Network pharmacology analysis of the regulatory effects and mechanisms of Alae on sow reproduction in vivo and in vitro
Dados Bibliográficos
| ID | 14733282 |
|---|---|
| Autores | Linlu Zhao (0009-0008-6375-1836, Guangdong Ocean University), Jin Zhang (0000-0002-1374-598X, Guangdong Ocean University), Jieyi He (0000-0003-4066-8016, Guangdong Ocean University), Mengru Guo (Guangdong Ocean University), Huining Wu (Guangdong Ocean University), Xingbin Ma (0000-0003-2874-8312, Guangdong Ocean University), Zhichao Yu (0000-0001-9172-2778, Guangdong Ocean University), Yanhong Yong, Yin Yong (Guangdong Ocean University), Youquan Li (0000-0002-9108-390X, Guangdong Ocean University), Xianghong Ju (0000-0001-8822-484X, Guangdong Ocean University), Xiaoxi Liu (0000-0001-5917-5495, Guangdong Ocean University, autor correspondente) |
| Ano | 2024 |
| Volume | 334 |
| Páginas | 118525 |
| Data de publicação | 2024-11-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores do periódico | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editora | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2024.118525 |
| PMID | 38992402 |
| OpenAlex | W4400438833 |
| Idioma | EN |
| Referências citadas | 82 |
Dministration of ALAE significantly increased the total number of piglets born, the numbers of live and healthy litters and decreased the number of stillbirths through improving placental structure, attenuating inflammatory response, modulating placental angiogenesis and growth factor receptors in sows. The improvement of reproductive ability may be related to activation of the EGFR-PI3K-AKT1 pathway in PEECs. Moreover, ALAE maybe involved in modulation of estrogen receptors, apoptotic factors, and cell cycle proteins
Angelica sinensis · Astragalus · Biological activity · Biology · Botany · Eucommia ulmoides · Glycyrrhiza · Glycyrrhiza uralensis · In vitro · In vivo · Medicinal plants · Pharmacognosy · Phytotherapy · Reproduction · Traditional Chinese medicine · Traditional medicine · Ginseng Biological Effects and Applications · Medicinal Plant Pharmacodynamics Research · Medicine · Traditional Chinese Medicine Analysis · Biochemistry · Biotechnology · Ecology
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| Velocidade de citação | historical |
|---|---|
| Altamente citado | Não |