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Maternal HIV infection and other factors associated with growth outcomes of HIV-uninfected infants in Entebbe, Uganda

Dados Bibliográficos

ID15097372
AutoresLawrence Muhangi (Uganda Virus Research Institute, autor correspondente), Swaib A Lule (0000-0002-6271-2033, Uganda Virus Research Institute), Harriet Mpairwe (0000-0003-1199-4859, Uganda Virus Research Institute), Juliet Ndibazza (Uganda Virus Research Institute), Moses Kizza (Uganda Virus Research Institute), Margaret Nampijja (0000-0002-1200-6042, Uganda Virus Research Institute), Esther Nakazibwe (Uganda Virus Research Institute), Macklyn Kihembo (Uganda Virus Research Institute), Alison M Elliott (0009-0001-7720-9190, Uganda Virus Research Institute), Emily L Webb (0000-0002-4019-7456, London School of Hygiene & Tropical Medicine)
Ano2013
Volume16
Fascículo9
Páginas1548-1557
Data de publicação2013-09-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoPublic Health Nutrition (JOURNAL)
Identificadores do periódicoISSN: 1368-9800 • E-ISSN: 1475-2727
EditoraCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980013000499
PMID23507372
PMCIDPMC3733066
OpenAlexW2027136067
IdiomaEN
Citações recebidas6
Referências citadas26

Objective To assess the associations between maternal HIV infection and growth outcomes of HIV-exposed but uninfected infants and to identify other predictors for poor growth among this population. Design Within a trial of de-worming during pregnancy, the cohort of offspring was followed from birth. HIV status of the mothers and their children was investigated and growth data for children were obtained at age 1 year. Length-for-age, weight-for-age and weight-for-length Z -scores were calculated for each child; Z -scores Setting The study was conducted in Entebbe municipality and Katabi sub-county, Uganda. Subjects The sample consisted of 1502 children aged 1 year: HIV-unexposed ( n 1380) and HIV-exposed not infected ( n 122). Results Prevalence of stunting, underweight and wasting was 14·2 %, 8·0 % and 3·9 %, respectively. There was evidence for an association between maternal HIV infection and odds of being underweight (adjusted OR = 2·32; 95 % CI 1·32, 4·09; P = 0·006) but no evidence for an association with stunting or with wasting. Young maternal age, low maternal education, low birth weight, early weaning and experiencing a higher number of episodes of malaria during infancy were independent predictors for stunting and underweight. A higher number of living children in the family was associated with wasting. Conclusions Maternal HIV infection was associated with being underweight in HIV-exposed uninfected infants. The success of programmes for prevention of mother-to-child HIV transmission means that an increasing number of infants will be born to HIV-infected women without acquiring HIV. Therefore, viable nutritional interventions need to be identified for this population

Biology · Body mass index · Environmental health · Human immunodeficiency virus (HIV · Low birth weight · Offspring · Overweight · Population · Pregnancy · Underweight · Wasting · Weight for Age · Child Nutrition and Water Access · Demography · HIV/AIDS Research and Interventions · Medicine · Poverty, Education, and Child Welfare · Immunology · Internal Medicine · Pediatrics

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    Open Access•John König Walles, John Walles et al.•Global Health Action•2017

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Obras citantes distintas6
Citações por ano0,46
Intervalo de citações2013 - 2020 (8)
Velocidade de citaçãohistorical
Altamente citadoNão
Tipos de citaçãoNeutras: 6
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