in sexual and reproductive health education
Artificial intelligence (AI) is rapidly evolving in healthcare and education, including in sexual and reproductive health (SRH) education. AI tools may improve access to convenient, non-judgemental, and comprehensive SRH education for people of all genders, sexualities and ages. This systematic review used the Technology Acceptance Model to evaluate the acceptability, feasibility, and impact of AI-driven chatbots in SRH education. We searched Pub…
WhatsApp-based sexual and reproductive health education for adolescents with perinatally acquired HIV
Adolescents with perinatally-acquired HIV in South Africa have limited access to relevant sexual and reproductive health (SRH) education. Mobile health (mHealth) can discreetly deliver such education but has not been tested with members of this population. In this study, we describe the effects of an mHealth intervention to support transition to adult care-Interactive Transition Support for Adolescents with HIV (InTSHA)-on SRH attitudes. Between …
Lived experiences and coping mechanisms among children and adolescents living with HIV after HIV disclosure in Eastern Uganda
PURPOSE: To understand the experiences and coping mechanisms of children and adolescents living with HIV (CALH) after HIV disclosure. METHODS: We conducted a qualitative study among CALH after HIV disclosure receiving care from two referral hospitals in eastern Uganda. In-depth interviews were conducted using an interview guide during routine outpatient visits to HIV clinics until data saturation was achieved. All interviews were audiotaped, and …
Strengthening implementation science research to improve adolescent and young adult HIV-prevention and care in Sub-Saharan Africa
Not Applicable
Factor Structure, Reliability, and Validity of the 10-Item HIV Stigma Scale for Adolescents and Youth Living with HIV in Rural, Southwestern Uganda
Preferred characteristics of long-acting injectable antiretroviral treatment for adolescents with HIV in KwaZulu-Natal, South Africa
The human cost of US foreign aid cuts
In early 2025, the abrupt suspension of U.S. foreign aid to South Africa - including funding from United States President's Emergency Plan for AIDS Relief (PEPFAR), the United States Agency for International Development (USAID), the Centers for Disease Control and Prevention (CDC), and the National Institutes of Health (NIH) - has triggered a multidimensional crisis in the country's HIV response. This paper synthesises emerging evidence on the hu…
“Now, I have no fear”
South Africa has the highest number of adolescents living with HIV (AHIV) globally, many of whom face disengagement and virologic failure when transitioning from pediatric to adult care. Using the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) and the Technology Acceptance Model (TAM), we evaluated the acceptability, feasibility, and perceived effectiveness of an in-person and virtual adolescent support inte…
HIV/AIDS Research and Interventions (20 obras) · Medicine (20 obras) · Nursing (15 obras) · Family medicine (14 obras) · Psychology (14 obras) · Adolescent Sexual and Reproductive Health (13 obras) · Public health (12 obras) · Adolescent and Pediatric Healthcare (10 obras) · Health psychology (10 obras) · Environmental health (8 obras)