Guo‐Bo Chen
Dados Biográficos
| ID | 7977612 |
|---|---|
| NOME | Guo‐Bo Chen |
| PRENOMES | Guo‐Bo |
| SOBRENOME | Chen |
| ASSINATURA | CHEN G B |
| AFILIAÇÕES | The University of Queensland |
| ORCID | 0000-0001-5475-8237 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 3 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 3 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2016 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2022 |
| ÍNDICE H | 0 |
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder
Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…
Genome-wide association study identifies 74 loci associated with educational attainment
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Genome-wide association study identifies 74 loci associated with educational attainment
Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder
Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Biology (3 obras) · Birth, Development, and Health (2 obras) · Gene (2 obras) · Genetic association (2 obras) · Genetic Associations and Epidemiology (2 obras) · Genetics (2 obras) · Genetics and Neurodevelopmental Disorders (2 obras) · Genome (2 obras) · Genome-wide association study (2 obras) · Genotype (2 obras)