Chemsex is not a barrier to self-reported daily PrEP adherence among PROUD study participants

These analyses suggest PrEP remains a feasible and effective HIV prevention method for GBM engaging in chemsex, a practise which is prevalent in this group and has been associated with increased HIV transmission risk

Anal intercourse · Antiretroviral therapy · Drug · Emtricitabine · Family medicine · Human immunodeficiency virus (HIV · Men who have sex with men · Mephedrone · Pre-exposure prophylaxis · Psychiatry · Syphilis · Viral load · Clinical Psychology · Demography · HIV Research and Treatment · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine

• Trajectories of Chemsex Engagement Across Time Among PrEP-Using Men Who Have Sex with Men

  Emils Sietins, Luis Sagaon-Teyssier et al.•International Journal of Sexual…•2025

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• Barriers and Facilitators to Oral HIV Pre-exposure Prophylaxis Use in Australia

  Open Access•Tyson Arapali, Sarah Warzywoda et al.•AIDS and Behavior•2026

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• Perceived influence of alcohol consumption, substance use, and mental health on PrEP adherence and condom use among PrEP-prescribed gay, bisexual, and other men-who-have-sex-with-men

  Open Access•Paul A Shuper, Thepikaa Varatharajan et al.•BMC Public Health•2022

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• Utilisation of HIV pre-exposure prophylaxis and preferences of alternative long-acting modalities among men who have sex with men in Hong kong

  Open Access•Tsz Ho Kwan, Denise Pui Chung Chan et al.•BMC Public Health•2025

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• Analysis of potential barriers for PrEP non-users among PrEP-eligible MSM in Germany

  Open Access•Helena Waldorf, Ulrich Marcus et al.•BMC Public Health•2026

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• Increasing emergency department admissions for chemsex-related intoxications in Barcelona, Spain, among people living with HIV

  Open Access•Gabriel Vallecillo, Alejandra Losada et al.•BMC Public Health•2022

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• Is Chemsex a Displacement of the Aids Risk? From Epidemiological Data to a Psychoanalytical Approach

  Pierre Bonny, Mickaël Peoc’h et al.•Studies in Gender and Sexuality•2025

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• Amphetamine-Type Stimulant Use and Associated Factors Among Men Who have Sex with Men in Bangkok

  Open Access•Jakkrapatara Boonruang, Donn Colby et al.•AIDS and Behavior•2025

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• Perceptions and Practicalities Influencing Pre-exposure Prophylaxis Adherence Among Men Who Have Sex with Men in England

  Open Access•Dora Arnold-Forster, Robert Horne et al.•AIDS and Behavior•2022

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• Chemsex Practices in PrEP

  Open Access•Lorena de la Mora, Ainoa Ugarte et al.•AIDS and Behavior•2022

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• Psychological and Behavioural Within-participant Predictors of Adherence to Oral HIV Pre-Exposure Prophylaxis (PrEP)

  Open Access•Alison Taylor, Alison D Taylor et al.•AIDS and Behavior•2023

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• Trends in Methamphetamine Use Among Men Who Have Sex with Men in New York City, 2004–2017

  Open Access•Alexis V Rivera, Graham Harriman et al.•AIDS and Behavior•2020

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• Pre-exposure prophylaxis (PrEP) uptake and adherence experiences of gay and bisexual men who engage in chemsex

  Open Access•Scott Maxwell, M Shahmanesh et al.•International Journal of Drug…•2022

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• HIV-Related Stigma and Treatment Adherence Among Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Crystal Meth in the Metropolitan Area of Mexico City

  Open Access•Leonardo Jiménez-Rivagorza, Ricardo Orozco et al.•Archives of Sexual Behavior•2024

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• Prática de chemsex entre homens que fazem sexo com homens (HSH) durante período de isolamento social por Covid-19

  Open Access•Álvaro Francisco Lopes De Sousa, Artur Acelino Francisco Luz Nunes Queiroz et…•Cadernos de Saude Publica•2020

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• Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women

  Jared M Baeten, Deborah Donnell et al.•New England Journal of Medicine•2012

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• Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

  Open Access•Virginia A Fonner, Sarah L Dalglish et al.•AIDS•2016

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• Risk Perception, Sexual Behaviors, and PrEP Adherence Among Substance-Using Men Who Have Sex with Men

  Open Access•Erik D Storholm, Jonathan E Volk et al.•Prevention Science•2017

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• Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men

  Open Access•Robert M Grant, Peter L Anderson et al.•The Lancet Infectious Diseases•2014

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• Preexposure Prophylaxis for HIV Infection among African Women

  Lut Van Damme, Amy Corneli et al.•New England Journal of Medicine•2012

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• Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men

  Peter L Anderson, David V Glidden et al.•Science Translational Medicine•2012

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• HIV pre-exposure prophylaxis (PrEP)

  Open Access•Christoph D Spinner, Christoph Boesecke et al.•Infection•2016

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• Recreational drug use, polydrug use, and sexual behaviour in HIV-diagnosed men who have sex with men in the UK

  Open Access•Marina Daskalopoulou, Alec Rodger et al.•The Lancet HIV•2014

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• Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD)

  Open Access•Sheena McCormack, D Dunn et al.•The Lancet•2016

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• Chemsex and the city

  Open Access•Aseel Hegazi, Ming Lee et al.•International Journal of STD & AIDS•2017

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• Sexualised drug taking among men who have sex with men

  Open Access•Andrew Tomkins, Ryan George et al.•Perspectives in Public Health•2019

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• On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection

  Jean‐michel Molina, Jean-Michel Molina et al.•New England Journal of Medicine•2015

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• Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

  Jeanne Marrazzo, Jeanne M Marrazzo et al.•New England Journal of Medicine•2015

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• Illicit drug use in sexual settings (‘chemsex’) and HIV/STI transmission risk behaviour among gay men in South London

  Adam Bourne, David Reid et al.•Sexually Transmitted Infections•2015

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• Exploring strategies for PrEP adherence and dosing preferences in the context of sexualized recreational drug use among MSM

  Elizabeth F Closson, Jennifer A Mitty et al.•AIDS Care•2018

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• Self-reported Recent PrEP Dosing and Drug Detection in an Open Label PrEP Study

  Open Access•for the iPrEx Study Team, K Rivet Amico et al.•AIDS and Behavior•2016

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• Predictors of Daily Adherence to HIV Pre-exposure Prophylaxis in Gay/Bisexual Men in the PRELUDE Demonstration Project

  Open Access•Stefanie J Vaccher, Mark A Marzinke et al.•AIDS and Behavior•2018

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• Determining the Roles that Club Drugs, Marijuana, and Heavy Drinking Play in PrEP Medication Adherence Among Gay and Bisexual Men

  Open Access•Christian Grov, H Jonathon Rendina et al.•AIDS and Behavior•2018

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• Sexualised drug use among sexual minority young adults in the United States

  Open Access•Annie Ristuccia, Caleb LoSchiavo et al.•International Journal of Drug…•2018

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• Chemsex, risk behaviours and sexually transmitted infections among men who have sex with men in Dublin, Ireland

  Open Access•Ronan W Glynn, Niamh Byrne et al.•International Journal of Drug…•2018

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• Sexualised drug use in the United Kingdom (UK)

  Open Access•Claire Edmundson, Ellen Heinsbroek et al.•International Journal of Drug…•2018

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• The new MTV generation

  Open Access•Mohamed A Hammoud, Stefanie Vaccher et al.•International Journal of Drug…•2018

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• Social norms related to combining drugs and sex (“chemsex”) among gay men in South London

  Open Access•Alysha-Karima Ahmed, Alysha‐Karima Ahmed et al.•International Journal of Drug…•2016

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• Chemsex behaviours among men who have sex with men

  Open Access•Scott Maxwell, M Shahmanesh et al.•International Journal of Drug…•2019

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