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Private sector antimalarial sales a decade after “test and treat”

A cross-sectional study of drug shop clients in rural Uganda

Dados Bibliográficos

ID22070045
AutoresVictoria Shelus (0000-0001-7418-6002, University of North Carolina at Chapel Hill), Nobert Mumbere (Mbarara University of Science and Technology), Edgar Mulogo (0000-0003-3859-453X, Mbarara University of Science and Technology), Edgar M Mulogo, Clare Barrington (0000-0001-7802-4051, University of North Carolina at Chapel Hill), Emmanuel Baguma (Mbarara University of Science and Technology), Rabbison Muhindo (0000-0001-9651-6973, Mbarara University of Science and Technology), James E Herrington (University of North Carolina at Chapel Hill), Michael Emch (0000-0003-2642-965X, University of North Carolina at Chapel Hill), Suzanne Maman (0000-0003-4048-1585, University of North Carolina at Chapel Hill), Ross M Boyce (0000-0002-9489-6324, University of North Carolina at Chapel Hill, autor correspondente)
Ano2023
Volume11
Páginas1140405-1140405
Data de publicação2023-03-28
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoFrontiers in Public Health (JOURNAL)
Identificadores do periódicoISSN: 2296-2565 • E-ISSN: 2296-2565
EditoraFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1140405
PMID37056663
OpenAlexW4361214309
IdiomaEN
Citações recebidas2
Referências citadas40

Background: The World Health Organization has promoted "test and treat" guidelines for malaria since 2010, recommending all suspected malaria cases be confirmed with a parasitological test, typically a rapid diagnostic test (RDT), prior to treatment with antimalarial medications. However, many fevers at private drug shops in Uganda continue to be treated presumptively as malaria without diagnostic testing. Methods: = 46) recorded information about sales interactions with clients reporting fever or requesting antimalarials and collected capillary blood samples from clients who purchased medications without an RDT. We estimated the proportion of clients who purchased an RDT, adhered to the RDT result, and received antimalarials without having laboratory-confirmed malaria. Results: Most drug shops were unlicensed (96%) and sold RDTs (98%). Of 934 clients with suspected malaria who visited study drug shops during the data collection period, only 25% bought an RDT. Since some clients reported previous RDTs from the public sector, 40% of clients were aware of their malaria status at the drug shop. Among those with negative tests, 36% still purchased antimalarials. Sixty-five percent of clients who purchased an antimalarial without an RDT subsequently tested negative. Conclusions: Despite national guidelines, drug shop clients who purchase antimalarials from drug shops in Bugoye are often not tested to confirm a malaria diagnosis prior to treatment. Most clients treated presumptively with antimalarials did not have malaria. Interventions are needed to improve malaria case management and rational drug use in the private sector

Business · Cross-sectional study · Drug · Environmental health · Malaria · Malaria Research and Control · Medicine · Parasitic Diseases Research and Treatment · Pharmaceutical Quality and Counterfeiting · Pharmacology

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Obras citantes distintas2
Citações por ano1
Intervalo de citações2024 - 2025 (2)
Velocidade de citaçãorecent
Altamente citadoNão
Tipos de citaçãoNeutras: 2
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