Characteristics of Health Information Gatherers, Disseminators, and Blockers Within Families at Risk of Hereditary Cancer

Implications for Family Health Communication Interventions

Dados Bibliográficos

ID11024342
AutoresLaura M Koehly (0000-0003-4588-2898, Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...), June A Peters (0000-0003-4077-8389, Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...), R Kenen (0000-0002-2821-9261, Department of Health and Human Services), Lindsey M Hoskins (Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...), Lindsey Hoskins (Department of Health and Human Services), Anne L Ersig (0000-0002-4169-8287, Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...), Natalia R Kuhn (Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...), Natalia Kühn (Department of Health and Human Services), Jennifer T Loud (0000-0002-2049-5712, Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...), Mark H Greene (0000-0003-1852-9239, Laura M. Koehly is with the Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes Health, Department of Health and Human Services, Bethesda, MD. June A. Peters, Lindsey M. Hoskins, Jennifer T. Loud, and Mark H. Greene are with the Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD. Regina Kenen is with the Department of...)
Ano2009
Volume99
Fascículo12
Páginas2203-2209
Data de publicação2009-12-01
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoAmerican Journal of Public Health (JOURNAL)
Identificadores do periódicoISSN: 0090-0036 • E-ISSN: 1541-0048
EditoraAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2008.154096
PMID19833996
PMCIDPMC2775786
OpenAlexW2132034058
IdiomaEN
Citações recebidas27
Referências citadas49

Objectives. Given the importance of the dissemination of accurate family history to assess disease risk, we characterized the gatherers, disseminators, and blockers of health information within families at high genetic risk of cancer. Methods. A total of 5466 personal network members of 183 female participants of the Breast Imaging Study from 124 families with known mutations in the BRCA1/2 genes (associated with high risk of breast, ovarian, and other types of cancer) were identified by using the Colored Eco-Genetic Relationship Map (CEGRM). Hierarchical nonlinear models were fitted to characterize information gatherers, disseminators, and blockers. Results. Gatherers of information were more often female (P Conclusions. Our results provide insight into which family members may, within a family-based intervention, effectively gather family risk information, disseminate information, and encourage discussions regarding shared family risk

Breast cancer · Cancer · Disease · Family history · Family medicine · First-degree relatives · Intervention (counseling) · Nuclear family · Psychiatry · Psychological intervention · BRCA gene mutations in cancer · Demography · Genetic Associations and Epidemiology · Global Cancer Incidence and Screening · Internal Medicine · Medicine