Preferences, beliefs, and attitudes about oral fluid and blood-based HIV self-testing among truck drivers in Kenya choosing not to test for HIV

Dados Bibliográficos

ID22083813
AutoresJoanne E Mantell (0000-0002-0748-5974, New York Psychoanalytic Society and Institute, autor correspondente), Aleya Khalifa (0000-0001-8234-1295, ICAP Global Health), Stephanie N Christian (0000-0001-5678-8376, University of Pittsburgh), Matthew L Romo (0000-0002-3038-0644, City University of New York), Eva Mwai, Gavin George (0000-0001-7258-8470, Lund University), Michael Strauss (0000-0001-7849-8812, University of KwaZulu-Natal), Kaymarlin Govender (0000-0002-9586-1510, University of KwaZulu-Natal), Elizabeth A Kelvin (0000-0002-0566-8697, City University of New York)
Ano2022
Volume10
Páginas911932-911932
Data de publicação2022-11-09
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoFrontiers in Public Health (JOURNAL)
Identificadores do periódicoISSN: 2296-2565 • E-ISSN: 2296-2565
EditoraFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.911932
PMID36438254
OpenAlexW4308722330
IdiomaEN
Citações recebidas1
Referências citadas58

Introduction: Clinical trials in sub-Saharan Africa support that HIV self-testing (HIVST) can increase testing rates in difficult-to-reach populations. However, trials mostly evaluate oral fluid HIVST only. We describe preferences for oral fluid vs. blood-based HIVST to elucidate prior trial results and inform testing programs. Methods: Participants were recruited from a HIVST randomized controlled trial in Nakuru County, Kenya, which aimed to test the effect of choice between oral HIVST and facility-based testing compared to standard-of-care on HIV testing among truck drivers. We conducted in-depth interviews (IDIs) with purposively sampled trial participants who declined HIV testing at baseline or who were offered access to oral fluid HIVST and chose not to pick up the kit during follow-up. IDIs were conducted with all consenting participants. We first describe IDI participants compared to the other study participants, assessing the statistical significance of differences in characteristics between the two samples and then describe preferences, beliefs, and attitudes about HIVST biospecimen type expressed in the IDIs. Results: = 0.093). Of the 14 participants who answered the question about preferred type of HIVST, nine preferred blood-based HIVST, and five, oral HIVST. Preference varied by study arm with four of five participants who answered this question in the Choice arm and five of nine in the SOC arm preferring blood-based HIVST. Six key themes characterized truckers' views about test type: (1) Rapidity of return of test results. (2) Pain and fear associated with finger prick. (3) Ease of use. (4) Trust in test results; (5) fear of infection by contamination; and (6) Concerns about HIVST kit storage and disposal. Conclusion: We found no general pattern in the themes for preference for oral or blood-based HIVST, but if blood-based HIVST had been offered, some participants in the Choice arm might have chosen to self-test. Offering choices for HIVST could increase testing uptake

Clinical trial · Family medicine · Randomized controlled trial · Ethics in Clinical Research · HIV Research and Treatment · HIV/AIDS Research and Interventions · Medicine · Internal Medicine