Cytotoxic activity of selected Nigerian plants
Dados Bibliográficos
| ID | 20345708 |
|---|---|
| Autores | Abimbola Sowemimo (0000-0003-3140-4844, University of Lagos), Maryna Van de Venter (0000-0003-3816-1419, Nelson Mandela University, autor correspondente), Lucinda Baatjies (0000-0003-0669-9847, Nelson Mandela University), Trevor Koekemoer (0000-0002-8540-3276, Nelson Mandela University) |
| Ano | 2010 |
| Volume | 6 |
| Fascículo | 4 |
| Páginas | 526-8 |
| Data de publicação | 2010-07-29 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Identificadores do periódico | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Editora | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v6i4.57186 |
| PMID | 20606772 |
| OpenAlex | W1993276044 |
| Idioma | EN |
| Citações recebidas | 6 |
| Referências citadas | 3 |
Cancer is one of the most prominent human diseases which has stimulated scientific and commercial interest in the discovery of new anticancer agents from natural sources. The current study investigates the cytotoxic activity of ethanolic extracts of sixteen Nigerian plants used locally for the treatment of cancer using the MTT assay on the HeLa cell line. Sapium ellipticum leaves showed activity comparable to the reference compound Cisplatin and greater cytotoxic activity than Combretum paniculatum, Celosia trigyna, Drymaria cordata, Cyathula achyranthoides and Cyathula prostata. Justica extensa, Pupalia lappacea, Hedranthera barteri leaves, Alternanthera sessilis, Ethulia conyzoides leaves, Combretum zenkeri root, Sapium ellipticum stembark and Lannea nigritana stembark showed very low activity while Combretum molle, Adenanthera parvoniana and Lannea acida showed no activity. The results justify the use of Sapium, Combretum, Celosia, Drymaria and Cyathula in traditional treatment of cancer
Biology · Botany · Cancer · Cancer cell · Cancer cell lines · Cell · Combretaceae · Cytotoxic T cell · Cytotoxicity · HeLa · In vitro · Traditional medicine · Drug-Induced Hepatotoxicity and Protection · Ethnobotanical and Medicinal Plants Studies · Medicine · Natural Antidiabetic Agents Studies · Biochemistry
Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells
A review of the medicinal uses, phytochemistry and pharmacology of the genus Sapium
Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae)
Ethnopharmacological insights into native medicinal plants for cancer management by indigenous and local communities of Africa
Antiproliferative and apoptosis inducing activity of Markhamia tomentosa leaf extract on HeLa cells
Analgesic and Antipyretic Activities of Drymaria cordata (Linn.) Willd (Caryophyllaceae) Extract
| Obras citantes distintas | 6 |
|---|---|
| Citações por ano | 0,4 |
| Intervalo de citações | 2011 - 2026 (16) |
| Velocidade de citação | current |
| Altamente citado | Não |