Theta phase precession supports memory formation and retrieval of naturalistic experience in humans
Dados Bibliográficos
| ID | 4656219 |
|---|---|
| Autores | Jie Zheng (0009-0002-7853-6721, Cedars-Sinai Medical Center), Mar Yebra (0000-0001-8445-1893, Cedars-Sinai Medical Center), Andrea Gómez Palacio Schjetnan (0000-0002-4319-7689, University Health Network), Kramay Patel (0000-0002-5174-2309, University of Toronto), Chaim N Katz (0000-0001-7883-6412, University of Toronto), Michael Kyzar (0009-0004-4392-9933, Cedars-Sinai Medical Center), Clayton P Mosher (0000-0002-9213-3059, Cedars-Sinai Medical Center), Suneil K Kalia (0000-0003-2054-1915, University Health Network), Jeffrey M Chung (Cedars-Sinai Medical Center), C M Reed (0000-0002-7157-3645, Cedars-Sinai Medical Center), Taufik A Valiante (0000-0002-3443-3790, University Health Network), Adam N Mamelak (0000-0002-4245-6431, Cedars-Sinai Medical Center), Gabriel Kreiman (0000-0003-3505-8475, Boston Children's Hospital, autor correspondente), Ueli Rutishauser (0000-0002-9207-7069, California Institute of Technology, autor correspondente) |
| Ano | 2024 |
| Volume | 8 |
| Fascículo | 12 |
| Páginas | 2423-2436 |
| Data de publicação | 2024-10-03 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | Nature Human Behaviour (JOURNAL) |
| Identificadores do periódico | ISSN: 2397-3374 • E-ISSN: 2397-3374 |
| Editora | Springer Science and Business Media LLC (PUBLISHER) |
| DOI | 10.1038/s41562-024-01983-9 |
| PMID | 39363119 |
| OpenAlex | W4403104748 |
| Idioma | EN |
| Citações recebidas | 1 |
| Referências citadas | 70 |
Associating different aspects of experience with discrete events is critical for human memory. A potential mechanism for linking memory components is phase precession, during which neurons fire progressively earlier in time relative to theta oscillations. However, no direct link between phase precession and memory has been established. Here we recorded single-neuron activity and local field potentials in the human medial temporal lobe while participants (n = 22) encoded and retrieved memories of movie clips. Bouts of theta and phase precession occurred following cognitive boundaries during movie watching and following stimulus onsets during memory retrieval. Phase precession was dynamic, with different neurons exhibiting precession in different task periods. Phase precession strength provided information about memory encoding and retrieval success that was complementary with firing rates. These data provide direct neural evidence for a functional role of phase precession in human episodic memory
Cognitive psychology · Cognitive science · Epistemology · Naturalism · Computer Science · Memory and Neural Mechanisms · Neural dynamics and brain function · Neuroscience · Philosophy · Psychology · Sleep and Wakefulness Research
| Obras citantes distintas | 1 |
|---|---|
| Citações por ano | 1 |
| Intervalo de citações | 2025 - 2025 (1) |
| Velocidade de citação | recent |
| Altamente citado | Não |
| Tipos de citação | Neutras: 1 |