Kazutaka Kasai
Dados Biográficos
| ID | 95003 |
|---|---|
| NOME | Kazutaka Kasai |
| PRENOMES | Kazutaka |
| SOBRENOME | Kasai |
| ASSINATURA | KASAI K |
| AFILIAÇÕES | The University of Tokyo |
| ORCID | 0000-0002-4443-4535 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 32 |
| TOTAL DE CITAÇÕES | 39 |
| TOTAL COMO AUTOR | 32 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1995 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 2 |
Identifying age 26 as a threshold in psychosocial risks associated with child maltreatment among first-time mothers
Background Early pregnancy is associated with increased psychosocial vulnerability, which has been linked to factors associated with child maltreatment. However, previous research has predominantly focused on teenagers, and little is known about whether first-time mothers in their early-to-mid twenties also exhibit elevated psychosocial risks. This observational cross-sectional study aimed to determine whether psychosocial risk factors associated…
Loneliness patterns across time and subsequent risk of psychotic experiences, depression, anxiety, and diminished well‐being in adolescents
BACKGROUND: Evidence on the association between loneliness and psychotic experiences in adolescents remains limited. Moreover, loneliness has typically been assessed at a single time point, which fails to capture its dynamic nature. We hypothesized that persistent loneliness, assessed across repeated measures, would be associated with psychotic experiences and other mental health problems. METHODS: Using longitudinal data from 3,171 participants …
Contact Experiences of Adolescents and Family Members Are Associated With Decrease of Personal Stigma But Increase of Perceived Stigma
BACKGROUND: Adolescents' mental health-related public stigma, encompassing personal and perceived stigma, may vary according to family dynamics and personal or familial experiences. This study aimed to investigate the association between adolescents' and their family members' stigma, specifically whether adolescents' personal and perceived stigma are associated with other members' experiences, particularly contact experiences. METHODS: From a pop…
The silent crisis in girls' mental health
Adolescent psychotic experiences before and during the Covid ‐19 pandemic
BACKGROUND: Understanding the etiology of psychosis is essential to the development of preventive interventions. The COVID-19 pandemic provides a rare natural experiment that can expand our understanding of the role of social factors in the trajectories and etiology of psychosis across adolescence, particularly in Tokyo where the prevalence of actual COVID-19 infection remained low. We hypothesized that the likelihood of self-reporting psychotic …
Informal Caregiving in Adolescents from 10 to 16 Years Old
There is growing evidence of the impact of informal caregiving on adolescent mental health, and its role is often hidden unintentionally or intentionally, which may hamper early identification and support for young informal caregivers. However, the quantitative evidence regarding household factors relating to informal caregiving has mostly been based on cross-sectional findings. This study examines the longitudinal associations between household …
Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
Sensory prediction is considered an important element of mismatch negativity (MMN) whose reduction is well known in patients with schizophrenia. Omission MMN is a variant of the MMN which is elicited by the absence of a tone previously sequentially presented. Omission MMN can eliminate the effects of sound differences in typical oddball paradigms and affords the opportunity to identify prediction-related signals in the brain. Auditory predictions…
Self-Reported Maternal Parenting Stress From 9 m Is Longitudinally Associated With Child ADHD Symptoms at Age 12
We identified associations between parenting stress at 9-10, 18 and 36 m after childbirth and child ADHD symptoms at 12 years old. Self-reported parenting stress data may have utility as an early indicator for ADHD risk. Participation in early-life health checks, assessment of parenting stress, and tailoring support to family needs should be promoted for early identification and intervention for ADHD
Being Praised for Prosocial Behaviors Longitudinally Reduces Depressive Symptoms in Early Adolescents
Being praised for prosocial behavior rather than objective prosocial behavior at 10 years of age predicted lower depressive symptoms 2 years later. Praise for adolescents' prosocial behavior can be encouraged to prevent depression
Migration and psychotic experiences in the Tokyo Teen Cohort
The findings suggest that migrant status is associated with increased likelihood of psychotic experiences at age 10 in Tokyo, Japan. Future prospective research should explore social exclusion as a potential underlying mechanism and can further clarify the protective role of IQ and related factors
Eye Movement Abnormalities in Major Depressive Disorder
Background: Despite their high lifetime prevalence, major depressive disorder (MDD) is often difficult to diagnose, and there is a need for useful biomarkers for the diagnosis of MDD. Eye movements are considered a non-invasive potential biomarker for the diagnosis of psychiatric disorders such as schizophrenia. However, eye movement deficits in MDD remain unclear. Thus, we evaluated detailed eye movement measurements to validate its usefulness a…
Detailed Postmortem Profiling of Inflammatory Mediators Expression Revealed Post-inflammatory Alternation in the Superior Temporal Gyrus of Schizophrenia
Recent studies have lent support to the possibility that inflammation is associated with the pathology of schizophrenia. In the study of measurement of inflammatory mediators, which are markers of inflammation, elevated inflammatory cytokine levels in the brain and blood have been reported in patients with schizophrenia. Several postmortem brain studies have also reported changes in the expression of inflammatory cytokines. However, it is not cle…
Longitudinal Bidirectional Relationships Between Maternal Depressive/Anxious Symptoms and Children's Tic Frequency in Early Adolescence
Background: Previous studies have revealed an association between maternal depressive/anxious symptoms and children's tics. However, the longitudinal relationships between these symptoms remain unclear. We examined the longitudinal relationships between maternal depressive/anxious symptoms and children's tic frequency in early adolescence with a population-based sample. Methods: The participants consisted of 3,171 children and their mothers from …
Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts
Large-scale neuroimaging data acquired and shared by multiple institutions are essential to advance neuroscientific understanding of pathophysiological mechanisms in psychiatric disorders, such as major depressive disorder (MDD). About 75% of studies that have applied machine learning technique to neuroimaging have been based on diagnoses by clinicians. However, an increasing number of studies have highlighted the difficulty in finding a clear as…
Abnormality of Resting-State Functional Connectivity in Major Depressive Disorder
Near-infrared spectroscopy (NIRS) is a functional neuroimaging modality that has advantages in clinical usage. Previous functional magnetic resonance imaging (fMRI) studies have found that the resting-state functional connectivity (RSFC) of the default mode network (DMN) is increased, while the RSFC of the cognitive control network (CCN) is reduced in patients with major depressive disorder (MDD) compared with healthy controls. This study tested …
Assessing the hierarchy of personal values among adolescents
INTRODUCTION: For assessing personal values, the rating scale method may not adequately reflect the hierarchical structure of personal values and tends to be influenced by response style bias. The paired comparison method is considered a promising alternative approach, because it engages comparative judgment and may reduce response style biases. The present study aimed to compare these two methods for assessing the hierarchy of personal values am…
Development of the Brief Personal Values Inventory for Sense of Values
The Portrait Values Questionnaire (PVQ) is a widely used questionnaire for assessing sense of values; however, it is difficult to apply for children and adolescents. Therefore, the present study aimed to develop a questionnaire for sense of values, called the Brief Personal Values Inventory (BPVI), consisting of simple questions and fewer items compared to the PVQ. We first created 12 items for the BPVI and then tested criterion‐related validity …
Living in temporary housing and later psychological distress after the Great East Japan Earthquake of 2011
Living in temporary housing is a risk factor for psychological distress after a natural disaster. As temporary housing is an essential resource for those affected by disasters, investigation of factors which potentially mediate living in temporary housing and psychological distress is needed. This is a cohort study in general population of areas affected by the Great East Japan Earthquake in 2011. Data were obtained from self-report questionnaire…
Bi-Directional Relationships Between Psychological Symptoms and Environmental Factors in Early Adolescence
By using the newly introduced methodology, our results were partly consistent with previous literature. Further studies are needed to validate this methodology and accelerate the findings regarding the emergence of psychological symptoms and the impact of environmental factors from childhood to early adolescence
Spatiotemporal Differentiation of MMN From N1 Adaptation
Auditory mismatch negativity (MMN) is an electrophysiological response to a deviation from regularity. This response is considered pivotal to understanding auditory processing, particularly in the pre-attentive phase. However, previous findings suggest that MMN is a product of N1 adaptation/enhancement, which reflects lower-order auditory processing. The separability of these two components remains unclear and is considered an important issue in …
Mismatch Negativity Predicts Remission and Neurocognitive Function in Individuals at Ultra-High Risk for Psychosis
Our findings indicate that dMMN and fMMN predicted remission and neurocognitive function, respectively, in individuals at UHR, which suggests that there are both promising biomarker candidates for predicting prognosis in individuals at UHR
Translatability of Scalp EEG Recordings of Duration-Deviant Mismatch Negativity Between Macaques and Humans
Mismatch negativity (MMN) is a negative deflection of the auditory event-related potential (ERP) elicited by an abrupt change in a sound presented repeatedly. In patients with schizophrenia, MMN is consistently reduced, which makes it a promising biomarker. A non-human primate (NHP) model of MMN based on scalp electroencephalogram (EEG) recordings can provide a useful translational tool, given the high structural homology of the prefrontal and au…
Dog and Cat Ownership Predicts Adolescents’ Mental Well-Being
A potential association between pet ownership and mental well-being is suggested, but there is a shortage of high-quality longitudinal studies that consider probable differences among different species. We aimed to examine whether ownership of the most popular pets (dogs and cats) would predict mental well-being. The Tokyo Teen Cohort (TTC), a prospective population-based birth cohort study, had dog and cat ownership data at age 10 and mental wel…
Anatomical Templates of the Midbrain Ventral Tegmental Area and Substantia Nigra for Asian Populations
Increasing evidence shows that the midbrain dopaminergic system is involved in various functions. However, details of the role of the midbrain dopaminergic system in these functions are still to be determined in humans. Considering that the ventral tegmental area (VTA) and substantia nigra (SN) in the midbrain are the primary dopamine producers, creating reliable anatomical templates of the VTA and SN through neuroimaging studies would be useful …
Trends in psychological distress and alcoholism after The Great East Japan Earthquake of 2011
Psychological distress deteriorated 2 years after the huge natural disaster, compared with 1 year after the disaster. Long-term mental health care is needed for those affected by natural disasters, particularly those who have suffered loss
Tooth wear and the ?design? of the human dentition
Worn, flat occlusal surfaces and anterior edge-to-edge occlusion are ubiquitous among the dentitions of prehistoric humans. The concept of attritional occlusion was proposed in the 1950s as a hypothesis to explain these characteristics. The main aspects of this hypothesis are: 1) the dentitions of ancient populations in heavy-wear environments were continuously and dynamically changing owing to life-long attritional tooth reduction and compensato…
Comparative Study of Vertica1 Sections of the Jomon and Modern Japanese Mandibles
The purposes of this study are to compare the characteristics of mandibular internal structures between Neolithic Jomon and modern Japanese, and to investigate the relationship between internal structures of the mandible and the standing position of the teeth in both populations with the use of CT scanning. The data for this study were obtained from 40 male Japanese and 39 male Jomon dry adult skulls housed in the Department of Anthropology and P…
Morphological Characteristics of Vertical Sections of the Mandible Obtained by CT Scanning
The external structure of the mandible is not only under the control of genetic factors, but is also influenced by biomechanical factors such as the masticatory muscles. As is well known, one of the characteristics of the morphology of the mandible which represents the influence of these factors is the gonial angle. It varies from a low angle with strong masseter development to a high angle with reduced muscle activity. The aims of this study wer…
Fourier Analysis of Dental Arch Morphology in South Australian Twins
Our aims were to assess the suitability of Fourier harmonics in describing dental arch form in South Australian twins and to estimate the contribution of genetic factors to observed variability. Dental casts of 37 monozygous (MZ) and 19 dizygous (DZ) twin pairs were selected, all subjects being male Caucasians with minimal dental crowding and no history of orthodontic treatment. There were no significant differences between the groups in any of t…
Morphological Characteristics of Vertical Sections of the Mandible Obtained by CT Scanning
The external structure of the mandible is not only under the control of genetic factors, but is also influenced by biomechanical factors such as the masticatory muscles. As is well known, one of the characteristics of the morphology of the mandible which represents the influence of these factors is the gonial angle. It varies from a low angle with strong masseter development to a high angle with reduced muscle activity. The aims of this study wer…
Comparative study of craniofacial morphology and bite force in Fijians and Japanese
An anthropological survey was conducted in Fiji in 1994 and 1995 to study dental arch form, craniofacial morphology, and bite force of Fijians. Measurements were obtained from dental casts, cephalograms, and thin pressure-sensitive sheets (Dental Prescale®) for bite force analysis. Results were compared with those of Japanese. In every direction, the size of the dental arch in Fijians was larger than in Japanese. Fijians displayed longer palates,…
Comparative study of craniofacial morphology and bite force in Fijians and Japanese
An anthropological survey was conducted in Fiji in 1994 and 1995 to study dental arch form, craniofacial morphology, and bite force of Fijians. Measurements were obtained from dental casts, cephalograms, and thin pressure-sensitive sheets (Dental Prescale®) for bite force analysis. Results were compared with those of Japanese. In every direction, the size of the dental arch in Fijians was larger than in Japanese. Fijians displayed longer palates,…
Comparative Study of Vertica1 Sections of the Jomon and Modern Japanese Mandibles
The purposes of this study are to compare the characteristics of mandibular internal structures between Neolithic Jomon and modern Japanese, and to investigate the relationship between internal structures of the mandible and the standing position of the teeth in both populations with the use of CT scanning. The data for this study were obtained from 40 male Japanese and 39 male Jomon dry adult skulls housed in the Department of Anthropology and P…
Short and Broad Dental Arch in Papua New Guinea Highlanders
Dental arch sizes and shapes of Papua New Guinea (PNG) Highlanders (Wabag, Enga Province, 26 males and 26 females) were measured using photographs of dental casts and compared with those of five populations in the Pacific region (Fiji, Samoa, Kiribati, Australia, Japan). The dental arch breadths of the Wabag males and females were the largest among the six groups. The Wabag males had the shortest lengths and the Wabag females were in the middle r…
Tooth wear and the ?design? of the human dentition
Worn, flat occlusal surfaces and anterior edge-to-edge occlusion are ubiquitous among the dentitions of prehistoric humans. The concept of attritional occlusion was proposed in the 1950s as a hypothesis to explain these characteristics. The main aspects of this hypothesis are: 1) the dentitions of ancient populations in heavy-wear environments were continuously and dynamically changing owing to life-long attritional tooth reduction and compensato…
Trends in psychological distress and alcoholism after The Great East Japan Earthquake of 2011
Psychological distress deteriorated 2 years after the huge natural disaster, compared with 1 year after the disaster. Long-term mental health care is needed for those affected by natural disasters, particularly those who have suffered loss
Anatomical Templates of the Midbrain Ventral Tegmental Area and Substantia Nigra for Asian Populations
Increasing evidence shows that the midbrain dopaminergic system is involved in various functions. However, details of the role of the midbrain dopaminergic system in these functions are still to be determined in humans. Considering that the ventral tegmental area (VTA) and substantia nigra (SN) in the midbrain are the primary dopamine producers, creating reliable anatomical templates of the VTA and SN through neuroimaging studies would be useful …
Assessing the hierarchy of personal values among adolescents
INTRODUCTION: For assessing personal values, the rating scale method may not adequately reflect the hierarchical structure of personal values and tends to be influenced by response style bias. The paired comparison method is considered a promising alternative approach, because it engages comparative judgment and may reduce response style biases. The present study aimed to compare these two methods for assessing the hierarchy of personal values am…
Development of the Brief Personal Values Inventory for Sense of Values
The Portrait Values Questionnaire (PVQ) is a widely used questionnaire for assessing sense of values; however, it is difficult to apply for children and adolescents. Therefore, the present study aimed to develop a questionnaire for sense of values, called the Brief Personal Values Inventory (BPVI), consisting of simple questions and fewer items compared to the PVQ. We first created 12 items for the BPVI and then tested criterion‐related validity …
Living in temporary housing and later psychological distress after the Great East Japan Earthquake of 2011
Living in temporary housing is a risk factor for psychological distress after a natural disaster. As temporary housing is an essential resource for those affected by disasters, investigation of factors which potentially mediate living in temporary housing and psychological distress is needed. This is a cohort study in general population of areas affected by the Great East Japan Earthquake in 2011. Data were obtained from self-report questionnaire…
Bi-Directional Relationships Between Psychological Symptoms and Environmental Factors in Early Adolescence
By using the newly introduced methodology, our results were partly consistent with previous literature. Further studies are needed to validate this methodology and accelerate the findings regarding the emergence of psychological symptoms and the impact of environmental factors from childhood to early adolescence
Spatiotemporal Differentiation of MMN From N1 Adaptation
Auditory mismatch negativity (MMN) is an electrophysiological response to a deviation from regularity. This response is considered pivotal to understanding auditory processing, particularly in the pre-attentive phase. However, previous findings suggest that MMN is a product of N1 adaptation/enhancement, which reflects lower-order auditory processing. The separability of these two components remains unclear and is considered an important issue in …
Mismatch Negativity Predicts Remission and Neurocognitive Function in Individuals at Ultra-High Risk for Psychosis
Our findings indicate that dMMN and fMMN predicted remission and neurocognitive function, respectively, in individuals at UHR, which suggests that there are both promising biomarker candidates for predicting prognosis in individuals at UHR
Translatability of Scalp EEG Recordings of Duration-Deviant Mismatch Negativity Between Macaques and Humans
Mismatch negativity (MMN) is a negative deflection of the auditory event-related potential (ERP) elicited by an abrupt change in a sound presented repeatedly. In patients with schizophrenia, MMN is consistently reduced, which makes it a promising biomarker. A non-human primate (NHP) model of MMN based on scalp electroencephalogram (EEG) recordings can provide a useful translational tool, given the high structural homology of the prefrontal and au…
Dog and Cat Ownership Predicts Adolescents’ Mental Well-Being
A potential association between pet ownership and mental well-being is suggested, but there is a shortage of high-quality longitudinal studies that consider probable differences among different species. We aimed to examine whether ownership of the most popular pets (dogs and cats) would predict mental well-being. The Tokyo Teen Cohort (TTC), a prospective population-based birth cohort study, had dog and cat ownership data at age 10 and mental wel…
Eye Movement Abnormalities in Major Depressive Disorder
Background: Despite their high lifetime prevalence, major depressive disorder (MDD) is often difficult to diagnose, and there is a need for useful biomarkers for the diagnosis of MDD. Eye movements are considered a non-invasive potential biomarker for the diagnosis of psychiatric disorders such as schizophrenia. However, eye movement deficits in MDD remain unclear. Thus, we evaluated detailed eye movement measurements to validate its usefulness a…
Detailed Postmortem Profiling of Inflammatory Mediators Expression Revealed Post-inflammatory Alternation in the Superior Temporal Gyrus of Schizophrenia
Recent studies have lent support to the possibility that inflammation is associated with the pathology of schizophrenia. In the study of measurement of inflammatory mediators, which are markers of inflammation, elevated inflammatory cytokine levels in the brain and blood have been reported in patients with schizophrenia. Several postmortem brain studies have also reported changes in the expression of inflammatory cytokines. However, it is not cle…
Longitudinal Bidirectional Relationships Between Maternal Depressive/Anxious Symptoms and Children's Tic Frequency in Early Adolescence
Background: Previous studies have revealed an association between maternal depressive/anxious symptoms and children's tics. However, the longitudinal relationships between these symptoms remain unclear. We examined the longitudinal relationships between maternal depressive/anxious symptoms and children's tic frequency in early adolescence with a population-based sample. Methods: The participants consisted of 3,171 children and their mothers from …
Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts
Large-scale neuroimaging data acquired and shared by multiple institutions are essential to advance neuroscientific understanding of pathophysiological mechanisms in psychiatric disorders, such as major depressive disorder (MDD). About 75% of studies that have applied machine learning technique to neuroimaging have been based on diagnoses by clinicians. However, an increasing number of studies have highlighted the difficulty in finding a clear as…
Abnormality of Resting-State Functional Connectivity in Major Depressive Disorder
Near-infrared spectroscopy (NIRS) is a functional neuroimaging modality that has advantages in clinical usage. Previous functional magnetic resonance imaging (fMRI) studies have found that the resting-state functional connectivity (RSFC) of the default mode network (DMN) is increased, while the RSFC of the cognitive control network (CCN) is reduced in patients with major depressive disorder (MDD) compared with healthy controls. This study tested …
Prediction-Related Frontal-Temporal Network for Omission Mismatch Activity in the Macaque Monkey
Sensory prediction is considered an important element of mismatch negativity (MMN) whose reduction is well known in patients with schizophrenia. Omission MMN is a variant of the MMN which is elicited by the absence of a tone previously sequentially presented. Omission MMN can eliminate the effects of sound differences in typical oddball paradigms and affords the opportunity to identify prediction-related signals in the brain. Auditory predictions…
Self-Reported Maternal Parenting Stress From 9 m Is Longitudinally Associated With Child ADHD Symptoms at Age 12
We identified associations between parenting stress at 9-10, 18 and 36 m after childbirth and child ADHD symptoms at 12 years old. Self-reported parenting stress data may have utility as an early indicator for ADHD risk. Participation in early-life health checks, assessment of parenting stress, and tailoring support to family needs should be promoted for early identification and intervention for ADHD
Being Praised for Prosocial Behaviors Longitudinally Reduces Depressive Symptoms in Early Adolescents
Being praised for prosocial behavior rather than objective prosocial behavior at 10 years of age predicted lower depressive symptoms 2 years later. Praise for adolescents' prosocial behavior can be encouraged to prevent depression
Medicine (25 obras) · Psychology (21 obras) · Clinical Psychology (11 obras) · Psychiatry (11 obras) · Population (10 obras) · Child and Adolescent Psychosocial and Emotional Development (8 obras) · Clinical Psychology (8 obras) · Cohort (8 obras) · Developmental psychology (8 obras) · Neuroscience (8 obras)