Integrating hippocampal metabolomics and network pharmacology deciphers the antidepressant mechanisms of Xiaoyaosan
Dados Bibliográficos
| ID | 14744646 |
|---|---|
| Autores | Xiaojie Liu (0009-0002-1701-1542, Shanxi University, autor correspondente), Fuxiao Wei (Shanxi University), Huanle Liu (0000-0002-4910-3698, Shanxi University), Sijun Zhao (Shanxi University), Guanhua Du (0000-0002-6896-0847, Chinese Academy of Medical Sciences & Peking Union Medical College), Xuemei Qin (0000-0002-0020-3364, Shanxi University, autor correspondente) |
| Ano | 2021 |
| Volume | 268 |
| Páginas | 113549 |
| Data de publicação | 2021-03-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores do periódico | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editora | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2020.113549 |
| PMID | 33152435 |
| OpenAlex | W3097511852 |
| Idioma | EN |
| Citações recebidas | 3 |
| Referências citadas | 30 |
Amino acid · Antidepressant · Glutamine · Hippocampus · PI3K/AKT/mTOR pathway · Signal transduction · Chemistry · Medicine · Metabolomics and Mass Spectrometry Studies · Stress Responses and Cortisol · Tryptophan and brain disorders · Biochemistry · Endocrinology · Pharmacology
Xiaoyaosan promotes neurotransmitter transmission and alleviates Cums-induced depression by regulating the expression of Oct1 and Oct3 in astrocytes of the prefrontal cortex
A comprehensive study on the regulation of Compound Zaoren Granules on cAMP/CREB signaling pathway and metabolic disorder in Cums-PCPA induced insomnia rats
Xiaoyaosan ameliorates Cums-induced depressive-like and anorexia behaviors in mice via necroptosis related cellular senescence in hypothalamus
Xiaoyaosan Ameliorates Chronic Immobilization Stress-Induced Depression-Like Behaviors and Anorexia in Rats
Differential Regulation of DNA Methylation at the CRMP2 Promoter Region Between the Hippocampus and Prefrontal Cortex in a Cums Depression Model
Plasma metabolomics of depressed patients and treatment with Xiaoyaosan based on mass spectrometry technique
Brain metabonomics study of the antidepressant-like effect of Xiaoyaosan on the Cums-depression rats by 1H NMR analysis
Coniferyl ferulate exerts antidepressant effect via inhibiting the activation of NMDAR-CaMKII-Mapks and mitochondrial apoptotic pathways
Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics
| Obras citantes distintas | 3 |
|---|---|
| Citações por ano | 1,5 |
| Intervalo de citações | 2024 - 2024 (1) |
| Velocidade de citação | recent |
| Altamente citado | Não |
| Tipos de citação | Neutras: 3 |