Mapping the structure of depression biomarker research

This study used bibliometric methods to characterize the body of literature and subject knowledge in the field of depression biomarker research. Among the core biomarkers of depression, functional magnetic resonance imaging (fMRI), cytokines, and oxidative stress are relatively well established; however, research on machine learning, metabolomics, and microRNAs holds potential for future development. We found "microRNAs" and "gut microbiota" to be the most recent burst terms in the study of depression biomarkers and the likely frontiers of future research

Bibliometrics · Biology · Biomarker · Data science · Depression (economics · Library science · Meta-analysis · Pathology · Web of science · Cancer-related cognitive impairment studies · Computer Science · Medicine · Psychology · Stress Responses and Cortisol · Tryptophan and brain disorders

• The role of inflammation in depression

  Open Access•Abraham H Miller, Andrew H Miller et al.•Nature Reviews Immunology•2016

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• Depression

  Open Access•Gin S Malhi, J John Mann•The Lancet•2018

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• Emerging trends and new developments in regenerative medicine

  Chaomei Chen, Rachael Dubin et al.•Expert Opinion on Biological…•2014

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• Inflammation and Its Discontents

  Open Access•Abraham H Miller, Andrew H Miller et al.•Biological Psychiatry•2009

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• Emerging trends in regenerative medicine

  Chaomei Chen, Zhigang Hu et al.•Expert Opinion on Biological…•2012

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• Major Depressive Disorder

  Robert H Belmaker, Galila Agam•New England Journal of Medicine•2008

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• Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

  Open Access•eQTLGen eQTLGen, Naomi R Wray et al.•Nature Genetics•2018

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• A few useful things to know about machine learning

  Open Access•Pedro Domingos•Communications of the ACM•2012

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• Peripheral cytokine and chemokine alterations in depression

  Open Access•Cristiano A Köhler, Thiago Holanda Freitas et al.•Acta Psychiatrica Scandinavica•2017

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• Childhood trauma and adulthood inflammation

  Open Access•D Baumeister, R Akhtar et al.•Molecular Psychiatry•2016

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• Resting-state connectivity biomarkers define neurophysiological subtypes of depression

  Open Access•Andrew T Drysdale, Logan Grosenick et al.•Nature Medicine•2017

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• Prevalence of mental disorders in China

  Open Access•Yueqin Huang, Yu Wang et al.•The Lancet Psychiatry•2019

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• Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the Covid-19 pandemic

  Open Access•Damian F Santomauro, Damian Santomauro et al.•The Lancet•2021

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• Bibliometric and Visual Analysis of Research on the Links Between the Gut Microbiota and Depression From 1999 to 2019

  Open Access•Xiuqing Zhu, Jinqing Hu et al.•Frontiers in Psychiatry•2021

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• A Bird's-Eye View of Exercise Intervention in Treating Depression Among Teenagers in the Last 20 Years

  Open Access•Yanwei You, Dizhi Wang et al.•Frontiers in Psychiatry•2021

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• Software survey

  Open Access•Nees Jan van Eck, Ludo Waltman•Scientometrics•2009

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