Life Course Socioeconomic Status and Longitudinal Accumulation of Allostatic Load in Adulthood

Multi-Ethnic Study of Atherosclerosis

Dados Bibliográficos

ID11023331
AutoresSharon Stein Merkin (0000-0002-7468-0948, At the time of this study, Sharon Stein Merkin, Arun Karlamangla, and Teresa E. Seeman were with the Division of Geriatrics, Geffen School of Medicine, University of California, Los Angeles. Ana V. Diez Roux was with the Department of Epidemiology, University of Michigan, Ann Arbor. Sandi Shrager was with the Department of Biostatistics, University of Washington School of Public Health, Seattle.), Arun Karlamangla (At the time of this study, Sharon Stein Merkin, Arun Karlamangla, and Teresa E. Seeman were with the Division of Geriatrics, Geffen School of Medicine, University of California, Los Angeles. Ana V. Diez Roux was with the Department of Epidemiology, University of Michigan, Ann Arbor. Sandi Shrager was with the Department of Biostatistics, University of Washington School of Public Health, Seattle.), Arun S Karlamangla (0000-0003-2293-6064, University of Washington), Ana V Diez Roux (0000-0001-9658-7050, At the time of this study, Sharon Stein Merkin, Arun Karlamangla, and Teresa E. Seeman were with the Division of Geriatrics, Geffen School of Medicine, University of California, Los Angeles. Ana V. Diez Roux was with the Department of Epidemiology, University of Michigan, Ann Arbor. Sandi Shrager was with the Department of Biostatistics, University of Washington School of Public Health, Seattle.), Sandi Shrager (At the time of this study, Sharon Stein Merkin, Arun Karlamangla, and Teresa E. Seeman were with the Division of Geriatrics, Geffen School of Medicine, University of California, Los Angeles. Ana V. Diez Roux was with the Department of Epidemiology, University of Michigan, Ann Arbor. Sandi Shrager was with the Department of Biostatistics, University of Washington School of Public Health, Seattle.), Teresa Seeman (0000-0001-8583-4239, At the time of this study, Sharon Stein Merkin, Arun Karlamangla, and Teresa E. Seeman were with the Division of Geriatrics, Geffen School of Medicine, University of California, Los Angeles. Ana V. Diez Roux was with the Department of Epidemiology, University of Michigan, Ann Arbor. Sandi Shrager was with the Department of Biostatistics, University of Washington School of Public Health, Seattle.), Teresa E Seeman
Ano2014
Volume104
Fascículo4
Páginase48-e55
Data de publicação2014-04-01
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoAmerican Journal of Public Health (JOURNAL)
Identificadores do periódicoISSN: 0090-0036 • E-ISSN: 1541-0048
EditoraAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2013.301841
PMID24524526
PMCIDPMC4025706
OpenAlexW1984741136
IdiomaEN
Citações recebidas18
Referências citadas29

Objectives. We examined the association of childhood and adult socioeconomic status with longitudinal change in allostatic load (AL), a measure of biological dysfunction. Methods. The study sample included 6135 participants from the Multi-Ethnic Study of Atherosclerosis, aged 45 to 84 years, recruited in 2000 from 6 US counties; 3 follow-up examinations took place through September 2011. We calculated standardized scores for several metabolic and cardiovascular components relative to accepted clinical cut points for “higher risk” and then summed them to create an overall index of AL. We used mixed effects growth curve models to assess the relationship between socioeconomic status and AL as a linear function of time passed since the baseline examination; we included random effects for the intercept and slope. Results. Among those with lower baseline AL ( Conclusions. The relationship between socioeconomic status and patterns of change in health parameters may vary over time and with the accumulation of biological risk

Allostatic load · Developmental psychology · Environmental health · Ethnic group · Life course approach · Longitudinal study · Pathology · Population · Socioeconomic status · Birth, Development, and Health · Demography · Diabetes, Cardiovascular Risks, and Lipoproteins · Health disparities and outcomes · Medicine · Psychology · Gerontology