Inheritance of dermatoglyphic diversity in 500 Indian pedigrees

Complex segregation analysis

Dados Bibliográficos

ID5136246
AutoresBibha Karmakar (Indian Statistical Institute), Ika Malkin, E Kobyliansky (0000-0001-9691-3813)
Ano2009
Volume67
Fascículo3
Páginas237-251
Data de publicação2009-09-01
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoAnthropologischer Anzeiger (JOURNAL)
Identificadores do periódicoISSN: 0003-5548 • E-ISSN: 2363-7099
EditoraS ch we iz er ba rt (PUBLISHER)
DOI10.1127/0003-5548/2009/0023
PMID20405698
OpenAlexW2167936458
IdiomaEN
Citações recebidas2
Referências citadas19

The main goal of the present communication is to determine the mode of inheritance of dermatoglyphic diversity traits through complex segregation analyses (genetic model fittings). The data consists of a large ethnically homogeneous sample of 500 Indian pedigrees (2435 individuals) of two generations. Principal component analysis, familial correlations and segregation analysis (package MAN-5) were used. A little genetic effect obtained from familial correlations but no evidence of major gene contribution found to be involved. By segregation analysis of the traits- PC 1_ Div, Div 9 and Div 11, both Mendelian and Environmental models were rejected (<<0.001) with the General model, i.e. despite the presence of significant inheritance (rejection of Environmental model), the nature of inheritance is more complex, than Mendelian model.

Biology · Diversity (politics) · Evolutionary biology · Gene · Genealogy · Homogeneous · Inbreeding · Inheritance (genetic algorithm) · Major gene · Mendelian inheritance · Multifactorial Inheritance · Pedigree chart · Population · Principal component analysis · Single-nucleotide polymorphism · Sociology · Statistics · Demography · Dermatoglyphics and Human Traits · Genetics · History · Mathematics · Medical and Biological Sciences