Andrea Spinazzè
Dados Biográficos
| ID | 7850442 |
|---|---|
| NOME | Andrea Spinazzè |
| PRENOMES | Andrea |
| SOBRENOME | Spinazzè |
| ASSINATURA | SPINAZZÈ A |
| AFILIAÇÕES | University of Insubria |
| ORCID | 0000-0003-0371-3164 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 10 |
| TOTAL DE CITAÇÕES | 0 |
| OBRAS COMO AUTOR | 10 |
| OBRAS COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2014 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 0 |
Occupational exposure to total and hexavalent chromium in welders
Introduction: Chromium (Cr), and particularly its hexavalent form is classified as a Group 1 human carcinogen and represents a major occupational hazard, particularly in stainless-steel welding. This exploratory study integrated environmental and biological monitoring to characterize welders' exposure and assessed how analytical methods influence exposure estimates. Methods: Twenty-two welders from two Northern Italian companies and 10 administra…
Theoretical Background of Occupational-Exposure Models—Report of an Expert Workshop of the Ises Europe Working Group “Exposure Models”
On 20 October 2020, the Working Group "Exposure Models" of the Europe Regional Chapter of the International Society of Exposure Science (ISES Europe) organised an online workshop to discuss the theoretical background of models for the assessment of occupational exposure to chemicals. In this report, participants of the workshop with an active role before and during the workshop summarise the most relevant discussion points and conclusions of this…
Asbestos Exposure in Patients with Malignant Pleural Mesothelioma included in the PRIMATE Study, Lombardy, Italy
The PRIMATE study is an Italian translational research project, which aims to identify personalized biomarkers associated with clinical characteristics of malignant pleural mesothelioma (MPM). For this purpose, characteristics of MPM patients with different degrees of asbestos exposure will be compared to identify somatic mutations, germline polymorphism, and blood inflammatory biomarkers. In this framework, we assessed exposure to asbestos for 5…
On the Determination of Cr(VI) in Cr(III)-Rich Particulates
The goals of this work are the evaluation of the performances of official methods in the challenging determination of Cr(VI) in Cr(III)-rich particulate matter, and the development of a novel and robust analytical protocol for this issue. A liquid chromatography inductively coupled plasma mass spectrometry apparatus (LC-ICP-MS), together with an isotope-enriched spike addition technique, was used to allow the study of Cr(III)/Cr(VI) interconversi…
Comparison between Communicated and Calculated Exposure Estimates Obtained through Three Modeling Tools
This study aims to evaluate the risk assessment approach of the REACH legislation in industrial chemical departments with a focus on the use of three models to calculate exposures, and discuss those factors that can determine a bias between the estimated exposure (and therefore the expected risk) in the extended safety data sheets (e-SDS) and the expected exposure for the actual scenario. To purse this goal, the exposure estimates and risk charac…
Commuters’ Personal Exposure Assessment and Evaluation of Inhaled Dose to Different Atmospheric Pollutants
Several studies evaluating exposure to pollutants in microenvironments (MEs) are available in the scientific literature, but studies that evaluate the inhaled doses of pollutants are few in number. Therefore, this study aimed to evaluate the exposure of commuters to different pollutants (i.e., nitrogen dioxide [NO 2 ] and fractionated particulate matter [PM], including ultrafine particles [UFPs]) using miniaturized and portable real-time monitori…
Inside Project
Hypertensive disorders are common complications during pregnancy (HDP) with substantial public health impact. Acute and chronic particulate matter (PM) exposure during pregnancy increases the risk of HDP, although the underlying molecular mechanisms remain unclear. Extracellular vesicles (EVs) may be the ideal candidates for mediating the effects of PM exposure in pregnancy as they are released in response to environmental stimuli. The INSIDE pro…
Estimation of the Inhaled Dose of Airborne Pollutants during Commuting
During rush hours, commuters are exposed to high concentrations and peaks of traffic-related air pollutants. The aims of this study were therefore to extend the inhaled dose estimation outcomes from a previous work investigating the inhaled dose of a typical commuter in the city of Milan, Italy, and to extend these results to a wider population. The estimation of the dose of pollutants inhaled by commuters and deposited within the respiratory tra…
Modeling Population Exposure to Ultrafine Particles in a Major Italian Urban Area
Average daily ultrafine particles (UFP) exposure of adult Milan subpopulations (defined on the basis of gender, and then for age, employment or educational status), in different exposure scenarios (typical working day in summer and winter) were simulated using a microenvironmental stochastic simulation model. The basic concept of this kind of model is that time-weighted average exposure is defined as the sum of partial microenvironmental exposure…
Airborne Particulate Matter in School Classrooms of Northern Italy
Indoor size-fractioned particulate matter (PM) was measured in seven schools in Milan, to characterize their concentration levels in classrooms, compare the measured concentrations with the recommended guideline values, and provide a preliminary assessment of the efficacy of the intervention measures, based on the guidelines developed by the Italian Ministry of Healthand applied to mitigate exposure to undesirable air pollutants. Indoor sampling …
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Modeling Population Exposure to Ultrafine Particles in a Major Italian Urban Area
Average daily ultrafine particles (UFP) exposure of adult Milan subpopulations (defined on the basis of gender, and then for age, employment or educational status), in different exposure scenarios (typical working day in summer and winter) were simulated using a microenvironmental stochastic simulation model. The basic concept of this kind of model is that time-weighted average exposure is defined as the sum of partial microenvironmental exposure…
Airborne Particulate Matter in School Classrooms of Northern Italy
Indoor size-fractioned particulate matter (PM) was measured in seven schools in Milan, to characterize their concentration levels in classrooms, compare the measured concentrations with the recommended guideline values, and provide a preliminary assessment of the efficacy of the intervention measures, based on the guidelines developed by the Italian Ministry of Healthand applied to mitigate exposure to undesirable air pollutants. Indoor sampling …
Comparison between Communicated and Calculated Exposure Estimates Obtained through Three Modeling Tools
This study aims to evaluate the risk assessment approach of the REACH legislation in industrial chemical departments with a focus on the use of three models to calculate exposures, and discuss those factors that can determine a bias between the estimated exposure (and therefore the expected risk) in the extended safety data sheets (e-SDS) and the expected exposure for the actual scenario. To purse this goal, the exposure estimates and risk charac…
Commuters’ Personal Exposure Assessment and Evaluation of Inhaled Dose to Different Atmospheric Pollutants
Several studies evaluating exposure to pollutants in microenvironments (MEs) are available in the scientific literature, but studies that evaluate the inhaled doses of pollutants are few in number. Therefore, this study aimed to evaluate the exposure of commuters to different pollutants (i.e., nitrogen dioxide [NO 2 ] and fractionated particulate matter [PM], including ultrafine particles [UFPs]) using miniaturized and portable real-time monitori…
Inside Project
Hypertensive disorders are common complications during pregnancy (HDP) with substantial public health impact. Acute and chronic particulate matter (PM) exposure during pregnancy increases the risk of HDP, although the underlying molecular mechanisms remain unclear. Extracellular vesicles (EVs) may be the ideal candidates for mediating the effects of PM exposure in pregnancy as they are released in response to environmental stimuli. The INSIDE pro…
Estimation of the Inhaled Dose of Airborne Pollutants during Commuting
During rush hours, commuters are exposed to high concentrations and peaks of traffic-related air pollutants. The aims of this study were therefore to extend the inhaled dose estimation outcomes from a previous work investigating the inhaled dose of a typical commuter in the city of Milan, Italy, and to extend these results to a wider population. The estimation of the dose of pollutants inhaled by commuters and deposited within the respiratory tra…
Theoretical Background of Occupational-Exposure Models—Report of an Expert Workshop of the Ises Europe Working Group “Exposure Models”
On 20 October 2020, the Working Group "Exposure Models" of the Europe Regional Chapter of the International Society of Exposure Science (ISES Europe) organised an online workshop to discuss the theoretical background of models for the assessment of occupational exposure to chemicals. In this report, participants of the workshop with an active role before and during the workshop summarise the most relevant discussion points and conclusions of this…
Asbestos Exposure in Patients with Malignant Pleural Mesothelioma included in the PRIMATE Study, Lombardy, Italy
The PRIMATE study is an Italian translational research project, which aims to identify personalized biomarkers associated with clinical characteristics of malignant pleural mesothelioma (MPM). For this purpose, characteristics of MPM patients with different degrees of asbestos exposure will be compared to identify somatic mutations, germline polymorphism, and blood inflammatory biomarkers. In this framework, we assessed exposure to asbestos for 5…
On the Determination of Cr(VI) in Cr(III)-Rich Particulates
The goals of this work are the evaluation of the performances of official methods in the challenging determination of Cr(VI) in Cr(III)-rich particulate matter, and the development of a novel and robust analytical protocol for this issue. A liquid chromatography inductively coupled plasma mass spectrometry apparatus (LC-ICP-MS), together with an isotope-enriched spike addition technique, was used to allow the study of Cr(III)/Cr(VI) interconversi…
Occupational exposure to total and hexavalent chromium in welders
Introduction: Chromium (Cr), and particularly its hexavalent form is classified as a Group 1 human carcinogen and represents a major occupational hazard, particularly in stainless-steel welding. This exploratory study integrated environmental and biological monitoring to characterize welders' exposure and assessed how analytical methods influence exposure estimates. Methods: Twenty-two welders from two Northern Italian companies and 10 administra…
Air Quality and Health Impacts (7 obras) · Medicine (7 obras) · Environmental health (6 obras) · Environmental Science (5 obras) · Chemistry (4 obras) · Geography (4 obras) · Biology (3 obras) · Environmental Chemistry (3 obras) · Mathematics (3 obras) · Meteorology (3 obras)