Bidirectional two-sample Mendelian randomization analysis identifies causal associations between relative carbohydrate intake and depression

Biology · Confidence interval · Gene · Genotype · Major depressive disorder · Mendelian randomization · Odds ratio · Relative risk · Diet and metabolism studies · Genetic Associations and Epidemiology · Medicine · Nutritional Studies and Diet · Psychology · Genetics · Internal Medicine · Physiology

• Quantifying the Behavioral Impact of Screen Exposure on Self-Regulation via Mendelian Randomization

  Open Access•Chun Miao, Peng Zhu et al.•IEEE Transactions on Computational…•2026

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• Risk of major depressive increases with increasing frequency of alcohol drinking

  Open Access•Weiyu Feng, Bing Zhang et al.•Frontiers in Public Health•2024

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• Women’s early reproductive behaviors and postpartum depression

  Open Access•Zhenyong Gao, Siyu Deng et al.•Critical Public Health•2025

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• Nutritional Epidemiology

  Walter C Willett, Walter Willett•Nutritional epidemiology•2012

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• Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

  Open Access•Jack Bowden, Gregory D Smith et al.•Genetic Epidemiology•2016

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• Plink

  Open Access•Shaun M Purcell, Shaun Purcell et al.•The American Journal of Human…•2007

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• Mediation Analysis

  Tyler J Vanderweele•Annual Review of Public Health•2016

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• Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

  Open Access•Marie Verbanck, Chia-Yen Chen et al.•Nature Genetics•2018

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• Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

  Open Access•Stephen Burgess, Adam S Butterworth et al.•Genetic Epidemiology•2013

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• Mendelian randomization

  Open Access•Deborah A Lawlor, Debbie A Lawlor et al.•Statistics in Medicine•2008

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• Mortality in Mental Disorders and Global Disease Burden Implications

  Elizabeth Reisinger Walker, Robin E Mcgee et al.•JAMA Psychiatry•2015

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• Mendelian randomization with invalid instruments

  Open Access•Jack Bowden, Gregory D Smith et al.•International Journal of…•2015

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• Risk Factors for Depression

  Constance Hammen•Annual Review of Clinical…•2018

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• Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

  Open Access•eQTLGen eQTLGen, Naomi R Wray et al.•Nature Genetics•2018

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• Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States

  Deborah S Hasin, Aaron L Sarvet et al.•JAMA Psychiatry•2018

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• Reading Mendelian randomisation studies

  Open Access•Neil M Davies, Michael V Holmes et al.•BMJ•2018

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• Identification of Causal Effects Using Instrumental Variables

  Joshua D Angrist, Guido W Imbens et al.•Journal of the American…•1996

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• Associations Between Smoking, Alcohol Consumption, Physical Activity and Depression in Middle-Aged Premenopausal and Postmenopausal Women

  Open Access•Hyewon Kim, Juhwan Yoo et al.•Frontiers in Psychiatry•2021

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• Causal associations between body mass index and mental health

  Nina van den Broek, Jorien L Treur et al.•Journal of Epidemiology and…•2018

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• Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits

  Open Access•J Merino, Hassan S Dashti et al.•Nature Human Behaviour•2021

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