Qing'e Pill rectifies bone homeostasis imbalance in diabetic osteoporosis via the AGE/Rage pathway
A network pharmacology analysis and multi-omics validation
Dados Bibliográficos
| ID | 14728205 |
|---|---|
| Autores | Yingjie Wang (0000-0003-0920-9305, University of Science and Technology of China, autor correspondente), Yang Yao (0000-0002-7240-2688, University of Science and Technology of China), Yao Yang (0000-0003-3611-2859), Yuan Chen (0000-0002-7069-1631, University of Science and Technology of China), Yanling Zhou (0000-0002-3966-4424, University of Science and Technology of China), Siming Zhang (0000-0003-3008-8392, University of Science and Technology of China), Wanbo Zhu (0000-0003-3457-3432, Shanghai Sixth People's Hospital), Xianzuo Zhang (0000-0002-6432-7745, University of Science and Technology of China), Junchen Zhu (0009-0002-1587-8185, Anhui Medical University) |
| Ano | 2025 |
| Volume | 348 |
| Páginas | 119816 |
| Data de publicação | 2025-05-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores do periódico | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editora | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.119816 |
| PMID | 40245968 |
| OpenAlex | W4409472685 |
| Idioma | EN |
| Referências citadas | 35 |
QEP enhance osteogenesis and angiogenesis via the AGE/RAGE signaling pathway, offering anti-inflammatory, hypoglycemic, and anti-osteoporotic effects. These results support the potential clinical application of QEP in managing diabetic osteoporosis
Bioinformatics · Biology · Diabetes mellitus · Omics · Osteoporosis · Pill · Bone health and osteoporosis research · Bone Metabolism and Diseases · Medicine · Osteoarthritis Treatment and Mechanisms · Endocrinology · Internal Medicine · Pharmacology
| Velocidade de citação | historical |
|---|---|
| Altamente citado | Não |