Aberrant functional connectivity of the dorsolateral prefrontal cortex-nucleus accumbens during naturalistic stimulation in adolescent major depressive disorder

Dados Bibliográficos

ID15521950
AutoresYingzhe Zhao (Beijing Anding Hospital), Zhuo Xi (Harbin Medical University), Zhenxiang Zang (0000-0002-6865-054X), Z P ZANG (Beijing Anding Hospital), Zhi Yang (0000-0002-2341-5394, Beijing Anding Hospital), Jing Liu (0000-0002-0965-0320, Beijing Anding Hospital, autor correspondente)
Ano2026
Volume16
Páginas1705969-1705969
Data de publicação2026-01-05
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoFrontiers in Psychiatry (JOURNAL)
Identificadores do periódicoISSN: 1664-0640 • E-ISSN: 1664-0640
EditoraFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1705969
PMID41561996
OpenAlexW7118200853
IdiomaEN
Referências citadas37

These findings suggest that DLPFC-NAc hyperconnectivity is a neural substrate of MDD in adolescents and may preferentially contribute to anxiety-related or somatization-related symptomatology rather than depressive mood or sleep disturbance

Dorsolateral prefrontal cortex · Functional connectivity · Major depressive disorder · Mood · Mood disorders · Neural substrate · Nucleus accumbens · Prefrontal cortex · Schizophrenia (object-oriented programming · Functional Brain Connectivity Studies · Mental Health Research Topics · Transcranial Magnetic Stimulation Studies