T Cell Deficits and Overexpression of Hepatocyte Growth Factor in Anti-inflammatory Circulating Monocytes of Middle-Aged Patients with Bipolar Disorder Characterized by a High Prevalence of the Metabolic Syndrome

T cell deficits most likely are a trait phenomenon of BD, since they have also been found in the other cohorts of BD patients and in bipolar offspring. Monocytes of this cohort showed an anti-inflammatory set point, suggesting that pro- and anti-inflammation are state characteristics of BD. The monocyte gene profile indicated an increased CAC activity; the question arises whether this is due to putative vessel damage in these relatively old patients with a high prevalence of the MetS

Biology · Bipolar disorder · Cohort · Hepatocyte growth factor · Immune system · Monocyte · Receptor · Diabetes and associated disorders · Electrolyte and hormonal disorders · Macrophage Migration Inhibitory Factor · Medicine · Endocrinology · Immunology · Internal Medicine

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