Neurodevelopmental Trajectories of Preterm Infants of Italian Native-Born and Migrant Mothers and Role of Neonatal Feeding

Dados Bibliográficos

ID15469699
AutoresDino Gibertoni (0000-0002-1722-3724, University of Bologna), Alessandra Sansavini (0000-0002-1991-9864, University of Bologna, autor correspondente), Silvia Savini (IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola), Chiara Locatelli (0000-0002-6014-4378, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola), Gina Ancora (0000-0002-2570-2020, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola), Enrica Perrone (0000-0002-2332-5612, University of Bologna), Magda Ialonardi (University of Bologna), Paola Rucci (0000-0002-7704-0831, University of Bologna), Maria Pia Fantini (0000-0002-3257-6552, University of Bologna), Giacomo Faldella (0000-0002-3116-4329, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola), Luigi Corvaglia (0000-0002-8119-7743, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola)
Ano2020
Volume17
Fascículo12
Páginas4588-4588
Data de publicação2020-06-25
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoInternational Journal of Environmental Research and Public Health (JOURNAL)
Identificadores do periódicoISSN: 1661-7827 • E-ISSN: 1660-4601
EditoraMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17124588
PMID32630587
OpenAlexW3037128835
IdiomaEN
Citações recebidas2
Referências citadas33

There is evidence that preterm infants of migrant mothers are at a higher risk of adverse perinatal outcomes than those of native-born mothers, and that human milk feeding is beneficial to infants' neurodevelopment. Using the United Nations Human Development Index (HDI) to classify mother's country of origin, we investigated whether type of neonatal feeding (human milk vs. mixed milk vs. exclusive formula milk) affected preterm newborn neurodevelopment varying across different HDI categories (Italian native-born vs. high HDI migrant vs. low HDI migrant) up to 2 years of age. Neurodevelopment of 530 infants born in Italy at ≤32 weeks of gestational age and/or weighing <1500 g was measured at 3-, 6-, 9-, 12-, 18-, and 24-months corrected age (CA) using the revised Griffiths Mental Development Scale 0-2 years. The trajectories of the general developmental quotient and its five subscales were estimated using mixed models. At 24-months CA only preterm infants of low HDI migrant mothers and fed exclusive formula milk showed moderate neurodevelopment impairment, with lower developmental trajectories of eye-hand coordination, performance, and personal-social abilities. Migrant mothers from low HDI countries and their preterm infants should be targeted by specific programs supporting maternal environment, infant development, and human or mixed milk neonatal feeding. Future research should focus on a deeper understanding of the mechanisms through which type of feeding and mother migrant conditions interact in influencing preterm infants' neurodevelopment

Biology · Developmental psychology · Gestational age · Infant development · Mental development · Pregnancy · Breastfeeding Practices and Influences · Child Nutrition and Feeding Issues · Demography · Infant Development and Preterm Care · Medicine · Psychology · Pediatrics