Children With Autism Spectrum Disorder and Neurodevelopmental Regression Present a Severe Pattern After a Follow-Up at 24 Months
Dados Bibliográficos
| ID | 15526842 |
|---|---|
| Autores | Pilar Martín-Borreguero (Hospital Universitario Reina Sofía), Antonio Gómez-Fernández (Hospital Infanta Margarita), Antonio Rafael Gómez-Fernández, María José de la Torre‐Aguilar (0000-0002-2473-0660, Instituto Maimónides de Investigación Biomédica de Córdoba), Maria Jose De La Torre-Aguilar, Mercedes Gil‐Campos (0000-0002-9007-0242, Instituto Maimónides de Investigación Biomédica de Córdoba, autor correspondente), Katherine Flores‐Rojas (0000-0001-8692-0702, Instituto de Salud Carlos III), Katherine Flores-Rojas, Juan Luis Pérez-Navero (0000-0002-2026-5909, Instituto de Salud Carlos III) |
| Ano | 2021 |
| Volume | 12 |
| Páginas | 644324-644324 |
| Data de publicação | 2021-03-26 |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Frontiers in Psychiatry (JOURNAL) |
| Identificadores do periódico | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Editora | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2021.644324 |
| PMID | 33841211 |
| OpenAlex | W3143577379 |
| Idioma | EN |
| Citações recebidas | 1 |
| Referências citadas | 28 |
This study examined the presence of neurodevelopmental regression and its effects on the clinical manifestations and the severity of autism spectrum disorder (ASD) in a group of children with autism compared with those without neurodevelopmental regression at the time of initial classification and subsequently. Methods and Subjects: ASD patients were classified into two subgroups, neurodevelopmental regressive (AMR) and non-regressive (ANMR), using a questionnaire based on the Autism Diagnostic Interview-Revised test. The severity of ASD and neurodevelopment were assessed with the Childhood Autism Rating Scale Test-2, Strengths and Difficulties Questionnaire , and Pervasive Developmental Disorders Behavior Inventory Parent Ratings (PDDBI) and with the Battelle Developmental Inventory tests at the beginning of the study and after 24 months of follow-up. Fifty-two patients aged 2-6 years with ASD were included. Nineteen were classified with AMR, and 33 were classified with ANMR. Results: The AMR subgroup presented greater severity of autistic symptoms and higher autism scores. Additionally, they showed lower overall neurodevelopment. The AMR subgroup at 24 months had poorer scores on the Battelle Developmental Inventory test in the following areas: Total personal/social ( p p p p p p p p Conclusions: ASD patients exhibited a set of different neurological phenotypes. The AMR and ANMR subgroups presented different clinical manifestations and prognoses in terms of the severity of autistic symptoms and neurodevelopment
Autism · Autism spectrum disorder · Childhood Autism Rating Scale · Developmental psychology · Psychiatry · Rating scale · Autism Spectrum Disorder Research · Clinical Psychology · Family and Disability Support Research · Genetics and Neurodevelopmental Disorders · Medicine · Psychology · Pediatrics
| Citações por ano | 0,25 |
|---|---|
| Intervalo de citações | 2022 - 2022 (1) |
| Altamente citado | Não |