Carotid baroreflex sensitivity at rest and during psychological stress in offspring of hypertensives and non-twin sibling pairs

The baroreceptor reflexes of 38 young adult males were mechanically stimulated by negative external cervical pressure during a mental arithmetic task and pre-stress and post-stress relaxation periods. The subjects comprised 19 pairs of non-twin siblings. Baroreflex sensitivity was significantly less pronounced during arithmetic. Using non-invasive techniques, this finding replicates several others indicating a damping of the baroreceptor reflux during stress. More importantly, analyses of sibling similarities also revealed significant familiality of baroreflex sensitivity, independent of age, body mass, pressure applied and baseline heart rate. To examine the relationship between baroreflex sensitivity and parental history of hypertension, 21 young adult males with a parental history and 25 without participated in a second experiment. The two groups were not significantly different in resting baroreflex sensitivity. However, sensitivity was damped to a significantly greater degree during mental arithmetic in offspring of hypertensives, offering one possible explanation for their greater blood pressure reactivity to stress. These results suggest that familial influences may effect baroreflex sensitivity and, possibly as a result, blood pressure reactivity and risk for hypertension

Baroreceptor · Baroreflex · Biology · Blood pressure · Cardiology · Developmental psychology · Heart rate · Offspring · Pregnancy · Sibling · Heart Rate Variability and Autonomic Control · Internal Medicine · Medicine · Psychology

• Heart rate variability

  Open Access•Gary G Berntson, J Thomas Bigger et al.•Psychophysiology•1997

  Incluir item

• Stress and Heart Rate Variability

  Open Access•Hye-Geum Kim, Eun-Jin Cheon et al.•Psychiatry Investigation•2018

  Incluir item

• An Historical and Critical Review of the Articles on Blood Pressure Published in Psychosomatic Medicine Between 1939 and 1997

  Bernard T Engel•Psychosomatic Medicine•1998

  Incluir item

• Association of Elevated Blood Pressure With Low Distress and Good Quality of Life

  Angela Berendes, Thomas Meyer et al.•Psychosomatic Medicine•2013

  Incluir item