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Internet‐Based Acceptance and Commitment Therapy With Interoceptive Exposure for Panic Disorder

A Randomized Controlled Trial and Working Alliance Analysis

Dados Bibliográficos

ID21391803
AutoresLisa Bäckman (0000-0001-8148-2547, Department of Psychology University of Gothenburg Gothenburg Sweden, autor correspondente), Sandra Weineland (0000-0003-2428-4004, Department of Psychology University of Gothenburg Gothenburg Sweden), Kristofer Vernmark (0000-0003-4250-8868, Department of Behavioural Sciences and Learning (IBL) Linköping University Linköping Sweden), Ella Radvogin (Psykologpartners Stockholm Stockholm Sweden), Pär Bjälkebring (0000-0002-4430-4044, Department of Psychology University of Gothenburg Gothenburg Sweden), Esther Enbuske (Department of Psychology University of Uppsala Uppsala Sweden), Ida Hermansson (0000-0002-9774-8503, Department of Psychology University of Uppsala Uppsala Sweden), Nina Johansson (0000-0002-3842-4832, Department of Psychology University of Uppsala Uppsala Sweden), Nathalie Petersen (Department of Psychology University of Uppsala Uppsala Sweden), Timo Hursti (0000-0003-1990-5785, Department of Psychology University of Uppsala Uppsala Sweden)
Ano2026
Volume67
Fascículo2
Páginas605-619
Data de publicação2026-04-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoScandinavian Journal of Psychology (JOURNAL)
Identificadores do periódicoISSN: 0036-5564 • E-ISSN: 1467-9450
EditoraWiley (PUBLISHER • GB)
DOI10.1111/sjop.70045
PMID41315783
OpenAlexW4416809052
IdiomaEN
Referências citadas60

This study's primary aim was to evaluate the efficacy of an internet‐based Acceptance and Commitment Therapy (IACT) program modified to include interoceptive exposure for treating panic disorder with or without concurrent agoraphobia. Its secondary aim was to examine whether therapist‐ and client‐rated working alliances were related to treatment outcomes. This randomized controlled trial included 79 participants, assigned to either a treatment group ( n = 40) or a waitlist control group ( n = 39) over 10 weeks. The study investigated the effects on panic disorder and quality of life, as well as the relationship between working alliances (rated by therapists and clients) and treatment outcomes. At post‐treatment, there was a significant between‐group treatment effect on panic disorder symptoms, with an observed effect size of d = 0.92. The model‐predicted effect size based on the multilevel model was d GMA‐raw = 0.86. Furthermore, 43% of participants no longer met the diagnostic criteria. Participants with concurrent agoraphobia exhibited higher initial panic symptom scores and were less likely to be diagnosis‐free post‐treatment. However, they still experienced significant and large treatment effects, with an observed effect size d = 1.22 and d GMA‐raw = 0,99. There was no significant between‐group difference in quality‐of‐life measurements. The therapist‐rated working alliance was associated with treatment outcome, but no significant relationship was found for the client‐rated alliance. Overall, the study suggests that interoceptive exposure‐modified IACT is an effective treatment for panic disorder and shows promise for patients with concurrent agoraphobia

Acceptance and commitment therapy · Agoraphobia · Alliance · Multilevel model · Panic · Panic disorder · Randomized controlled trial · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Mindfulness and Compassion Interventions · Psychosomatic Disorders and Their Treatments

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