Why Stress Is Bad for Your Brain

Several recent studies of humans correlate stress with atrophy of the hippocampus, an area of the brain required for memory and cognition. In his Perspective, Sapolsky argues that the underlying causal agent may be glucocorticoids secreted in abnormally high amounts under stressful conditions.

Atrophy · Cognition · Cognitive psychology · Cognitive science · Hippocampus · Perspective (graphical) · Stress (linguistics) · Computer Science · Hormonal Regulation and Hypertension · Internal Medicine · Medicine · Neuroscience · Philosophy · Psychology · Stress Responses and Cortisol · Tryptophan and brain disorders

• The impact of group-based exposure therapy on the PTSD and depression of 30 combat veterans

  David J Ready, Patrick Sylvers et al.•Psychological Trauma Theory…•2011

  Incluir item

• Exceptions to the rule? Ethnographic alternatives to cumulative cultural evolution

  Open Access•George F Steiner•International Journal of Modern…•2020

  Incluir item

• Effects of Electroconvulsive Therapy and Repetitive Transcranial Magnetic Stimulation on Serum Brain-Derived Neurotrophic Factor Levels in Patients with Depression

  Open Access•Laura Gedge, Ashley Beaudoin et al.•Frontiers in Psychiatry•2012

  Incluir item

• Social and environmental stressors in the home and childhood asthma

  Shakira F Suglia, Cristiane S Duarte et al.•Journal of Epidemiology and…•2010

  Incluir item

• A hot/cool-system analysis of delay of gratification

  J Metcalfe, Walter Mischel•Psychological Review•1999

  Incluir item

• Maltreated children's memory

  Mitchell L Eisen, Gail S Goodman et al.•Developmental Psychology•2007

  Incluir item

• Religion, Families, and Health

  Duane F Alwin, John Bartkowski et al.•Religion, Families, and Health•2020

  Incluir item

• Gastrointestinal Diseases

  Open Access•Laurie Keefer, Tiffany H Taft et al.•Handbook of Psychology, Second…•2012

  Incluir item

• Increased Cortisol

  Open Access•Brandon J Auer•Encyclopedia of Evolutionary…•2017

  Incluir item

• Evolutionary Perspectives on Religion and Violence

  Open Access•Candace Alcorta, Candace S Alcorta et al.•Evolutionary Perspectives on…•2022

  Incluir item

• Child abuse

  Open Access•Donna Della Femina, Catherine A Yeager et al.•Child Abuse & Neglect•1990

  Incluir item

• Exercise

  Open Access•Carl W Cotman, C Cotman•Trends in Neurosciences•2002

  Incluir item

• The neurobiology of stress

  Open Access•Bruce S Mcewen•Brain Research•2000

  Incluir item

• A meta-analysis of heart rate variability and neuroimaging studies

  Open Access•Julian F Thayer, Fredrik Åhs et al.•Neuroscience & Biobehavioral…•2012

  Incluir item

• Stress and Heart Rate Variability

  Open Access•Hye-Geum Kim, Eun-Jin Cheon et al.•Psychiatry Investigation•2018

  Incluir item

• Central role of the brain in stress and adaptation

  Open Access•Bruce S Mcewen, Peter J Gianaros•Annals of the New York Academy of…•2010

  Incluir item

• The Mediational Role of Neurocognition in the Behavioral Outcomes of a Social-Emotional Prevention Program in Elementary School Students

  Open Access•Nathaniel R Riggs, Mark T Greenberg et al.•Prevention Science•2006

  Incluir item

• Executive function and the promotion of social–emotional competence

  Open Access•Nathaniel R Riggs, Laudan B Jahromi et al.•Journal of Applied Developmental…•2006

  Incluir item

• The Effects of Stress on Physical Activity and Exercise

  Open Access•Matthew A Stults-Kolehmainen, Matthew Stults‐kolehmainen et al.•Sports Medicine•2014

  Incluir item

• Building a Framework for Global Surveillance of the Public Health Implications of Adverse Childhood Experiences

  Open Access•Robert F Anda, A Butchart et al.•American Journal of Preventive…•2010

  Incluir item

• Biology and the Future of Psychoanalysis

  Eric R Kandel•American Journal of Psychiatry•1999

  Incluir item

• The enduring effects of abuse and related adverse experiences in childhood

  Open Access•Robert F Anda, Vincent J Felitti et al.•European Archives of Psychiatry…•2006

  Incluir item

• Protective and Damaging Effects of Stress Mediators

  Bruce S Mcewen, Jeffrey S Flier et al.•New England Journal of Medicine•1998

  Incluir item

• Stress, Adaptation, and Disease

  Open Access•Bruce S Mcewen•Annals of the New York Academy of…•1998

  Incluir item

• Job Strain and Trajectories of Cognitive Change Before and After Retirement

  Open Access•Corinne Nilsen, Monica Nelson et al.•The Journals of Gerontology…•2021

  Incluir item

• Effects of Group Practice of the Transcendental Meditation Program on Preventing Violent Crime in Washington, D.C

  Open Access•John S Hagelin, Maxwell Rainforth et al.•Social Indicators Research•1999

  Incluir item

• A Validity Study of the Positive Psychology Protective Profile

  Open Access•Linda W Morse, Kristine M Jacquin et al.•Psychological Reports•2003

  Incluir item

• Loneliness, Depression, and Genetics in the Elderly

  Open Access•María Luisa Delgado‐Losada, Jaime Bouhaben et al.•International Journal of…•2022

  Incluir item

• A Validity Study of the Positive Psychology Protective Profile

  Linda W Morse•Psychological Reports•2003

  Incluir item

• Current Posttraumatic Stress Symptoms Mediate the Relationship Between Adverse Childhood Experiences and Executive Functions

  Open Access•Rachel A Maja, Robyn E Kilshaw et al.•Psychological Reports•2021

  Incluir item

• Repeated Exposure to Conditioned Fear Stress Increases Anxiety and Delays Sleep Recovery Following Exposure to an Acute Traumatic Stressor

  Open Access•Benjamin N Greenwood, Rory Sascha Thompson et al.•Frontiers in Psychiatry•2014

  Incluir item

• Functional and Structural Alteration of Default Mode, Executive Control, and Salience Networks in Alcohol Use Disorder

  Open Access•Ji-Woo Suk, Soonjo Hwang et al.•Frontiers in Psychiatry•2021

  Incluir item

• Perceived Stress Predicts Subsequent Self-Reported Problems With Vision and Hearing

  Open Access•Markus Wettstein, Hans-Werner Wahl et al.•Research on Aging•2022

  Incluir item

• The place of play

  Patrick Jachyra, Caroline Fusco•Sport Education and Society•2014

  Incluir item

• Exploring the Intersection of Partner Stalking and Sexual Abuse

  Open Access•Tk Logan, T K Logan et al.•Violence Against Women•2011

  Incluir item

• Parents’ education as a determinant of educational childcare time

  Open Access•José Ignacio Giménez Nadal, J Ignacio Giménez-Nadal et al.•Journal of Population Economics•2012

  Incluir item

• Does professional development reduce the influence of teacher stress on teacher–child interactions in pre-kindergarten classrooms

  Open Access•Lia E Sandilos, Priscilla Goble et al.•Early Childhood Research Quarterly•2017

  Incluir item

• Problems Meeting Basic Needs Predict Cognitive Decline in Community-Dwelling Hispanic Older Adults

  Open Access•Natalie Sachs‐ericsson, Natalie Sachs-Ericsson et al.•Journal of Aging and Health•2009

  Incluir item

• Mindfulness Training in Childhood

  Philip David Zelazo, Kristen E Lyons•Human Development•2011

  Incluir item

• Integrating Neurological Findings with Transactional Analysis in Trauma Work

  Edward T Novak•Transactional Analysis Journal•2008

  Incluir item

• Socioeconomic status, gender and dementia

  Open Access•CAROLINE HASSELGREN, Lotta Dellve et al.•SSM - Population Health•2018

  Incluir item

• Hysterical Girls

  Marycatherine Mcdonald•International Journal of Feminist…•2018

  Incluir item

• Repressed anger mediates associations between sexual minority stressors and negative psychological outcomes in gay men and lesbian women

  Helen M Hendy, Lauren Joseph et al.•Journal of Gay & Lesbian Mental…•2016

  Incluir item

• Biology, Genes, and Resilience

  Open Access•Lucy Bowes, Sara R Jaffee•Trauma Violence & Abuse•2013

  Incluir item

• Contemporary work characteristics, stress, and ill health

  Open Access•Cheryl Sorenson Jamison, Michael Wallace et al.•American Journal of Human Biology•2004

  Incluir item

• Male lifespan and the secondary sex ratio

  Open Access•Ralph Catalano, T A Bruckner et al.•American Journal of Human Biology•2006

  Incluir item

• Minority stress, community involvement, and cognitive decline in rural SGM older adults

  Open Access•Harry Barbee, Tara Mckay•Social Science & Medicine•2026

  Incluir item

• Aggression and social support predict long‐term cortisol levels in captive tufted capuchin monkeys ( Cebus [Sapajus] apella )

  Open Access•Allie E Schrock, Corinne N Leard et al.•American Journal of Primatology•2019

  Incluir item

• Early Brain Growth Cessation in Wild Virunga Mountain Gorillas ( Gorilla beringei beringei )

  Open Access•Shannon C Mcfarlin, Sarah K Barks et al.•American Journal of Primatology•2013

  Incluir item

• Memory for traumatic experiences in early childhood

  Open Access•Ingrid M Cordón, Margaret-Ellen Pipe et al.•Developmental Review•2004

  Incluir item

• Marriage Protects Men from Clinically Meaningful Elevations in C-Reactive Protein

  David A Sbarra•Psychosomatic Medicine•2009

  Incluir item

• Cortisol Responses to Daily Events in Major Depressive Disorder

  Frenk Peeters, Nancy A Nicholson et al.•Psychosomatic Medicine•2003

  Incluir item

• Reaction Time in Adolescence, Cumulative Allostatic Load, and Symptoms of Anxiety and Depression in Adulthood

  Open Access•Catharine R Gale, George David Batty et al.•Psychosomatic Medicine•2015

  Incluir item

• Diseases Among Men 20 Years After Exposure to Severe Stress

  Joseph A Boscarino•Psychosomatic Medicine•1997

  Incluir item

• Midlife Psychological Distress Associated With Late-Life Brain Atrophy and White Matter Lesions

  Lena Johansson, INGMAR SKOOG et al.•Psychosomatic Medicine•2012

  Incluir item

• Depression-Like Behavior and Stressor-Induced Neuroendocrine Activation in Female Prairie Voles Exposed to Chronic Social Isolation

  Angela J Grippo, Bruce S Cushing et al.•Psychosomatic Medicine•2007

  Incluir item

• Implicit but Not Explicit Affectivity Predicts Circadian and Reactive Cortisol

  Open Access•Markus Quirin, Miguel Kazén et al.•Journal of Personality•2009

  Incluir item

• Bridging psychology and biology

  Stephen M Kosslyn, John T Cacioppo et al.•American Psychologist•2002

  Incluir item

• Dissociative Experience and Cultural Neuroscience

  Open Access•Rebecca Seligman, L J Kirmayer•Culture Medicine and Psychiatry•2008

  Incluir item

• Magical Flight and Monstrous Stress

  Open Access•J G Snodgra, Jeffrey G Snodgrass et al.•Culture Medicine and Psychiatry•2011

  Incluir item

• Health and Health Perceptions Among Kenyan Grandparents

  Open Access•Gillian H Ice, Amy Zidron et al.•Journal of Cross-Cultural…•2008

  Incluir item

• All Our Sons

  Open Access•Allan N Schore•Infant Mental Health Journal•2017

  Incluir item

• Who cares? Implications of care-giving and -receiving by HIV-infected or -affected older people on functional disability and emotional wellbeing

  Open Access•Makandwe Nyirenda, Maria Evandrou et al.•Ageing and Society•2015

  Incluir item

• Work environment predictors of beginning teacher burnout

  Open Access•Richard Goddard, Patrick O'Brien et al.•British Educational Research…•2006

  Incluir item

• Variation in hypothalamic–pituitary–adrenal axis activity among bullied and non‐bullied children

  Open Access•Tracy Vaillancourt, Eric Duku et al.•Aggressive Behavior•2008

  Incluir item

• Adapting to life’s slings and arrows

  Open Access•Christian E Waugh, Barbara L Fredrickson et al.•Journal of Research in Personality•2008

  Incluir item

• Challenge episodes over middle age

  Open Access•Ravenna Helson, Ravenna M Helson et al.•Journal of Research in Personality•2009

  Incluir item

• Perceived family and individual social status and its association with depression and suicidality in an adolescent clinical sample

  Open Access•Carol Vidal, Carl Latkin•Journal of Community Psychology•2020

  Incluir item

• Quantifying linear enamel hypoplasia in Virunga Mountain gorillas and other great apes

  Open Access•Kate Mcgrath, Sireen El‐zaatari et al.•American Journal of Physical…•2018

  Incluir item

• Stress associated with caregiving

  Open Access•Gillian H Ice, Aalyia Feroz Ali Sadruddin et al.•Social Science & Medicine•2012

  Incluir item

• Spirituality and Health

  Open Access•Carl E Thoresen•Journal of Health Psychology•1999

  Incluir item

• Age Differences in Exposure and Reactivity to Interpersonal Tensions among Black and White Individuals across Adulthood

  Open Access•Kira S Birditt, Kelly E Cichy et al.•Race and Social Problems•2011

  Incluir item