Disease exposure in infancy affects women's reproductive outcomes and offspring health in southern Sweden 1905-2000

Dados Bibliográficos

ID4599607
AutoresIngrid K Van Dijk (0000-0001-6549-9090, Lund University), Thomas Nilsson (0000-0002-9745-3449, Lund University), Therese Nilsson, Luciana Quaranta (0000-0003-3443-2568, Lund University, autor correspondente)
Ano2024
Volume347
Páginas116767
Data de publicação2024-04-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoSocial Science & Medicine (JOURNAL)
Identificadores do periódicoISSN: 0277-9536 • E-ISSN: 1873-5347
EditoraElsevier BV (PUBLISHER)
DOI10.1016/j.socscimed.2024.116767
PMID38518483
OpenAlexW4392698861
IdiomaEN
Citações recebidas2
Referências citadas57

Ample evidence demonstrates that early-life adversity negatively affects morbidity and survival in late life. We show that disease exposure in infancy also has a continuous impact on reproduction and health across the female life course and even affects early-life health of the next generation. Using Swedish administrative data, obstetric records, and local infant mortality rates as a measure of disease exposure, we follow women's reproductive careers and offspring health 1905-2000, examining a comprehensive set of outcomes. Women exposed to disease in infancy give birth to a lower proportion of boys, consistent with notions that male fetuses are more vulnerable to adverse conditions and are more often miscarried. Sons of exposed mothers are also more likely to be born preterm and have higher birthweight suggesting in utero out-selection. Exposed women have a greater risk of miscarriage and of male stillbirth, but their overall likelihood of giving birth is not affected

Biology · Disease · Environmental health · Fetus · In utero · Infant mortality · Live birth · Miscarriage · Offspring · Population · Pregnancy · Public health · Birth, Development, and Health · Demographic Trends and Gender Preferences · Demography · Health disparities and outcomes · Medicine · Gerontology