Circulation of Respiratory Viruses in Hospitalized Adults before and during the Covid-19 Pandemic in Brescia, Italy

A Retrospective Study

Dados Bibliográficos

ID15499280
AutoresMaria Antonia De Francesco (0000-0003-2221-6286, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, autor correspondente), Caterina Pollara (Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia), Franco Gargiulo (Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia), Mauro Giacomelli (Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia), Arnaldo Caruso (0000-0001-5178-566X, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia)
Ano2021
Volume18
Fascículo18
Páginas9525-9525
Data de publicação2021-09-09
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoInternational Journal of Environmental Research and Public Health (JOURNAL)
Identificadores do periódicoISSN: 1661-7827 • E-ISSN: 1660-4601
EditoraMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18189525
PMID34574450
OpenAlexW3197574757
IdiomaEN
Citações recebidas4
Referências citadas6

Different preventive public health measures were adopted globally to limit the spread of SARS-CoV-2, such as hand hygiene and the use of masks, travel restrictions, social distance actions such as the closure of schools and workplaces, case and contact tracing, quarantine and lockdown. These measures, in particular physical distancing and the use of masks, might have contributed to containing the spread of other respiratory viruses that occurs principally by contact and droplet routes. The aim of this study was to evaluate the prevalence of different respiratory viruses (influenza viruses A and B, respiratory syncytial virus, parainfluenza viruses 1, 2, 3 and 4, rhinovirus, adenovirus, metapneumovirus and human coronaviruses) after one year of the pandemic. Furthermore, another aim was to evaluate the possible impact of these non-pharmaceutical measures on the circulation of seasonal respiratory viruses. This single center study was conducted between January 2017-February 2020 (pre-pandemic period) and March 2020-May 2021 (pandemic period). All adults >18 years with respiratory symptoms and tested for respiratory pathogens were included in the study. Nucleic acid detection of all respiratory viruses was performed by multiplex real time PCR. Our results show that the test positivity for influenza A and B, metapneumovirus, parainfluenza virus, respiratory syncytial virus and human coronaviruses decreased with statistical significance during the pandemic. Contrary to this, for adenovirus the decrease was not statistically significant. Conversely, a statistically significant increase was detected for rhinovirus. Coinfections between different respiratory viruses were observed during the pre-pandemic period, while the only coinfection detected during pandemic was between SARS-CoV-2 and rhinovirus. To understand how the preventive strategies against SARS-CoV-2 might alter the transmission dynamics and epidemic patterns of respiratory viruses is fundamental to guide future preventive recommendations

Coronavirus · Coronavirus disease 2019 (COVID-19 · Human metapneumovirus · Metapneumovirus · Middle East respiratory syndrome coronavirus · Pandemic · Respiratory system · Respiratory tract infections · Rhinovirus · Virus · Infection Control and Ventilation · Medicine · Respiratory viral infections research · Internal Medicine · Virology