Astragaloside III from Astragalus membranaceus antagonizes breast cancer growth
Dados Bibliográficos
| ID | 20345926 |
|---|---|
| Autores | S Wang (0000-0002-8677-1089), Steve Xinyao Wang (0009-0004-6328-081X, Central South University), L Tang (0000-0002-1013-1499, Central South University), F Chen (0000-0002-1244-2194, Central South University) |
| Ano | 2015 |
| Volume | 12 |
| Fascículo | 3 |
| Páginas | 183 |
| Data de publicação | 2015-07-30 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Identificadores do periódico | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Editora | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v12i3.23 |
| OpenAlex | W4254336797 |
| Idioma | EN |
| Referências citadas | 1 |
Background: Astragaloside III has been used to treat different cancers; however their effect on breast cancer remains unknown.Materials and methods: The present study examined the effects of Astragaloside III from Astragalus membranaceus on breast cancer cell lines in vitro as well as xenograft in vivo.Results: The results showed that the Astragaloside III could effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo. The potential mechanism is the induction of cell apoptosis signaling pathways.Conclusion: We believe that Astragaloside III provides a new therapeutic tool to treat breast cancer.Keywords: breast cancer; Astragaloside III; apoptosis; treatment
Apoptosis · Astragaloside · Astragalus · Biology · Breast cancer · Cancer · Cell growth · Human breast · In vitro · In vivo · MCF-7 · Pathology · Traditional Chinese medicine · Chemistry · Medicine · Metabolomics and Mass Spectrometry Studies · Traditional Chinese Medicine Analysis · Biochemistry · Cancer Research · Internal Medicine · Oncology · Pharmacology
| Velocidade de citação | historical |
|---|---|
| Altamente citado | Não |