Effect of a One-Week Spiritual Retreat on Brain Functional Connectivity

Background: Many individuals participate in spiritual retreats to enhance their sense of spirituality or to improve their overall mental and spiritual well-being. We are not aware of any studies specifically evaluating changes in functional connectivity using functional magnetic resonance imaging (fMRI) in individuals undergoing an intense spiritual retreat program. The goal of this study was to determine whether such changes occur as a result of participating in the Spiritual Exercises of St. Ignatius. Methods: We conducted psychological and spiritual measures in conjunction with functional connectivity analysis of fMRI in 14 individuals prior to and following shortly after their participation in a one-week spiritual retreat. Results: Significant changes in functional connectivity were observed after the retreat program, compared to baseline evaluation, particularly in the posterior cingulate cortex, pallidum, superior frontal lobe, superior parietal lobe, superior and inferior temporal lobe, and the cerebellum. Significant changes in a variety of psychological and spiritual measures were identified as result of participation in the retreat. Conclusion: Overall, these preliminary findings suggest that this intensive spiritual retreat resulted in significant changes in brain functional connectivity, and warrants further investigation to evaluate the physiological, psychological, and spiritual impact of these changes

Anterior cingulate cortex · Cognition · Frontal lobe · Functional connectivity · Functional magnetic resonance imaging · Posterior cingulate · Spirituality · Temporal lobe · Grief, Bereavement, and Mental Health · Medicine · Neuroscience · Paranormal Experiences and Beliefs · Psychology · Religion, Spirituality, and Psychology

• The Spiritual Path of Transformation 1

  Open Access•Eckhard Frick•Journal of Analytical Psychology•2025

  Incluir item

• Philosophical Practice as Spiritual Exercises towards Truth, Wisdom, and Virtue

  Open Access•Xiaojun Ding, Fang Yu et al.•Religions•2022

  Incluir item

• Integrating clients’ religion and spirituality within psychotherapy

  Open Access•Laura E Captari, Joshua N Hook et al.•Journal of Clinical Psychology•2018

  Incluir item

• Religious involvement and mortality

  Michael E Mccullough, William T Hoyt et al.•Health Psychology•2000

  Incluir item

• A randomized controlled trial of mindfulness meditation versus relaxation training

  Shamini Jain, Shauna L Shapiro et al.•Annals of Behavioral Medicine•2007

  Incluir item

• Meditation experience is associated with differences in default mode network activity and connectivity

  Open Access•Judson A Brewer, Patrick D Worhunsky et al.•Proceedings of the National…•2011

  Incluir item

• Screening Depressed Patients in Family Practice

  Aaron T Beck, Roy W Beck•Postgraduate Medicine•1972

  Incluir item

• A 12-Item Short-Form Health Survey

  John E Ware, Mark Kosinski et al.•Medical Care•1996

  Incluir item

• Effect of a one-week spiritual retreat on dopamine and serotonin transporter binding

  Andrew B Newberg, Nancy Wintering et al.•Religion Brain & Behavior•2018

  Incluir item

• The 'world of yoga

  Open Access•Anne-Cécile Hoyez•Social Science & Medicine•2007

  Incluir item

• Religiousness and depression

  Tony Bagnall Smith, Timothy B Smith et al.•Psychological Bulletin•2003

  Incluir item