Dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean

A systematic review

Dados Bibliográficos

ID14966254
AutoresLetícia L M Santos (Universidade Federal de Goiás), Érika Carvalho De Aquino (0000-0002-5659-0308, Public Health Department, Institute of Tropical Pathology and Public Health, Federal University of Goias, Goiânia, Brazil.), Suleimy Marinho Fernandes (Universidade Federal de Goiás), Yves Mauro F Ternes (Public Health Department, Institute of Tropical Pathology and Public Health, Federal University of Goias, Goiânia, Brazil.), Valéria C de R Feres (Universidade Federal de Goiás)
Ano2023
Volume47
Páginas1
Data de publicação2023-02-10
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoRevista Panamericana de Salud Pública (JOURNAL)
Identificadores do periódicoISSN: 1020-4989 • E-ISSN: 1680-5348
EditoraPan American Health Organization (PUBLISHER • US)
DOI10.26633/rpsp.2023.34
IdiomaEN
Citações recebidas1
Referências citadas46

Objectives. To characterize the distribution profile of dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean and to identify possible factors associated with the risk of dissemination and severity of these arboviruses. Methods. The protocol of this review was registered on the PROSPERO platform. Searches were carried out in the following databases: Virtual Health Library, MEDLINE/PubMed, and Embase. The search terms were: Zika virus, Zika virus infection, dengue, dengue virus, chikungunya virus, chikungunya fever, epidemiology, observational study, Latin America, and Caribbean region. Studies that addressed the distribution of these arboviruses and the risk factors associated with dengue, Zika virus disease, and chikungunya, published between January 2000 and August 2020 in English, Portuguese, and Spanish, were included. Results. Of 95 studies included, 70 identified risk factors, clinical manifestations, and outcomes for arbovirus infections and 25 described complications and/or deaths. The highest frequency of confirmed cases was for dengue. Brazil reported most cases of the three arboviruses in the period analyzed. Environmental and socioeconomic factors facilitated the proliferation and adaptation of vectors, and host-related factors were reported to aggravate dengue. Most deaths were due to chikungunya, Zika virus disease caused most neurological alterations, and dengue resulted in greater morbidity leading to more frequent hospitalization. Conclusions. The review provides a broad view of the three arboviruses and the intrinsic aspects of infections, and highlights the factors that influence the spread of these viruses in the populations studied