Serum dehydroepiandrosterone sulphate and pubertal development in Chinese girls

Dados Bibliográficos

ID13921981
AutoresBing Cai (0000-0002-3632-9866, Shanghai Medical College of Fudan University, autor correspondente), C Bing, Shan Xu (0000-0002-2251-8682, Shanghai Medical College of Fudan University), S E Xu, G D Zhang (Shanghai Medical College of Fudan University), W Y Wang (Shanghai Medical College of Fudan University)
Ano1988
Volume15
Fascículo6
Páginas421-429
Data de publicação1988-01-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoAnnals of Human Biology (JOURNAL)
Identificadores do periódicoISSN: 0301-4460 • E-ISSN: 1464-5033
EditoraInforma (PUBLISHER • GB)
DOI10.1080/03014468800000022
PMID2977935
OpenAlexW2005433684
IdiomaEN
Citações recebidas1
Referências citadas17

Serum dehydroepiandrosterone sulphate (DHEAS), estradiol (E2), luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured by radioimmunoassay in 170 healthy school girls from 7-16 years old. Blood samples from postmenarcheal girls were taken on days 6-10 of the menstrual cycle. Bone age, height, weight, breast and pubic hair development were also investigated. Of the four hormones measured, serum DHEAS displayed the earliest elevation, at 7 years and upwards. A significant DHEAS increment at chronological age 13 years was observed. Girls with earlier menarche had higher DHEAS level than girls having later menarche. Serum DHEAS levels also correlated with bone age, height, weight, subcutaneous fat and pubertal stages. The results suggest that adrenal androgen might be involved in the initiation of puberty and female maturation

Androgen · Biology · Body height · Body weight · Dehydroepiandrosterone · Dehydroepiandrosterone sulfate · Hormone · Sociology · Demography · Hormonal and reproductive studies · Hypothalamic control of reproductive hormones · Medicine · Menstrual Health and Disorders · Endocrinology · Internal Medicine · Physiology