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Integrating hippocampal metabolomics and network pharmacology deciphers the antidepressant mechanisms of Xiaoyaosan

Dados Bibliográficos

ID14744646
AutoresXiaojie Liu (0009-0002-1701-1542, Shanxi University, autor correspondente), Fuxiao Wei (Shanxi University), Huanle Liu (0000-0002-4910-3698, Shanxi University), Sijun Zhao (Shanxi University), Guanhua Du (0000-0002-6896-0847, Chinese Academy of Medical Sciences & Peking Union Medical College), Xuemei Qin (0000-0002-0020-3364, Shanxi University, autor correspondente)
Ano2021
Volume268
Páginas113549
Data de publicação2021-03-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Ethnopharmacology (JOURNAL)
Identificadores do periódicoISSN: 0378-8741 • E-ISSN: 1872-7573
EditoraElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2020.113549
PMID33152435
OpenAlexW3097511852
IdiomaEN
Citações recebidas3
Referências citadas30

Amino acid · Antidepressant · Glutamine · Hippocampus · PI3K/AKT/mTOR pathway · Signal transduction · Chemistry · Medicine · Metabolomics and Mass Spectrometry Studies · Stress Responses and Cortisol · Tryptophan and brain disorders · Biochemistry · Endocrinology · Pharmacology

  • Xiaoyaosan promotes neurotransmitter transmission and alleviates Cums-induced depression by regulating the expression of Oct1 and Oct3 in astrocytes of the prefrontal cortex

    Open Access•Yayun Wu, Lijuan Liu et al.•Journal of Ethnopharmacology•2024

  • A comprehensive study on the regulation of Compound Zaoren Granules on cAMP/CREB signaling pathway and metabolic disorder in Cums-PCPA induced insomnia rats

    Open Access•Zekun Wang, Danting Li et al.•Journal of Ethnopharmacology•2024

  • Xiaoyaosan ameliorates Cums-induced depressive-like and anorexia behaviors in mice via necroptosis related cellular senescence in hypothalamus

    Open Access•Haiyan Jiao, Yingli Fan et al.•Journal of Ethnopharmacology•2024

  • Xiaoyaosan Ameliorates Chronic Immobilization Stress-Induced Depression-Like Behaviors and Anorexia in Rats

    Open Access•Qingyu Ma, Xiaojuan Li et al.•Frontiers in Psychiatry•2019

  • Differential Regulation of DNA Methylation at the CRMP2 Promoter Region Between the Hippocampus and Prefrontal Cortex in a Cums Depression Model

    Open Access•Dan Xiang, Jiawei Xiao et al.•Frontiers in Psychiatry•2020

  • Plasma metabolomics of depressed patients and treatment with Xiaoyaosan based on mass spectrometry technique

    Open Access•Xiaojie Liu, Caichun Liu et al.•Journal of Ethnopharmacology•2020

  • Brain metabonomics study of the antidepressant-like effect of Xiaoyaosan on the Cums-depression rats by 1H NMR analysis

    Open Access•Xiaojie Liu, Xingyu Zheng et al.•Journal of Ethnopharmacology•2019

  • Coniferyl ferulate exerts antidepressant effect via inhibiting the activation of NMDAR-CaMKII-Mapks and mitochondrial apoptotic pathways

    Open Access•Wenxia Gong, Yuzhi Zhou et al.•Journal of Ethnopharmacology•2020

  • Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics

    Open Access•Congcong Chen, Qicai Yin et al.•Journal of Ethnopharmacology•2020

Obras citantes distintas3
Citações por ano1,5
Intervalo de citações2024 - 2024 (1)
Velocidade de citaçãorecent
Altamente citadoNão
Tipos de citaçãoNeutras: 3
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