Adherence in people living with HIV/Aids, mental illness, and chemical dependency

Adherence to antiretroviral medications is central to reducing morbidity and mortality among people living with HIV/AIDS. Relatively few studies published to date address HIV adherence among special populations. The purpose of this article is to review the existing literature on HIV antiretroviral adherence, with an emphasis on studies among the triply diagnosed population of people living with HIV/AIDS, mental illness, and chemical dependency. In order to reflect the most current information available, data from conference proceedings, federally funded studies in progress, and the academic literature are presented for consideration

Antiretroviral therapy · Environmental health · Family medicine · Mental health · Mental illness · Population · Psychiatry · Viral load · HIV-related health complications and treatments · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Gerontology

• Substance Abuse and Psychiatric Disorders in HIV-Positive Patients

  Open Access•G Chander, Seth Himelhoch et al.•Drugs•2006

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• HIV and Depression – a systematic review of interventions

  Lorraine Sherr, Claudine Clucas et al.•Psychology, Health & Medicine•2011

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• A comparison of psychiatric diagnoses among HIV-infected prisoners receiving combination antiretroviral therapy and transitioning to the community

  Open Access•Angela Di Paola, Frederick L Altice et al.•Health & Justice•2014

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• Access for all – an analysis of children-related abstracts at the International Aids Conference, Bangkok

  Lorraine Sherr•Vulnerable Children and Youth…•2006

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• Treatment adherence following national antiretroviral rollout in South Africa

  Alta C van Dyk•African Journal of AIDS Research•2010

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• Latinos and HIV/Aids

  Open Access•Jeffrey S Gonzalez, Ellen Setsuko Hendriksen et al.•AIDS and Behavior•2008

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• Antiretroviral Drug Diversion Links Social Vulnerability to Poor Medication Adherence in Substance Abusing Populations

  Open Access•Kiyomi Tsuyuki, Hilary L Surratt•AIDS and Behavior•2015

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• Gender and Other Psychosocial Factors as Predictors of Adherence to Highly Active Antiretroviral Therapy (Haart) in Adults with Comorbid HIV/Aids, Psychiatric and Substance-related Disorder

  Open Access•Allison J Applebaum, Mark A Richardson et al.•AIDS and Behavior•2008

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• A global bibliometric analysis of antiretroviral treatment adherence

  Bach Xuan Tran, Chi Linh Hoang et al.•AIDS Care•2020

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• Adherence to antiretroviral medications and medical care in HIV-infected adults diagnosed with mental and substance abuse disorders

  Claude Ann Mellins, Jennifer Havens et al.•AIDS Care•2009

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• Psychiatric morbidity among HIV-infected children and adolescents in a resource-poor Kenyan urban community

  Judy W Kamau, Wangari Kuria et al.•AIDS Care•2012

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• Adherence to antiretroviral treatment among pregnant and postpartum HIV-infected women

  Claude Ann Mellins, C Chu et al.•AIDS Care•2008

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• Mental Disorder in People Living with HIV/Aids in South Africa

  Open Access•Melvyn Freeman, Nkululeko Nkomo et al.•South African Journal of Psychology•2008

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• Exploring the Interaction between Comorbid Psychiatric and Medical Diagnoses

  Open Access•Jonathan Nel, Jonathan Gordon Nel et al.•South African Journal of Psychology•2006

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• Adherence to combination antiretroviral therapies in HIV patients of low health literacy

  Seth C Kalichman, Bineetha Ramachandran et al.•Journal of General Internal…•1999

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• Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection

  Open Access•Joan S Tucker, M Audrey Burnam et al.•The American Journal of Medicine•2003

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• The Consistency of Adherence to Antiretroviral Therapy Predicts Biologic Outcomes for Human Immunodeficiency Virus–Infected Persons in Clinical Trials

  Sharon Mannheimer, Gerald Friedland et al.•Clinical Infectious Diseases•2002

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• Highly Active Antiretroviral Therapy in a Large Urban Clinic

  Open Access•Gregory M Lucas, Richard E Chaisson et al.•Annals of Internal Medicine•1999

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• Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

  Frank Joseph Palella, Kathleen M Delaney et al.•New England Journal of Medicine•1998

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• Impact of active drug use on antiretroviral therapy adherence and viral suppression in HIV-infected drug users

  Open Access•Julia H Arnsten, Penelope Demas et al.•Journal of General Internal…•2002

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• Sociodemographic and psychological variables influencing adherence to antiretroviral therapy

  Victoria Castro Gordillo, Victoria Gordillo et al.•AIDS•1999

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• Barriers to Use of Free Antiretroviral Therapy in Injection Drug Users

  Steffanie A Strathdee•JAMA•1998

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• Depressive and Anxiety Disorders in Women With HIV Infection

  Mary F Morrison, John M Petitto et al.•American Journal of Psychiatry•2002

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• Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease.

  Sheryl L Catz, Jeffrey A Kelly et al.•Health Psychology•2000

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• Impact of Adherence and Highly Active Antiretroviral Therapy on Survival in HIV-Infected Patients

  Patricia García De Olalla, Hernando Knobel et al.•JAIDS Journal of Acquired Immune…•2002

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• Trust and the Acceptance of and Adherence to Antiretroviral Therapy

  Frederick L Altice, Farzad Mostashari et al.•JAIDS Journal of Acquired Immune…•2001

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• Problem drinking and medication adherence among persons with HIV infection

  Robert L Cook, Susan M Sereika et al.•Journal of General Internal…•2001

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• Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population

  David R Bangsberg, FREDERICK HECHT et al.•AIDS•2000

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• Improved Survival Among HIV-Infected Individuals Following Initiation of Antiretroviral Therapy

  Robert S Hogg•JAMA•1998

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• Predictors of Self-Reported Adherence and Plasma HIV Concentrations in Patients on Multidrug Antiretroviral Regimens

  Allen L Gifford, Jill E Bormann et al.•JAIDS Journal of Acquired Immune…•2000

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• A prospective study of predictors of adherence to combination antiretroviral medication

  Carol E Golin, Honghu Liu et al.•Journal of General Internal…•2002

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• Antiretroviral Therapy Adherence and Viral Suppression in HIV‐Infected Drug Users

  Julia H Arnsten, Penelope Demas et al.•Clinical Infectious Diseases•2001

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• Relationship of gender, depression, and health care delivery with antiretroviral adherence in HIV-infected drug users

  Barbara J Turner, Christine Laine et al.•Journal of General Internal…•2003

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• Longitudinal assessment of the effects of drug and alcohol abuse on HIV-1 treatment outcomes in an urban clinic

  Gregory M Lucas, Kelly A Gebo et al.•AIDS•2002

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• Medication adherence among HIV+ adults

  Open Access•Charles H Hinkin, S A Castellon et al.•Neurology•2002

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• A Comparison Study of Multiple Measures of Adherence to HIV Protease Inhibitors

  Open Access•Honghu Liu, Carol E Golin et al.•Annals of Internal Medicine•2001

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• Mortality, CD4 Cell Count Decline, and Depressive Symptoms Among HIV-Seropositive Women

  Jeannette R Ickovics, Merle E Hamburger et al.•JAMA•2001

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• Correlates and Predictors of Adherence to Highly Active Antiretroviral Therapy

  Adriana Ammassari, Maria Paola Trotta et al.•JAIDS Journal of Acquired Immune…•2002

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• Adherence to Haart Regimens

  Margaret Chesney, Margaret A Chesney•AIDS Patient Care and STDs•2003

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• Patient adherence to treatment

  Open Access•Etienne Vermeire, Hilary Hearnshaw et al.•Journal of Clinical Pharmacy and…•2001

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• Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection

  Open Access•David L Paterson, Susan Swindells et al.•Annals of Internal Medicine•2000

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• Adherence to HIV Medications in a Cohort of Men Who Have Sex With Men

  Perry N Halkitis•Journal of Urban Health•2003

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• Posttraumatic stress disorder symptoms, salivary cortisol, medication adherence, and CD4 levels in HIV-positive individuals

  Douglas L Delahanty, Laura M Bogart et al.•AIDS Care•2004

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• Zidovudine adherence among individuals with HIV infection

  Richard D Muma, Michael W Ro et al.•AIDS Care•1995

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• Barriers to antiretroviral medication adherence in HIV-infected women

  Kathleen Johnston Roberts, Traci Mann•AIDS Care•2000

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• Self-reported adherence to antiretroviral medications among participants in HIV clinical trials

  Margaret A Chesney, Jeannette R Ickovics et al.•AIDS Care•2000

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• Correlates of adherence to combination antiretroviral therapy among members of HIV-positive mixed status couples

  Glenn J Wagner, Robert H Remien et al.•AIDS Care•2002

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• Adherence to Haart among patients with HIV

  Jeannette R Ickovics, Christina S Meade•AIDS Care•2002

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• Enhancing adherence to combination antiretroviral therapy in non-adherent HIV-positive men

  Shvawn McPherson-Baker, Robert M Malow et al.•AIDS Care•2000

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• Medication adherence strategies for drug abusers with HIV/Aids

  James L Sorensen, A Mascovich et al.•AIDS Care•1998

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• Determinants of compliance with antiretroviral therapy in patients with human immunodeficiency virus

  N Singh, Cheryl Squier et al.•AIDS Care•1996

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• The impact of psychiatric symptoms, drug use, and medication regimen on non-adherence to HIV treatment

  Karen Ingersoll•AIDS Care•2004

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• Progression to Aids

  Jane Leserman, Eric D Jackson et al.•Psychosomatic Medicine•1999

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• Use of Highly Active Antiretroviral Therapy in a Cohort of HIV-Seropositive Women

  Judith A Cook, Judith Α Cook et al.•American Journal of Public Health•2002

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• Antiretroviral Use and Pharmacy-Based Measurement of Adherence in Postpartum HIV-Infected Women

  Barbara J Turner, Craig J Newschaffer et al.•Medical Care•2000

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• Increasing drug users' adherence to HIV treatment

  Open Access•Robert S Broadhead, Douglas D Heckathorn et al.•Social Science & Medicine•2002

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• Adherence to HIV combination therapy

  Open Access•Margaret A Chesney, Michel Morin et al.•Social Science & Medicine•2000

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