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CYP2C19-mediated metabolic activation and OAT3/P-gp-associated transport contribute to Dioscorea bulbifera L.-induced hepatotoxicity

Dados Bibliográficos

ID24020439
AutoresYuwei Tian (0000-0002-7715-9875, Guiyang Medical University), Liping Deng (0000-0001-7508-5289, Guiyang Medical University), Weiyu Guo (0000-0003-3021-8628, Guiyang Medical University), Zihao Cheng (Guiyang Medical University), Yongjun Li (0000-0001-6937-3540, Guiyang Medical University), Dingyan Lu (Guiyang Medical University, autor correspondente), Shiyu Zhang (0000-0001-5405-1645, Guiyang College of Traditional Chinese Medicine, autor correspondente), Jiang Zheng (0009-0000-6181-4110, Shenyang Pharmaceutical University, autor correspondente), Ting Liu (0000-0001-5479-7228, Guiyang Medical University, autor correspondente)
Ano2026
Volume373
Páginas122272-122272
Data de publicação2026-08-05
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Ethnopharmacology (JOURNAL)
Identificadores do periódicoISSN: 0378-8741 • E-ISSN: 1872-7573
EditoraElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.122272
PMID42556633
OpenAlexW7172508717
IdiomaEN
Referências citadas35

Efflux · Enzyme · Hepatocyte · In vivo · Intracellular · Liver injury · Metabolic pathway · Toxicity · Transporter · Chemotherapy-induced organ toxicity mitigation · Drug-Induced Hepatotoxicity and Protection · Potato Plant Research

  • Anti-papillary thyroid carcinoma effects of dioscorea bulbifera L. through ferroptosis and the PI3K/AKT pathway based on network pharmacology and experimental validation

    Open Access•Yuzhi Gao, Zhendong Yang et al.•Journal of Ethnopharmacology•2024

Velocidade de citaçãohistorical
Altamente citadoNão
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