Assessment of the financial toxicity in patients with differentiated thyroid cancer

A cross-sectional study in western China

Dados Bibliográficos

ID22089239
AutoresJun Zhou (0000-0003-1374-8248, Leshan Normal University), Zhou Jun (0000-0003-2423-0188), Chen Qiaoling (Qujiang People's Hospital), Qianqian Li (0000-0002-5462-3460, Leshan Normal University), Li Qianqian (0000-0003-0749-5811), Hua Jiang (0000-0001-9347-5782, University of Electronic Science and Technology of China), Jiang Hua (0000-0002-9801-1175), Lei Yu (0000-0001-7883-197X, Leshan Normal University), Xue Yang (0000-0001-9747-6467, Leshan Normal University), Yang Xue (0009-0006-9498-9420), Liu Lemei, Liu Le-mei (Leshan Normal University), Li Fanmin, LI Fan-min (Leshan Normal University, autor correspondente)
Ano2025
Volume13
Páginas1391744-1391744
Data de publicação2025-05-15
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoFrontiers in Public Health (JOURNAL)
Identificadores do periódicoISSN: 2296-2565 • E-ISSN: 2296-2565
EditoraFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1391744
PMID40443922
OpenAlexW4410416674
IdiomaEN
Citações recebidas1
Referências citadas44

Objective Using the Comprehensive Score for Financial Toxicity (COST) tool to measure financial toxicity (FT) among differentiated thyroid cancer (DTC) patients in China and investigate the association between FT and psychological distress. Methods We carried out a cross-sectional investigation of individuals who had survived DTC in two tertiary medical facilities. The assessment of FT was performed using the Chinese version of the COST tool. The National Comprehensive Cancer Network (NCCN) Distress Thermometer (DT) was used to measure psychological distress. A multivariate logistic regression model was constructed to identify factors related to FT, and the Pearson correlation was used to evaluate the association between COST and DT scores. Results Out of the 207 patients who participated in this study, the average COST score was 16.3. Notably, the prevalence of financial toxicity was 47.8% (95% CI: 41% ~ 54.7%) of the patients. Of these, 22.7% (47/207) were mild FT, 23.7% (49/207) were moderate FT, and 1.4% (3/207) were severe FT. Four variables were found to be associated with increased FT in the logistic regression model, younger age (odd ratio [OR], 4.52; p = 0.003), lower educational level [OR], 1.13; p = 0.040, uninsured (odd ratio [OR], 6.53; p = 0.028), had lower household income (odd ratio [OR], 6.34; p = 0.037), and advanced cancer (odd ratio [OR], 2.99; p = 0.034). Furthermore, the Pearson correlation revealed a mild correlation between financial toxicity and psychological distress (r = −0.53, p < 0.001). Conclusion In this study, the prevalence of FT in DTC patients was 47.8%. FT was associated with younger age, lower educational level, uninsured, had lower household income, and advanced cancer. Clinicians should identify patients by predictors early and conduct psychological interventions

Cancer · Cross-sectional study · Distress · Financial distress · Logistic regression · Pathology · Thyroid cancer · Toxicity · Clinical Psychology · Economic and Financial Impacts of Cancer · Health Systems, Economic Evaluations, Quality of Life · Healthcare Policy and Management · Medicine · Internal Medicine · Oncology