Dariush Mozaffarian
Dados Biográficos
| ID | 703353 |
|---|---|
| NOME | Dariush Mozaffarian |
| PRENOMES | Dariush |
| SOBRENOME | Mozaffarian |
| ASSINATURA | MOZAFFARIAN D |
| AFILIAÇÕES | Tufts University |
| ORCID | 0000-0001-7958-9492 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 71 |
| TOTAL DE CITAÇÕES | 31 |
| TOTAL COMO AUTOR | 71 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2006 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 3 |
Why patients stay in or leave a medically tailored meals program
Introduction: Medically tailored meals (MTMs) are home-delivered, nutritionally tailored meals designed for patients with complex or advanced diet-sensitive medical conditions and social stressors. Although MTM use can improve food security, diet quality, and health outcomes, and reduce overall healthcare use and cost, little is known about why patients enroll in, stay in, or withdraw from such programs. Methods: Between June 2023 and May 2024, w…
Global, regional and national intake of plant-based foods among youth in 185 countries (1990–2018)
INTRODUCTION: Healthful plant-based foods can improve youth nutrition and contribute to global targets such as Sustainable Development Goal (SDG) 2 on ending malnutrition, SDG3 improving health and SDG12 promoting sustainable diets, yet global intakes remain unquantified. METHODS: We analysed the Global Dietary Database, aggregating 1248 dietary surveys from 185 countries in a Bayesian hierarchical model adjusted for survey heterogeneity, tempora…
Health Systems Approaches for Advancing Implementation and Policy for Food is Medicine
FIM policies and clinical integration potentially offer an opportunity to address the root causes of cardiometabolic disease, better manage health care costs, and promote health equity. Continued research, policy reform, and clinician engagement are needed to realize the full potential of FIM in 21st century medical practice
Facilitators and barriers to reach and enrollment into a medically tailored meals program within a section 1115 Medicaid pilot
Introduction: Medically tailored meals (MTMs) are home-delivered, nutritionally tailored meals for individuals living with complex or advanced diet-sensitive medical conditions. In 2020, Massachusetts Medicaid implemented the Flexible Services Program (FSP) through a Section 1115 Demonstration, which funded novel nutrition programs, including MTMs, for high-risk patients through Accountable Care Organizations (ACOs). Little is known from the prac…
Fiscal Impact of Expanded Medicare Coverage for GLP-1 Receptor Agonists to Treat Obesity
This economic evaluation estimates that expanded Medicare coverage for GLP-1RAs would increase access and reduce obesity-related comorbidities but impose substantial costs over 10 years. Even with a moderate scenario (5% uptake, 20% adherence, and 30% additional price discount), net spending was still projected to reach $8 billion over a decade, underscoring the need for further price reductions, lower-cost strategies to prevent weight regain, an…
Veterans Affairs FreshConnectProduceRx
This pragmatic quasi-experimental intervention study will provide important new evidence about the impact of a produce prescription program for U.S. Veterans on health outcomes, healthcare costs, and patient-reported outcomes. The assessment of effectiveness and implementation processes and outcomes will inform the design and scaling of impactful, pragmatic, cost-effective programs for food insecure Veterans with diet-sensitive cardiometabolic co…
Harmonising dietary datasets for global surveillance
Objective: The Global Dietary Database (GDD) expanded its previous methods to harmonise and publicly disseminate individual-level dietary data from nutrition surveys worldwide. Design: Analysis of cross-sectional data. Setting: Global. Participants: General population. Methods: Comprehensive methods to streamline the harmonisation of primary, individual-level 24-h recall and food record data worldwide were developed. To standardise the varying fo…
Disclosure of mandatory and voluntary nutrition labelling information across major online food retailers in the USA
Objective: Nutrition labelling is mandatory on food products in retail stores, but compliance in the rapidly expanding online setting remains unclear. We assessed mandatory and voluntary labelling information across major U.S. online retailers. Design: Between January and August 2022, we evaluated a representative basket of sixty food and beverage items across eight product categories of ten major retailers. We evaluated online presence, accessib…
Regulation of Added Substances in the Food Supply by the Food and Drug Administration Human Foods Program
The US food supply is increasingly associated with diet-related diseases, toxicity, cancer, and other health harms. These public health concerns are partly attributable to a loophole in federal law. The Food and Drug Administration (FDA) evaluates the premarket safety of ingredients regulated as food additives but allows the food industry to self-regulate and determine which substances to classify as generally recognized as safe (GRAS) based on u…
Oral iron supplementation and anaemia in children according to schedule, duration, dose and cosupplementation
Opportunities to address the failure of online food retailers to ensure access to required food labelling information in the USA
Objective: The rapid growth in web-based grocery food purchasing has outpaced federal regulatory attention to the online provision of nutrition and allergen information historically required on food product labels. We sought to characterise the extent and variability that online retailers disclose required and regulated information and identify the legal authorities for the federal government to require online food retailers to disclose such info…
Global Dietary Database 2017
BACKGROUND: We aimed to systematically identify, standardise and disseminate individual-level dietary intake surveys from up to 207 countries for 54 foods, beverages and nutrients, including subnational intakes by age, sex, education and urban/rural residence, from 1980 to 2015. METHODS: Between 2008-2011 and 2014-2020, the Global Dietary Database (GDD) project systematically searched for surveys assessing individual-level intake worldwide. We pr…
Impact of diet on CVD and diabetes mortality in Latin America and the Caribbean
Objective: To quantify diet-related burdens of cardiometabolic diseases (CMD) by country, age and sex in Latin America and the Caribbean (LAC). Design: Intakes of eleven key dietary factors were obtained from the Global Dietary Database Consortium. Aetiologic effects of dietary factors on CMD outcomes were obtained from meta-analyses. We combined these inputs with cause-specific mortality data to compute country-, age- and sex-specific absolute a…
Disparities in Health and Economic Burdens of Cancer Attributable to Suboptimal Diet in the United States, 2015‒2018
Objectives. To quantify disparities in health and economic burdens of cancer attributable to suboptimal diet among US adults. Methods. Using a probabilistic cohort state-transition model, we estimated the number of new cancer cases and cancer deaths, and economic costs of 15 diet-related cancers attributable to suboptimal intake of 7 dietary factors (a low intake of fruits, vegetables, dairy, and whole grains and a high intake of red and processe…
The International Diet-Health Index
Introduction Diet is a major modifiable risk factor for cardiometabolic disease; however, interpretable measures capturing impacts of overall diet on health that can be easily used by policymakers at the global/national levels are not readily available. Methods We developed the International Diet-Health Index (IDHI) to measure health impacts of dietary intake across 186 countries in 2010, using age-specific and sex-specific data on country-level …
Federal, State, and Local Nutrition Policies for Cancer Prevention
Objectives. To assess stakeholder perceptions of the impact and feasibility of 21 national, state, and local nutrition policies for cancer prevention across 5 domains in the United States. Methods. We conducted an online survey from October through December 2018. Participants were invited to take the survey via direct e-mail contact or an organizational e-newsletter. Results. Federal or state Medicare/Medicaid coverage of nutrition counseling and…
The obesity transition
Health effects of dietary risks in 195 countries, 1990–2017
BACKGROUND: Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the consumption of major foods and nutrients across 195 countries and to quantify the impact of their suboptimal intake on NCD mortality and morbidity. METHODS: By use of a comparative risk assessment approach, we estimated the propor…
Effects of animal protein supplementation of mothers, preterm infants, and term infants on growth outcomes in childhood
Mandating front-of-package food labels in the U.S. – What are the First Amendment obstacles
Cost-Effectiveness of a US National Sugar-Sweetened Beverage Tax With a Multistakeholder Approach
Objectives. To estimate the health impact and cost-effectiveness of a national penny-per-ounce sugar-sweetened beverage (SSB) tax, overall and with stratified costs and benefits for 9 distinct stakeholder groups. Methods. We used a validated microsimulation model (CVD PREDICT) to estimate cardiovascular disease reductions, quality-adjusted life years gained, and cost-effectiveness for US adults aged 35 to 85 years, evaluating full and partial con…
Dairy foods, dairy fat, diabetes, and death
Reply to H Kahleova and ND Barnard
The State of US Health, 1990-2016
Introduction: Several studies have measured health outcomes in the United States, but none have provided a comprehensive assessment of patterns of health by state. Objective: To use the results of the Global Burden of Disease Study (GBD) to report trends in the burden of diseases, injuries, and risk factors at the state level from 1990 to 2016. Design and Setting: A systematic analysis of published studies and available data sources estimates the…
Role of government policy in nutrition—barriers to and opportunities for healthier eating
Dariush Mozaffarian and colleagues review strategies governments can use to improve nutrition and health
Viewpoint
Cost-Effectiveness of a US National Sugar-Sweetened Beverage Tax With a Multistakeholder Approach
Objectives. To estimate the health impact and cost-effectiveness of a national penny-per-ounce sugar-sweetened beverage (SSB) tax, overall and with stratified costs and benefits for 9 distinct stakeholder groups. Methods. We used a validated microsimulation model (CVD PREDICT) to estimate cardiovascular disease reductions, quality-adjusted life years gained, and cost-effectiveness for US adults aged 35 to 85 years, evaluating full and partial con…
Legal and Administrative Feasibility of a Federal Junk Food and Sugar-Sweetened Beverage Tax to Improve Diet
Objectives. To evaluate legal and administrative feasibility of a federal “junk” food (including sugar-sweetened beverages [SSBs]) tax to improve diet. Methods. To assess food definitions and administration models, we systematically searched (1) PubMed (through May 15, 2017) for articles defining foods subject to taxes, and legal and legislative databases as well as online for (2) US federal, state, and tribal junk food tax bills and laws (Januar…
Cardiometabolic Mortality by Supplemental Nutrition Assistance Program Participation and Eligibility in the United States
Objectives. To investigate total and cause-specific cardiometabolic mortality among Supplemental Nutrition Assistance Program (SNAP) participants, SNAP-eligible nonparticipants, and SNAP-ineligible individuals overall and by age, gender, race/ethnicity, and other characteristics. Methods. We performed a prospective study with nationally representative survey data from the National Health Interview Survey (2000–2009), merged with subsequent Public…
Regulation of Added Substances in the Food Supply by the Food and Drug Administration Human Foods Program
The US food supply is increasingly associated with diet-related diseases, toxicity, cancer, and other health harms. These public health concerns are partly attributable to a loophole in federal law. The Food and Drug Administration (FDA) evaluates the premarket safety of ingredients regulated as food additives but allows the food industry to self-regulate and determine which substances to classify as generally recognized as safe (GRAS) based on u…
Disparities in Health and Economic Burdens of Cancer Attributable to Suboptimal Diet in the United States, 2015‒2018
Objectives. To quantify disparities in health and economic burdens of cancer attributable to suboptimal diet among US adults. Methods. Using a probabilistic cohort state-transition model, we estimated the number of new cancer cases and cancer deaths, and economic costs of 15 diet-related cancers attributable to suboptimal intake of 7 dietary factors (a low intake of fruits, vegetables, dairy, and whole grains and a high intake of red and processe…
Designing programs to improve diets for maternal and child health
Improving maternal and child nutrition in resource-poor settings requires effective use of limited resources, but priority-setting is constrained by limited information about program costs and impacts, especially for interventions designed to improve diet quality. This study utilized a mixed methods approach to identify, describe and estimate the potential costs and impacts on child dietary intake of 12 nutrition-sensitive programs in Ethiopia, N…
Keeping Soda in Snap
Fish Intake, Contaminants, and Human Health
CONTEXT: Fish (finfish or shellfish) may have health benefits and also contain contaminants, resulting in confusion over the role of fish consumption in a healthy diet. EVIDENCE ACQUISITION: We searched MEDLINE, governmental reports, and meta-analyses, supplemented by hand reviews of references and direct investigator contacts, to identify reports published through April 2006 evaluating (1) intake of fish or fish oil and cardiovascular risk, (2) …
The Preventable Causes of Death in the United States
BACKGROUND: Knowledge of the number of deaths caused by risk factors is needed for health policy and priority setting. Our aim was to estimate the mortality effects of the following 12 modifiable dietary, lifestyle, and metabolic risk factors in the United States (US) using consistent and comparable methods: high blood glucose, low-density lipoprotein (LDL) cholesterol, and blood pressure; overweight-obesity; high dietary trans fatty acids and sa…
Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction
This document details the procedures and recommendations of the Goals and Metrics Committee of the Strategic Planning Task Force of the American Heart Association, which developed the 2020 Impact Goals for the organization. The committee was charged with defining a new concept, cardiovascular health , and determining the metrics needed to monitor it over time. Ideal cardiovascular health, a concept well supported in the literature, is defined by …
Interventions to Promote Physical Activity and Dietary Lifestyle Changes for Cardiovascular Risk Factor Reduction in Adults
A pproximately 79 400 000 American adults, or 1 in 3, have cardiovascular disease (CVD). 1 CVD accounts for 36.3% or 1 of every 2.8 deaths in the United States and is the leading cause of death among both men and women in the United States, killing an average of 1 American every 37 seconds. 1 Older adults, some ethnic minority populations, and socioeconomically disadvantaged individuals have an increased prevalence of CVD and vascular/metabolic r…
Red and Processed Meat Consumption and Risk of Incident Coronary Heart Disease, Stroke, and Diabetes Mellitus
Background— Meat consumption is inconsistently associated with development of coronary heart disease (CHD), stroke, and diabetes mellitus, limiting quantitative recommendations for consumption levels. Effects of meat intake on these different outcomes, as well as of red versus processed meat, may also vary. Methods and Results— We performed a systematic review and meta-analysis of evidence for relationships of red (unprocessed), processed, and to…
Heart Disease and Stroke Statistics—2011 Update
Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a valuable resource for researchers, clinicians, h…
Non-communicable diseases in sub-Saharan Africa
BACKGROUND: Sub-Saharan Africa (SSA) has a disproportionate burden of both infectious and chronic diseases compared with other world regions. Current disease estimates for SSA are based on sparse data, but projections indicate increases in non-communicable diseases (NCDs) caused by demographic and epidemiologic transitions. We review the literature on NCDs in SSA and summarize data from the World Health Organization and International Agency for R…
Changes in Diet and Lifestyle and Long-Term Weight Gain in Women and Men
BACKGROUND: Specific dietary and other lifestyle behaviors may affect the success of the straightforward-sounding strategy "eat less and exercise more" for preventing long-term weight gain. METHODS: We performed prospective investigations involving three separate cohorts that included 120,877 U.S. women and men who were free of chronic diseases and not obese at baseline, with follow-up periods from 1986 to 2006, 1991 to 2003, and 1986 to 2006. Th…
Voluntary reduction of trans-fatty acids in Latin America and the Caribbean
As part of the Pan American Health Organization/World Health Organization Trans-Fat-Free Americas initiative, 12 representatives from food industries in Latin America and the Caribbean signed a declaration stating their intention to voluntarily eliminate industrially produced trans-fatty acids (TFA) from the Americas. A year later, in order to document the extent of the voluntary reduction, each declarant was asked to describe all reformulations …
O5-3.3 Global burdens of chronic disease attributable to suboptimal dietary habits
Introduction Little quantitative data are available on the global impact of diet on chronic diseases, including cardiovascular diseases, type 2 diabetes and cancer. Methods We used a comparative risk assessment framework to develop systematic and comparable methods to establish for selected dietary risk factors the effect sizes of probable or convincing causal diet-disease relationships; the alternative minimum risk exposure distribution; and the…
O5-3.2 Characterising global dietary habits related to chronic disease in the 21st century
Introduction Understanding the impact of diet on chronic diseases globally has been limited by lack of systematically collected and comparable data on dietary habits on a global scale. Methods We developed methods to collect nationally representative data on exposure distributions of 20 major dietary risk factors globally and in 21 world regions (196 countries), including total energy, fruits, fruit juices, vegetables, beans / legumes, nuts / see…
Population Approaches to Improve Diet, Physical Activity, and Smoking Habits
BACKGROUND: Poor lifestyle behaviors, including suboptimal diet, physical inactivity, and tobacco use, are leading causes of preventable diseases globally. Although even modest population shifts in risk substantially alter health outcomes, the optimal population-level approaches to improve lifestyle are not well established. METHODS AND RESULTS: For this American Heart Association scientific statement, the writing group systematically reviewed an…
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010
Do healthier foods and diet patterns cost more than less healthy options? A systematic review and meta-analysis
Heart Disease and Stroke Statistics—2013 Update
Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update*The Statistical Update is a valuable resource for researchers, clinicians, he…
Identifying whole grain foods
Objective Eating whole grains (WG) is recommended for health, but multiple conflicting definitions exist for identifying whole grain (WG) products, limiting the ability of consumers and organizations to select such products. We investigated how five recommended WG criteria relate to healthfulness and price of grain products. Design We categorized grain products by different WG criteria including: the industry-sponsored Whole Grain stamp (WG-Stamp…
Global Sodium Consumption and Death from Cardiovascular Causes
BACKGROUND: High sodium intake increases blood pressure, a risk factor for cardiovascular disease, but the effects of sodium intake on global cardiovascular mortality are uncertain. METHODS: We collected data from surveys on sodium intake as determined by urinary excretion and diet in persons from 66 countries (accounting for 74.1% of adults throughout the world), and we used these data to quantify the global consumption of sodium according to ag…
Heart Disease and Stroke Statistics—2014 Update
Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a critical resource for researchers, clinicians, h…
Global, Regional, and National Consumption of Sugar-Sweetened Beverages, Fruit Juices, and Milk
BACKGROUND: Sugar-sweetened beverages (SSBs), fruit juice, and milk are components of diet of major public health interest. To-date, assessment of their global distributions and health impacts has been limited by insufficient comparable and reliable data by country, age, and sex. OBJECTIVE: To quantify global, regional, and national levels of SSB, fruit juice, and milk intake by age and sex in adults over age 20 in 2010. METHODS: We identified, o…
Estimated Global, Regional, and National Disease Burdens Related to Sugar-Sweetened Beverage Consumption in 2010
BACKGROUND: Sugar-sweetened beverages (SSBs) are consumed globally and contribute to adiposity. However, the worldwide impact of SSBs on burdens of adiposity-related cardiovascular diseases (CVDs), cancers, and diabetes mellitus has not been assessed by nation, age, and sex. METHODS AND RESULTS: We modeled global, regional, and national burdens of disease associated with SSB consumption by age/sex in 2010. Data on SSB consumption levels were pool…
Consumption of ultra-processed foods and obesity in Brazilian adolescents and adults
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013
Dietary quality among men and women in 187 countries in 1990 and 2010
BACKGROUND: Healthy dietary patterns are a global priority to reduce non-communicable diseases. Yet neither worldwide patterns of diets nor their trends with time are well established. We aimed to characterise global changes (or trends) in dietary patterns nationally and regionally and to assess heterogeneity by age, sex, national income, and type of dietary pattern. METHODS: In this systematic assessment, we evaluated global consumption of key d…
Global, regional, and national disability-adjusted life years (Dalys) for 306 diseases and injuries and healthy life expectancy (Hale) for 188 countries, 1990–2013
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013
Medicine (53 obras) · Environmental health (42 obras) · Nutritional Studies and Diet (29 obras) · Population (21 obras) · Obesity, Physical Activity, Diet (19 obras) · Consumer Attitudes and Food Labeling (17 obras) · Demography (17 obras) · Disease (16 obras) · Gerontology (16 obras) · Internal Medicine (16 obras)