YanYan Wei
Dados Biográficos
| ID | 7683705 |
|---|---|
| NOME | YanYan Wei |
| PRENOMES | YanYan |
| SOBRENOME | Wei |
| ASSINATURA | WEI Y |
| AFILIAÇÕES | Shanghai Mental Health Center |
| ORCID | 0000-0002-8218-1954 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 17 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 17 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2017 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 0 |
Modeling Long-Term Emotional Support Through Causal World Modeling With Imitation Learning
Emotional support conversation systems have emerged as a promising complement to traditional mental health consultations, offering context-aware dialogue to support seekers’ emotional well-being. Despite their potential, two fundamental challenges remain unresolved: 1) modeling long-term emotional trajectory beyond short-term relief; and 2) adapting support strategies to context in a psychologically coherent manner. To address these challenges, w…
Proteome-wide Mendelian randomization and colocalization analyses identify potential biomarkers for schizophrenia
This large-scale MR study provides robust evidence supporting causal roles for specific plasma proteins in SCZ pathogenesis, highlighting promising candidates for mechanistic studies and therapeutic development
Investigation of serum cystatin C levels and their diagnostic value in combination with inflammatory ratios in patients with bipolar disorder
The cross-sectional study is limited to demonstrating associations rather than establishing causality. A thorough examination of sociodemographic factors and the severity of the disease could not be conducted
Gender differences in neurocognitive impairment among first-episode, drug-naïve schizophrenia patients
FES manifests as sex-divergent cognitive profiles, with males showing executive/processing speed deficits tied to negative symptoms and females exhibiting memory impairments with broader symptom associations. These findings underscore the need for sex-sensitive approaches in characterizing cognitive dysfunction in early psychosis
Effectiveness of magnetic seizure therapy versus electroconvulsive therapy for major depressive episode in China
ClinicalTrials.gov, identifier NCT06409325
Age-related differences in borderline personality disorder traits and childhood maltreatment
The findings underscore the importance of age-specific interventions in treating BPD and addressing childhood maltreatment. Adolescents exhibit distinct patterns of BPD traits and CM experiences, necessitating tailored therapeutic approaches
Distribution of self-reported borderline personality disorder traits symptoms in a large-scale clinical population
Our study revealed the pervasive presence of BPD traits and symptoms among psychiatric outpatients, exhibiting distinctive distributions across gender, age, and diagnostic categories. These findings emphasize the significance of identifying and addressing BPD pathology in the clinical care of psychiatric outpatients
Childhood maltreatment and personality disorders in adolescents and adults with psychotic or non-psychotic disorders
The findings emphasize distinct differences in PDs and CMs between adolescent and adult groups, shedding light on their potential roles in psychotic and non-psychotic disorders
Increased anxiety and stress-related visits to the Shanghai psychiatric emergency department during the Covid-19 pandemic in 2020 compared to 2018–2019
Despite the epidemic-policy barriers against PED visits, PED care seeking has increased, thereby underscoring the need for crisis prevention services for patients with stress and anxiety disorders
Psychiatric emergency department visits during the coronavirus disease-2019 pandemic
These findings suggest that PED care-seeking increases during the COVID-19 pandemic, highlighting the need to integrate mental health services for patients with stress, sleep, anxiety, and obsessive-compulsive disorders during public health crises
Relation Between Unconjugated Bilirubin and Peripheral Biomarkers of Inflammation Derived From Complete Blood Counts in Patients With Acute Stage of Schizophrenia
UCB has a protective effect on acute stage of schizophrenia, which is weak and indirect by affecting the proinflammatory processes. Our findings suggest that a combination of MLR, MPV, PLR, and UBC could be used to predict acute stage of schizophrenia
Investigation of systemic immune-inflammation index, neutrophil/high-density lipoprotein ratio, lymphocyte/high-density lipoprotein ratio, and monocyte/high-density lipoprotein ratio as indicators of …
Our study highlights the role of systemic inflammation in the pathophysiology of SCZ, BD-M, and BD-D, the association between inflammation and lipid metabolism, and these inflammation and lipid metabolism indicators showed different variation patterns in SCZ, BD-D, and BD-M
Relationship Between Cognitive and Clinical Insight at Different Durations of Untreated Attenuated Psychotic Symptoms in High-Risk Individuals
Background: This study examines whether cognitive insight is impaired in high-risk individuals with attenuated psychotic symptoms (APS) and explores the relationship between cognitive and clinical insight at different durations of untreated attenuated psychotic symptoms (DUAPS). Methods: The Structured Interview for Psychosis high-risk Syndrome (SIPS) was used to identify APS individuals. APS ( n = 121) and healthy control (HC, n = 87) subjects w…
Inadequate Mental Health Literacy and Insufficient Physical Activity Potentially Increase the Risks of Anxiety and Depressive Symptoms in Chinese College Students
Objective: The present study aimed to examine the interactive associations between physical activity and mental health literacy with anxiety and depressive symptoms in Chinese college students. Methods: A cross-sectional study was conducted from May to July 2020. A total of 7,512 students were recruited from two medical colleges in Hefei and Anqing city in Anhui Province, China. Physical activity, mental health literacy, anxiety and depressive sy…
Tumor Necrosis Factor-α Variations in Patients With Major Depressive Disorder Before and After Antidepressant Treatment
Tumor necrosis factor-α (TNF-α) had been identified as a key pro-inflammatory cytokine in the pathophysiology of major depressive disorder (MDD) and the mechanism of antidepressant treatment. The primary aim of the present study was to examine the serum TNF-α levels in Chinese inpatients with MDD during the acute phase and to explore the changes in TNF-α levels after effective clinical treatment. Fifty-seven consecutive inpatients with MDD and 30…
Effect of Different Forms of Selenium on the Physiological Response and the Cadmium Uptake by Rice under Cadmium Stress
Cadmium (Cd) is a pollutant toxic to plants and a potential threat to human health. Selenium (Se), though not essential for plants, has beneficial effects on plants under abiotic stress. A hydroponic experiment was conducted to investigate the impact of different forms of Se (Nano-Se, selenite, selenate, and SeMet) on accumulation, subcellular distribution, and chemical forms of Cd, as well as oxidative stress in rice seedlings. Cd (20 μmol·L -1 …
Bioaccessibility and Human Exposure Assessment of Cadmium and Arsenic in Pakchoi Genotypes Grown in Co-Contaminated Soils
In many countries cadmium (Cd) and arsenic (As) commonly coexist in soils contaminated by mining activities, and can easily enter the human body via consumption of leafy vegetables, like the popularly consumed pakchoi ( Brassica chinensis L.), causing major health concerns. In the present study, bioaccessibility and human exposure of Cd and As were assessed in twenty genotypes of pakchoi cultured at two different levels of co-contamination to ide…
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Bioaccessibility and Human Exposure Assessment of Cadmium and Arsenic in Pakchoi Genotypes Grown in Co-Contaminated Soils
In many countries cadmium (Cd) and arsenic (As) commonly coexist in soils contaminated by mining activities, and can easily enter the human body via consumption of leafy vegetables, like the popularly consumed pakchoi ( Brassica chinensis L.), causing major health concerns. In the present study, bioaccessibility and human exposure of Cd and As were assessed in twenty genotypes of pakchoi cultured at two different levels of co-contamination to ide…
Tumor Necrosis Factor-α Variations in Patients With Major Depressive Disorder Before and After Antidepressant Treatment
Tumor necrosis factor-α (TNF-α) had been identified as a key pro-inflammatory cytokine in the pathophysiology of major depressive disorder (MDD) and the mechanism of antidepressant treatment. The primary aim of the present study was to examine the serum TNF-α levels in Chinese inpatients with MDD during the acute phase and to explore the changes in TNF-α levels after effective clinical treatment. Fifty-seven consecutive inpatients with MDD and 30…
Effect of Different Forms of Selenium on the Physiological Response and the Cadmium Uptake by Rice under Cadmium Stress
Cadmium (Cd) is a pollutant toxic to plants and a potential threat to human health. Selenium (Se), though not essential for plants, has beneficial effects on plants under abiotic stress. A hydroponic experiment was conducted to investigate the impact of different forms of Se (Nano-Se, selenite, selenate, and SeMet) on accumulation, subcellular distribution, and chemical forms of Cd, as well as oxidative stress in rice seedlings. Cd (20 μmol·L -1 …
Relationship Between Cognitive and Clinical Insight at Different Durations of Untreated Attenuated Psychotic Symptoms in High-Risk Individuals
Background: This study examines whether cognitive insight is impaired in high-risk individuals with attenuated psychotic symptoms (APS) and explores the relationship between cognitive and clinical insight at different durations of untreated attenuated psychotic symptoms (DUAPS). Methods: The Structured Interview for Psychosis high-risk Syndrome (SIPS) was used to identify APS individuals. APS ( n = 121) and healthy control (HC, n = 87) subjects w…
Inadequate Mental Health Literacy and Insufficient Physical Activity Potentially Increase the Risks of Anxiety and Depressive Symptoms in Chinese College Students
Objective: The present study aimed to examine the interactive associations between physical activity and mental health literacy with anxiety and depressive symptoms in Chinese college students. Methods: A cross-sectional study was conducted from May to July 2020. A total of 7,512 students were recruited from two medical colleges in Hefei and Anqing city in Anhui Province, China. Physical activity, mental health literacy, anxiety and depressive sy…
Relation Between Unconjugated Bilirubin and Peripheral Biomarkers of Inflammation Derived From Complete Blood Counts in Patients With Acute Stage of Schizophrenia
UCB has a protective effect on acute stage of schizophrenia, which is weak and indirect by affecting the proinflammatory processes. Our findings suggest that a combination of MLR, MPV, PLR, and UBC could be used to predict acute stage of schizophrenia
Investigation of systemic immune-inflammation index, neutrophil/high-density lipoprotein ratio, lymphocyte/high-density lipoprotein ratio, and monocyte/high-density lipoprotein ratio as indicators of …
Our study highlights the role of systemic inflammation in the pathophysiology of SCZ, BD-M, and BD-D, the association between inflammation and lipid metabolism, and these inflammation and lipid metabolism indicators showed different variation patterns in SCZ, BD-D, and BD-M
Increased anxiety and stress-related visits to the Shanghai psychiatric emergency department during the Covid-19 pandemic in 2020 compared to 2018–2019
Despite the epidemic-policy barriers against PED visits, PED care seeking has increased, thereby underscoring the need for crisis prevention services for patients with stress and anxiety disorders
Psychiatric emergency department visits during the coronavirus disease-2019 pandemic
These findings suggest that PED care-seeking increases during the COVID-19 pandemic, highlighting the need to integrate mental health services for patients with stress, sleep, anxiety, and obsessive-compulsive disorders during public health crises
Distribution of self-reported borderline personality disorder traits symptoms in a large-scale clinical population
Our study revealed the pervasive presence of BPD traits and symptoms among psychiatric outpatients, exhibiting distinctive distributions across gender, age, and diagnostic categories. These findings emphasize the significance of identifying and addressing BPD pathology in the clinical care of psychiatric outpatients
Childhood maltreatment and personality disorders in adolescents and adults with psychotic or non-psychotic disorders
The findings emphasize distinct differences in PDs and CMs between adolescent and adult groups, shedding light on their potential roles in psychotic and non-psychotic disorders
Investigation of serum cystatin C levels and their diagnostic value in combination with inflammatory ratios in patients with bipolar disorder
The cross-sectional study is limited to demonstrating associations rather than establishing causality. A thorough examination of sociodemographic factors and the severity of the disease could not be conducted
Gender differences in neurocognitive impairment among first-episode, drug-naïve schizophrenia patients
FES manifests as sex-divergent cognitive profiles, with males showing executive/processing speed deficits tied to negative symptoms and females exhibiting memory impairments with broader symptom associations. These findings underscore the need for sex-sensitive approaches in characterizing cognitive dysfunction in early psychosis
Effectiveness of magnetic seizure therapy versus electroconvulsive therapy for major depressive episode in China
ClinicalTrials.gov, identifier NCT06409325
Age-related differences in borderline personality disorder traits and childhood maltreatment
The findings underscore the importance of age-specific interventions in treating BPD and addressing childhood maltreatment. Adolescents exhibit distinct patterns of BPD traits and CM experiences, necessitating tailored therapeutic approaches
Modeling Long-Term Emotional Support Through Causal World Modeling With Imitation Learning
Emotional support conversation systems have emerged as a promising complement to traditional mental health consultations, offering context-aware dialogue to support seekers’ emotional well-being. Despite their potential, two fundamental challenges remain unresolved: 1) modeling long-term emotional trajectory beyond short-term relief; and 2) adapting support strategies to context in a psychologically coherent manner. To address these challenges, w…
Proteome-wide Mendelian randomization and colocalization analyses identify potential biomarkers for schizophrenia
This large-scale MR study provides robust evidence supporting causal roles for specific plasma proteins in SCZ pathogenesis, highlighting promising candidates for mechanistic studies and therapeutic development
Medicine (11 obras) · Psychiatry (11 obras) · Internal Medicine (8 obras) · Clinical Psychology (6 obras) · Clinical Psychology (6 obras) · Psychology (6 obras) · Tryptophan and brain disorders (5 obras) · Anxiety (4 obras) · Disease (4 obras) · Mental health (4 obras)