Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice
Dados Bibliográficos
Our findings regarding the anti-inflammatory effect of PO and the underlying molecular mechanisms help justify the use of Pogostemon cablin in Chinese medicine for the treatment of inflammatory diseases. More importantly, the results also render PO a promising anti-inflammatory agent worthy of further development into a pharmaceutical drug for the treatment of septic shock
Biology · In vitro · In vivo · Inflammation · Lipopolysaccharide · MAPK/ERK pathway · Mechanism of Action · p38 mitogen-activated protein kinases · Phosphorylation · Pogostemon · Proinflammatory cytokine · Traditional medicine · Tumor necrosis factor alpha · Chemistry · Ethnobotanical and Medicinal Plants Studies · Ginger and Zingiberaceae research · Medicine · Phytochemistry and biological activity of medicinal plants · Biochemistry · Immunology · Pharmacology
Protective effect of pogostone on murine norovirus infected-RAW264.7 macrophages through inhibition of NF-κB/NLRP3-dependent pyroptosis
Anti-inflammatory effects of three withanolides isolated from Physalis angulata L. in LPS-activated RAW 264.7 cells through blocking NF-κB signaling pathway
Huang-Lian-Jie-Du extract ameliorates atopic dermatitis-like skin lesions induced by 2,4-dinitrobenzene in mice via suppression of Mapks and NF-κB pathways
Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells
| Citações por ano | 0,44 |
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| Intervalo de citações | 2017 - 2021 (5) |
| Altamente citado | Não |