Chronic Physiological Dysregulation and Changes in Depressive Symptoms
Testing Sex and Race as Vulnerability Factors
Dados Bibliográficos
| ID | 2073503 |
|---|---|
| Autores | Stacey N Doan (0000-0003-3661-2175, Claremont McKenna College, autor correspondente), Alexandra S Aringer (0009-0007-1017-9568, Claremont McKenna College), Jessica M Vicman (Claremont McKenna College), Thomas E Fuller-Rowell (0000-0002-1447-1175, Auburn University) |
| Ano | 2025 |
| Volume | 12 |
| Fascículo | 6 |
| Páginas | 3917-3924 |
| Data de publicação | 2025-12-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Journal of Racial and Ethnic Health Disparities (JOURNAL) |
| Identificadores do periódico | ISSN: 2196-8837 • E-ISSN: 2197-3792 |
| Editora | Springer Science and Business Media LLC (PUBLISHER) |
| DOI | 10.1007/s40615-024-02189-5 |
| PMID | 39388078 |
| OpenAlex | W4403296088 |
| Idioma | EN |
| Referências citadas | 55 |
Depression is a growing public health concern that affects approximately 5% of adults in their lifetime (WHO in Depression, 2021). Understanding the biological correlates of depression is imperative for advancing treatment. Of particular interest is allostatic load, a multisystem indicator of chronic physiological dysregulation (McEwen and Seeman in, Ann N Y Acad Sci, 1999). The current longitudinal study examined the association between allostatic load, depressive symptoms, and the moderating roles of sex and race. Participants consisted of 150 young adults (Mage = 18.81) who reported their demographics and depressive symptoms at T1 and T2, a year and a half later. Allostatic load was computed using indicators of metabolic, cardiovascular, and neuroendocrine functioning. Allostatic load was found to predict changes in depressive symptoms. Moreover, interaction effects models revealed that the associations between allostatic load and depressive symptoms at follow-up were further influenced by sex, such that the relationship was significant for males, with pronounced effects for Black males in particular. Black males may be particularly vulnerable to the mental health consequences of biological dysregulation
Anxiety · Biology · Depression (economics · Depressive symptoms · Pathology · Psychiatry · Public health · Quality of Life Research · Race (biology · Vulnerability (computing · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Medicine · Psychology · Resilience and Mental Health · Stress Responses and Cortisol · Epidemiology · Internal Medicine
Adolescent Onset of the Gender Difference in Lifetime Rates of Major Depression
Stress and the Individual
The weathering hypothesis as an explanation for racial disparities in health
Barriers to help-seeking by men
A Systematic Review of Allostatic Load, Health, and Health Disparities
The Epidemiology of Major Depressive Disorder
Convenience samples of college students and research reproducibility
The gender gap in suicide and premature death or
Racial and ethnic differences in depression
Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States
Gender differences in depression, anxiety, and stress among college students
Gender differences in depression
Mood disorders and allostatic load
Protective and Damaging Effects of Mediators of Stress
Childhood Poverty and Health
Causal Relationship Between Stressful Life Events and the Onset of Major Depression
Stress, Adaptation, and Disease
Allostatic Load, Income, and Race Among Black and White Men in the United States
Reaction Time in Adolescence, Cumulative Allostatic Load, and Symptoms of Anxiety and Depression in Adulthood
Exploration of Attitudes and Experiences of Young Adults Who Do and Do Not Attend College
Stress of stoicism
Sex differences in depressive symptom expression and help-seeking among college students
Weathering” and Age Patterns of Allostatic Load Scores Among Blacks and Whites in the United States
Perceived Discrimination Among African American Adolescents and Allostatic Load
Allostatic Load Among Non-Hispanic Whites, Non-Hispanic Blacks, and People of Mexican Origin
Cumulative biological risk and socio-economic differences in mortality
Gender differences in depression in representative national samples
Is there an independent association between burnout and increased allostatic load? Testing the contribution of psychological distress and depression
Depression and Physical Illness
Income Inequality, Gender Disparities, and Ethnic Differences
Stress Measured by Allostatic Load Score Varies by Reason for Immigration
| Velocidade de citação | historical |
|---|---|
| Altamente citado | Não |