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Cocaine Use and HIV Infection in Intravenous Drug Users in San Francisco

Dados Bibliográficos

ID23363545
AutoresRichard E Chaisson (0000-0003-4710-925X, San Francisco General Hospital, autor correspondente)
Ano1989
Volume261
Fascículo4
Páginas561
Data de publicação1989-01-27
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoJAMA (JOURNAL)
Identificadores do periódicoISSN: 0098-7484 • E-ISSN: 1538-3598
EditoraAmerican Medical Association (AMA) (PUBLISHER)
DOI10.1001/jama.1989.03420040099027
PMID2909798
OpenAlexW2035142627
IdiomaEN
Citações recebidas86
Referências citadas1

We assessed risk factors for human immunodeficiency virus (HIV) infection in 633 heterosexual intravenous drug users. The HIV seroprevalence was 26% in blacks, 10% in Hispanics, and 6% in whites. Intravenous cocaine use significantly increased the risk of HIV infection, with a seroprevalence of 35% in daily cocaine users (odds ratio, 6.4; 95% confidence interval, 3.0 to 13.3). Black subjects were more likely to use cocaine regularly. Drug use in shooting galleries and sharing of drug injection equipment were also associated with HIV infection and were more common in cocaine users. By multivariate analysis, black race, daily cocaine injection by blacks and Hispanics, all other cocaine injection, heavy use prior to entry into methadone treatment by blacks, and use of drugs in shooting galleries were independent predictors of HIV infection. Methadone therapy was associated with substantial reductions in heroin use and some reduction in cocaine use, but 24% of cocaine users receiving methadone began or increased cocaine injection after entry into treatment.

Anesthesia · Antibody · Cocaine use · Condom · Confidence interval · Drug · Drug injection · Heroin · Human immunodeficiency virus (HIV) · Intravenous drug · Methadone · Methadone maintenance · Needle sharing · Odds ratio · Psychiatry · Seroprevalence · Substance abuse · Viral disease · HIV Research and Treatment · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine · Virology

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Obras citantes distintas86
Citações por ano2,32
Intervalo de citações1989 - 2021 (33)
Velocidade de citaçãohistorical
Altamente citadoNão
Tipos de citaçãoNeutras: 62
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