Mechanisms of pancreatic tumor suppression mediated by Xiang-lian pill
An integrated in silico exploration and experimental validation
Dados Bibliográficos
| ID | 14735147 |
|---|---|
| Autores | Juying Jiao (0000-0003-1413-7190, Fudan University Shanghai Cancer Center), Chien-shan Cheng, Chien‐shan Cheng (0000-0003-4885-6759, Shanghai Medical College of Fudan University), Panling Xu (0000-0003-1592-5527, First Affiliated Hospital of Anhui Medical University), Peiwen Yang (0000-0002-4351-3151, Fudan University Shanghai Cancer Center), Ke Zhang (0000-0002-1841-9016, Shanghai Medical College of Fudan University), Yanhua Jing (Fudan University Shanghai Cancer Center), Zhen Chen (0009-0006-7688-3040, Fudan University Shanghai Cancer Center, autor correspondente) |
| Ano | 2022 |
| Volume | 298 |
| Páginas | 115586 |
| Data de publicação | 2022-11-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores do periódico | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editora | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2022.115586 |
| PMID | 35931303 |
| OpenAlex | W4289527016 |
| Idioma | EN |
| Citações recebidas | 3 |
| Referências citadas | 30 |
Xiang-lian pill mainly regulates inflammation, apoptosis, metastasis, and metabolism to exert an antitumor effect. The main active ingredients in Xiang-lian pill exhibit antitumor roles through directly binding to key targets in pancreatic cancer. PTGS2 mediated MEK/ERK inhibition by rutaecarpine represents a key therapeutic mechanism of Xiang-lian pill
Biology · Cancer · In vivo · Pancreatic cancer · Pill · Traditional medicine · Berberine and alkaloids research · Cancer therapeutics and mechanisms · Colorectal Cancer Treatments and Studies · Medicine · Internal Medicine · Pharmacology
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| Obras citantes distintas | 3 |
|---|---|
| Citações por ano | 1 |
| Intervalo de citações | 2023 - 2025 (3) |
| Velocidade de citação | recent |
| Altamente citado | Não |
| Tipos de citação | Neutras: 3 |