Kristin N Harper
Dados Biográficos
| ID | 74880 |
|---|---|
| NOME | Kristin N Harper |
| PRENOMES | Kristin N |
| SOBRENOME | Harper |
| ASSINATURA | HARPER K N |
| AFILIAÇÕES | Emory University |
| ORCID | 0000-0002-5181-1263 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 12 |
| TOTAL DE CITAÇÕES | 59 |
| TOTAL COMO AUTOR | 12 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2005 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2023 |
| ÍNDICE H | 3 |
Best practices in the African Medicines Regulatory Harmonization initiative
In the African Medicines Regulatory Harmonization initiative, national regulatory authorities (NRAs) within each of Africa’s regional economic communities coordinate their activities, rely on the work of one another and other trusted regulatory authorities, and apply other principles of smart regulation. The first regional medicines regulatory harmonization (MRH) initiative in Africa was launched in 2012, with the goal of accelerating access to q…
Adapt or Die
Over the past several decades, the field of paleopathology has rapidly advanced, but a continuing delay in incorporating scientific advances and a lack of methodological rigor hinder its progress. Inconsistencies in the presentation of data, the persistent use of non-standardized criteria and non-specific skeletal lesions to diagnose diseases, and the misuse of or delay in adopting critical, relevant concepts and methods from other disciplines ob…
George J. Armelagos (1936–2014)
The evolution of disease
BACKGROUND: The model of epidemiologic transitions has served as a guiding framework for understanding relationships between patterns of human health and disease and economic development for the past several decades. However, epidemiologic transition theory is infrequently employed in epidemiology. OBJECTIVE: Moving beyond Omran's original formulation, we discuss critiques and modifications of the theory of epidemiologic transitions and highlight…
Genomics, the origins of agriculture, and our changing microbe‐scape
Though agriculture is often viewed as one of humanity's crowning achievements, skeletal evidence indicates that dependence on domesticated plants and animals was accompanied by an increase in infectious disease. Scientists have proposed that many important infections emerged in the period following the advent of agriculture, as a result of newly dense populations and novel proximity to domestic animals that served as reservoirs for novel pathogen…
Response to Cole and Waldron's “letter to the editor
The Science Behind Pre‐Columbian Evidence of Syphilis in Europe
This article discusses the presentation of scientific findings by documentary, without the process of peer review. We use, as an example, PBS's “The Syphilis Enigma,” in which researchers presented novel evidence concerning the origin of syphilis that had never been reviewed by other scientists. These “findings” then entered the world of peer‐reviewed literature through citations of the documentary itself or material associated with it. Here, we …
The origin and antiquity of syphilis revisited
For nearly 500 years, scholars have argued about the origin and antiquity of syphilis. Did Columbus bring the disease from the New World to the Old World? Or did syphilis exist in the Old World before 1493? Here, we evaluate all 54 published reports of pre-Columbian, Old World treponemal disease using a standardized, systematic approach. The certainty of diagnosis and dating of each case is considered, and novel information pertinent to the datin…
Enamel hypoplasia and early mortality
The Barker hypothesis asserts that stressful events early in the life history of an individual have negative health consequences later in adulthood. The hypothesis initially focused on prenatal stressors as indicated by birth weight and related outcomes. This initial concern with the fetal phase of development led to its description as the “fetal programming” or “fetal origins” hypothesis. The realization that stressors in the postnatal phase had…
Genomics at the origins of agriculture, part two
Agricultural expansion was such a momentous event that cultural or genetic evidence of its impact should be apparent. Abundant evidence indicates that agriculture was introduced into Europe at least 9,000 years ago. The primary issue remains whether agriculture spread by contact or by farmers moving into Europe. If agriculture was brought by farmers moving into foragers' territory, then genetic evidence should be apparent in the genes of modern E…
Genomics at the origins of agriculture, part one
The causes and consequences of the Neolithic revolution represent a fundamental problem for anthropological inquiry. Traditional archeological evidence, ethnobotanical remains, artifacts, and settlement patterns have been used to infer the transition from foraging to primary food production. Recent advances in genomics (the study of the sequence, structure, and function of the genome) has enhanced our understanding of the process of plant and ani…
On the Trail of the Twisted Treponeme
The origin and antiquity of syphilis revisited
For nearly 500 years, scholars have argued about the origin and antiquity of syphilis. Did Columbus bring the disease from the New World to the Old World? Or did syphilis exist in the Old World before 1493? Here, we evaluate all 54 published reports of pre-Columbian, Old World treponemal disease using a standardized, systematic approach. The certainty of diagnosis and dating of each case is considered, and novel information pertinent to the datin…
Genomics, the origins of agriculture, and our changing microbe‐scape
Though agriculture is often viewed as one of humanity's crowning achievements, skeletal evidence indicates that dependence on domesticated plants and animals was accompanied by an increase in infectious disease. Scientists have proposed that many important infections emerged in the period following the advent of agriculture, as a result of newly dense populations and novel proximity to domestic animals that served as reservoirs for novel pathogen…
On the Trail of the Twisted Treponeme
Adapt or Die
Over the past several decades, the field of paleopathology has rapidly advanced, but a continuing delay in incorporating scientific advances and a lack of methodological rigor hinder its progress. Inconsistencies in the presentation of data, the persistent use of non-standardized criteria and non-specific skeletal lesions to diagnose diseases, and the misuse of or delay in adopting critical, relevant concepts and methods from other disciplines ob…
The Science Behind Pre‐Columbian Evidence of Syphilis in Europe
This article discusses the presentation of scientific findings by documentary, without the process of peer review. We use, as an example, PBS's “The Syphilis Enigma,” in which researchers presented novel evidence concerning the origin of syphilis that had never been reviewed by other scientists. These “findings” then entered the world of peer‐reviewed literature through citations of the documentary itself or material associated with it. Here, we …
Genomics at the origins of agriculture, part two
Agricultural expansion was such a momentous event that cultural or genetic evidence of its impact should be apparent. Abundant evidence indicates that agriculture was introduced into Europe at least 9,000 years ago. The primary issue remains whether agriculture spread by contact or by farmers moving into Europe. If agriculture was brought by farmers moving into foragers' territory, then genetic evidence should be apparent in the genes of modern E…
Genomics at the origins of agriculture, part one
The causes and consequences of the Neolithic revolution represent a fundamental problem for anthropological inquiry. Traditional archeological evidence, ethnobotanical remains, artifacts, and settlement patterns have been used to infer the transition from foraging to primary food production. Recent advances in genomics (the study of the sequence, structure, and function of the genome) has enhanced our understanding of the process of plant and ani…
On the Trail of the Twisted Treponeme
Enamel hypoplasia and early mortality
The Barker hypothesis asserts that stressful events early in the life history of an individual have negative health consequences later in adulthood. The hypothesis initially focused on prenatal stressors as indicated by birth weight and related outcomes. This initial concern with the fetal phase of development led to its description as the “fetal programming” or “fetal origins” hypothesis. The realization that stressors in the postnatal phase had…
The origin and antiquity of syphilis revisited
For nearly 500 years, scholars have argued about the origin and antiquity of syphilis. Did Columbus bring the disease from the New World to the Old World? Or did syphilis exist in the Old World before 1493? Here, we evaluate all 54 published reports of pre-Columbian, Old World treponemal disease using a standardized, systematic approach. The certainty of diagnosis and dating of each case is considered, and novel information pertinent to the datin…
Response to Cole and Waldron's “letter to the editor
The Science Behind Pre‐Columbian Evidence of Syphilis in Europe
This article discusses the presentation of scientific findings by documentary, without the process of peer review. We use, as an example, PBS's “The Syphilis Enigma,” in which researchers presented novel evidence concerning the origin of syphilis that had never been reviewed by other scientists. These “findings” then entered the world of peer‐reviewed literature through citations of the documentary itself or material associated with it. Here, we …
Genomics, the origins of agriculture, and our changing microbe‐scape
Though agriculture is often viewed as one of humanity's crowning achievements, skeletal evidence indicates that dependence on domesticated plants and animals was accompanied by an increase in infectious disease. Scientists have proposed that many important infections emerged in the period following the advent of agriculture, as a result of newly dense populations and novel proximity to domestic animals that served as reservoirs for novel pathogen…
George J. Armelagos (1936–2014)
The evolution of disease
BACKGROUND: The model of epidemiologic transitions has served as a guiding framework for understanding relationships between patterns of human health and disease and economic development for the past several decades. However, epidemiologic transition theory is infrequently employed in epidemiology. OBJECTIVE: Moving beyond Omran's original formulation, we discuss critiques and modifications of the theory of epidemiologic transitions and highlight…
Adapt or Die
Over the past several decades, the field of paleopathology has rapidly advanced, but a continuing delay in incorporating scientific advances and a lack of methodological rigor hinder its progress. Inconsistencies in the presentation of data, the persistent use of non-standardized criteria and non-specific skeletal lesions to diagnose diseases, and the misuse of or delay in adopting critical, relevant concepts and methods from other disciplines ob…
Best practices in the African Medicines Regulatory Harmonization initiative
In the African Medicines Regulatory Harmonization initiative, national regulatory authorities (NRAs) within each of Africa’s regional economic communities coordinate their activities, rely on the work of one another and other trusted regulatory authorities, and apply other principles of smart regulation. The first regional medicines regulatory harmonization (MRH) initiative in Africa was launched in 2012, with the goal of accelerating access to q…
Biology (6 obras) · Yersinia bacterium, plague, ectoparasites research (5 obras) · Evolutionary biology (4 obras) · Genetics (4 obras) · Geography (4 obras) · Medicine (4 obras) · Agriculture (3 obras) · Archaeology (3 obras) · Computer Science (3 obras) · Ecology (3 obras)