Mobile App–Based Intervention for Adolescents With First-Episode Psychosis

Study Protocol for a Pilot Randomized Controlled Trial

Dados Bibliográficos

ID15522158
AutoresSara Barbeito (0000-0002-8454-3947, Universidad Internacional De La Rioja), Teresa Sánchez‐Gutiérrez (0000-0003-3124-4975, Universidad Internacional De La Rioja), Teresa Sánchez-Gutiérrez, María Mayoral (0000-0001-9272-5065, Centro de Investigación Biomédica en Red de Salud Mental), Miguel Moreno (0000-0002-9220-1015, Universidad Internacional De La Rioja), Sergio Ríos Aguilar (0000-0003-0225-6598, Universidad Internacional De La Rioja), Sergio Ríos-Aguilar, Celso Arango (0000-0003-3382-4754, Hospital General Universitario Gregorio Marañón), Ana Calvo (0000-0003-4372-5434, Universidad Internacional De La Rioja, autor correspondente)
Ano2019
Volume10
Páginas27-27
Data de publicação2019-02-05
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoFrontiers in Psychiatry (JOURNAL)
Identificadores do periódicoISSN: 1664-0640 • E-ISSN: 1664-0640
EditoraFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2019.00027
PMID30804818
OpenAlexW2914570318
IdiomaEN
Citações recebidas2
Referências citadas70

Introduction: Previous studies have shown an improvement in the access to treatment for patients with first-episode psychosis (FEP), specifically young patients, through mobile app-based interventions. The aim of this study is to test the effectiveness of a mobile app-based intervention to improve community functioning in adolescents with FEP. Mobile app-based interventions could increase quality of life and disease awareness, which improve adherence to treatment and reduce the frequency of relapses and rehospitalizations in adolescents with FEP. Methods: This article describes a mobile app treatment and the pilot trial protocol for patients with FEP. We will perform a single-blind randomized clinical trial (RCT) including patients with FEP aged 14-19 years recruited from Gregorio Marañón Hospital, Madrid, Spain. Patients will be randomly assigned to an intervention group, which will receive treatment as usual plus five modules of a psychological intervention through the mobile app (psychoeducation, recognition of symptoms and prevention of relapses, problem solving, mindfulness, and contact wall), or to a control group (standard care). The effectiveness of the intervention will be assessed by means of an extensive battery of clinical tests at baseline and at 3 months of follow-up. The primary outcome is reduction in psychotic and depressive symptoms; secondary outcomes comprise adherence, awareness, use of drugs, and quality of life. Data will be analyzed on an intention-to-treat (ITT) basis. Mixed model repeated-measures analysis will be used to explore the following effect: group × time interaction between the control group and the intervention group for clinical and functional variables during the follow-up period. Discussion: This is an innovative study for the assessment of a psychological intervention through a mobile app for patients with FEP during the critical period. This pilot RCT is intended to be a precursor to larger studies, which in turn could facilitate dissemination of mobile app therapy for patients with FEP. Ethics and Dissemination: The local ethics committee approved the study protocol. All participants must sign the informed consent, to participate. After finalizing the study, the results will be published. Trial registration: NCT03161249. NCT clinicaltrials.gov. Date of registration in primary registry 02 May 2017. clinicaltrials.gov

Clinical trial · Intervention (counseling · Mindfulness · Physical therapy · Psychiatry · Psychoeducation · Psychological intervention · Quality of life (healthcare · Randomized controlled trial · Bipolar Disorder and Treatment · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Medicine · Nursing · Schizophrenia research and treatment · Internal Medicine