Prevalence and risk factors for latent tuberculosis infection among primary health care workers in Brazil

Dados Bibliográficos

ID5167637
AutoresThiago Nascimento Do Prado (0000-0001-8132-6288, Universidade Federal do Espírito Santo), Lee W Riley (0000-0001-9916-3894, University of California, USA), Mauro Niskier Sanchez (0000-0002-0472-1804, Universidade de Brasília), Mauro Sanchez (Universidade de Brasília), Geisa Fregona (0000-0001-5835-8222, Universidade Federal do Espírito Santo), Renata Lyrio Peres Nóbrega (Universidade Federal do Espírito Santo), Lia Gonçalves Possuelo (0000-0002-6425-3678, Universidade de Santa Cruz do Sul), Eliana Zandonade (0000-0001-5160-3280, Universidade Federal do Espírito Santo), Rodrigo Leite Locatelli (Universidade Federal do Espírito Santo), Fernanda Mattos De Souza (0000-0003-2093-8816, Universidade Federal do Espírito Santo), Jayant V Rajan (University of California, USA), Ethel Leonor Noia Maciel (0000-0003-4826-3355, Universidade Federal do Espírito Santo)
Ano2017
Volume33
Fascículo12
Páginase00154916-e00154916
Data de publicação2017-12-18
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoCadernos de Saude Publica (JOURNAL)
Identificadores do periódicoISSN: 0102-311X • E-ISSN: 1678-4464
EditoraFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/0102-311x00154916
PMID29267691
OpenAlexW2772530644
SCIELO_PIDS0102-311X2017001205008
IdiomaEN
Citações recebidas2
Referências citadas29

Health care workers (HCW) are at increased risk of latent tuberculosis infection (LTBI) from occupational exposure to Mycobacterium tuberculosis. The objective was to determine the prevalence of and risk factors for LTBI among primary HCW in five Brazilian cities. We conducted a cross-sectional study, from 2011 to 2013, among primary HCW, using a structured questionnaire and an evaluated for LTBI using the Quantiferon-TB Gold in-tube test. The magnitude of the associations was assessed using hierarchical logistic regression models. Among 708 HCW, the LTBI prevalence was 27% (n = 196; 95%CI: 24%-31%). We found that the following factors were positively associated with LTBI in primary HCW: age > 50 years (OR = 2.94; 95%CI: 1.44-5.99), absence of a BCG scar (OR = 2.10; 95%CI: 1.28-3.43), self-reported ex-smoker status (OR = 1.80; 95%CI: 1.04-3.11), being a nurse (OR = 2.97; 95%CI: 1.13-7.83), being a nurse technician (OR = 3.10; 95%CI: 1.26-7.60), being a community health agent (OR = 2.60; 95%CI: 1.06-6.40), and irregular use of N95 masks (OR = 2.51; 95%CI: 1.11-5.98). In contrast, HCWs who do not work in health care facilities with a TB control program were less likely to have LTBI (OR = 0.66; 95%CI: 0.45-0.97). This study demonstrated a substantial occupational risk of LTBI among primary HCW in Brazil. The Brazilian TB control program, as well as local programs, need to target these high-risk HCW with education, as well as with better personal protective equipment to prevent acquisition of new TB infection

Cross-sectional study · Environmental health · Latent tuberculosis · Logistic regression · Mycobacterium tuberculosis · Pathology · Tuberculosis · Internal Medicine · Medicine · Pneumocystis jirovecii pneumonia detection and treatment · Pneumonia and Respiratory Infections · Tuberculosis Research and Epidemiology