CYP2C19-mediated metabolic activation and OAT3/P-gp-associated transport contribute to Dioscorea bulbifera L.-induced hepatotoxicity
Dados Bibliográficos
| ID | 24020439 |
|---|---|
| Autores | Yuwei Tian (0000-0002-7715-9875, Guiyang Medical University), Liping Deng (0000-0001-7508-5289, Guiyang Medical University), Weiyu Guo (0000-0003-3021-8628, Guiyang Medical University), Zihao Cheng (Guiyang Medical University), Yongjun Li (0000-0001-6937-3540, Guiyang Medical University), Dingyan Lu (Guiyang Medical University, autor correspondente), Shiyu Zhang (0000-0001-5405-1645, Guiyang College of Traditional Chinese Medicine, autor correspondente), Jiang Zheng (0009-0000-6181-4110, Shenyang Pharmaceutical University, autor correspondente), Ting Liu (0000-0001-5479-7228, Guiyang Medical University, autor correspondente) |
| Ano | 2026 |
| Volume | 373 |
| Páginas | 122272-122272 |
| Data de publicação | 2026-08-05 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores do periódico | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editora | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2026.122272 |
| PMID | 42556633 |
| OpenAlex | W7172508717 |
| Idioma | EN |
| Referências citadas | 35 |
Efflux · Enzyme · Hepatocyte · In vivo · Intracellular · Liver injury · Metabolic pathway · Toxicity · Transporter · Chemotherapy-induced organ toxicity mitigation · Drug-Induced Hepatotoxicity and Protection · Potato Plant Research
| Velocidade de citação | historical |
|---|---|
| Altamente citado | Não |