Early administration of Wumei Wan inhibit myeloid-derived suppressor cells via PI3K/Akt pathway and amino acids metabolism to prevent colitis-associated colorectal cancer
Dados Bibliográficos
WMW can effectively prevent the occurrence and development of CAC, especially in the initial stage. WMW can reduce the immune infiltration of MDSCs in the early stage. Early intervention of WMW can improve the metabolic disorder caused by AOM + DSS, especially correct the amino acid metabolism. PI3K/Akt signaling pathway was inhabited in early administration of WMW, which can regulate the amplification and function of MDSCs
Cancer · Colitis · Colorectal cancer · Medical prescription · Pathology · PI3K/AKT/mTOR pathway · Protein kinase B · Signal transduction · Traditional Chinese medicine · Chemistry · Immune Cell Function and Interaction · Immune cells in cancer · Medicine · NF-κB Signaling Pathways · Biochemistry · Cancer Research · Internal Medicine · Pharmacology
Traditional Chinese Medicine formulas-based interventions on colorectal carcinoma prevention
Effect of traditional Chinese medicine on disturbances of untargeted metabolomics in ulcerative colitis
Wumei Wan remodels the tumor immune microenvironment via the Ido1-KYN-AHR axis in AOM/DSS-induced colorectal cancer model
Traditional Mongolian medicine Batri-7 exhibits chemopreventive activity in colitis-associated colorectal cancer through microbiota modulation and NLRP3 inflammasome targeting
Erchen decoction alleviates silicosis by attenuating ferroptosis and fibrosis in alveolar macrophages via modulating the P53/HMOX1 pathway
| Citações por ano | 5 |
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| Intervalo de citações | 2025 - 2026 (2) |
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