Hiroshi Odaguchi
Dados Biográficos
| ID | 7284151 |
|---|---|
| NOME | Hiroshi Odaguchi |
| PRENOMES | Hiroshi |
| SOBRENOME | Odaguchi |
| ASSINATURA | ODAGUCHI H |
| AFILIAÇÕES | Kitasato Institute Hospital |
| ORCID | 0000-0002-8863-1557 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 2 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 2 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2023 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2024 |
| ÍNDICE H | 0 |
Intron retention as an excellent marker for diagnosing depression and for discovering new potential pathways for drug intervention
Depression was found to be associated with activation of the innate immune response and relative inactivation of T-cell signaling. The DEGs we identified reflect physiological demands that are controlled at the transcriptional level, whereas the IR results reflect a more direct mechanism for monitoring protein homeostasis. Accordingly, an alteration in IR, namely IncIR or DecIR, is a stress response, and intron-retained transcripts are sensors of…
Overlooked switch from transient sedation to sustained excitement in the Biphasic effects of Ephedra Herb extract administered orally to mice
We discovered for the first time that EHE evokes diphasic action by switching from transient sedation to sustained excitement. The transient sedation was evoked by the Eph and Pse in the herbal extract via activation of the α2a adrenoceptor and the sustained excitement was caused by the Eph in the herbal extract
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Overlooked switch from transient sedation to sustained excitement in the Biphasic effects of Ephedra Herb extract administered orally to mice
We discovered for the first time that EHE evokes diphasic action by switching from transient sedation to sustained excitement. The transient sedation was evoked by the Eph and Pse in the herbal extract via activation of the α2a adrenoceptor and the sustained excitement was caused by the Eph in the herbal extract
Intron retention as an excellent marker for diagnosing depression and for discovering new potential pathways for drug intervention
Depression was found to be associated with activation of the innate immune response and relative inactivation of T-cell signaling. The DEGs we identified reflect physiological demands that are controlled at the transcriptional level, whereas the IR results reflect a more direct mechanism for monitoring protein homeostasis. Accordingly, an alteration in IR, namely IncIR or DecIR, is a stress response, and intron-retained transcripts are sensors of…
Anesthesia (1 obras) · Antidepressant (1 obras) · Behavioural despair test (1 obras) · Biology (1 obras) · Chemical synthesis and alkaloids (1 obras) · Depression (economics (1 obras) · Ephedrine (1 obras) · Gene (1 obras) · Genetics (1 obras) · Herb (1 obras)