Oncotype DX Test Receipt among Latina/Hispanic Women with Early Invasive Breast Cancer in New Jersey
A Registry-Based Study
Dados Bibliográficos
| ID | 15501633 |
|---|---|
| Autores | Nicholas Acuna (0000-0002-8347-8389, University of Southern California), Jesse J Plascak (0000-0002-4277-2987, The Ohio State University), Jennifer Tsui (0000-0002-5616-9636, University of Southern California), Alice Stroup (0000-0003-3341-4018, Rutgers, the State University of New Jersey), Antoinette M Stroup (Department of Biostatistics & Epidemiology, Rutgers School of Public Health, Piscataway, NJ 08854, USA), Adana A M Llanos (0000-0001-9954-9121, Rutgers, the State University of New Jersey, autor correspondente) |
| Ano | 2021 |
| Volume | 18 |
| Fascículo | 10 |
| Páginas | 5116-5116 |
| Data de publicação | 2021-05-12 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | International Journal of Environmental Research and Public Health (JOURNAL) |
| Identificadores do periódico | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Editora | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph18105116 |
| PMID | 34065945 |
| OpenAlex | W3160022731 |
| Idioma | EN |
| Referências citadas | 38 |
Oncotype DX ® (ODX) is a valid test of breast cancer (BC) recurrence risk and chemotherapy benefit. The purpose of this study was to examine prevalence of and factors associated with receipt of ODX testing among eligible Latinas/Hispanics diagnosed with BC. Sociodemographic and tumor data of BC cases diagnosed between 2008 and 2017 among Latina/Hispanic women ( n = 5777) were from the New Jersey State Cancer Registry (NJSCR). Eligibility for ODX testing were based on National Comprehensive Cancer Network guidelines. Multivariable logistic regression models of ODX receipt among eligible women were used to estimate adjusted odds ratios (AOR) and 95% confidence intervals (CI) by demographic and clinicopathologic factors. One-third of Latinas/Hispanics diagnosed with BC were eligible for ODX testing. Among the eligible, 60.9% received ODX testing. Older age (AOR 0.08, 95% CI: 0.04, 0.14), low area-level SES (AOR 0.58, 95% CI: 0.42, 0.52), and being uninsured (AOR 0.58, 95% CI: 0.39, 0.86) were associated with lower odds of ODX testing. While there was relatively high ODX testing among eligible Latina/Hispanic women with BC in New Jersey, our findings suggest that age, insurance status, and area-level SES contribute to unequal access to genetic testing in this group, which might impact BC outcomes
Breast cancer · Cancer · Cancer registry · Confidence interval · Logistic regression · Odds · Odds ratio · Receipt · BRCA gene mutations in cancer · Cancer Genomics and Diagnostics · Demography · Global Cancer Incidence and Screening · Medicine · Gerontology · Internal Medicine
| Velocidade de citação | historical |
|---|---|
| Altamente citado | Não |