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Isolation and Identification of Potential Antibiotic Producing Rare Actinomycetes from Rhizospheric Soils

Dados Bibliográficos

ID5222210
AutoresMobolaji Felicia Adegboye (North-West University), Olubukola Oluranti Babalola (0000-0003-4344-1909, North-West University)
Ano2016
Volume56
Fascículo1-2
Páginas31-41
Data de publicação2016-11-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Human Ecology (JOURNAL)
Identificadores do periódicoISSN: 0970-9274 • E-ISSN: 2456-6608
EditoraKamla Raj Enterprises (PUBLISHER)
DOI10.1080/09709274.2016.11907035
OpenAlexW2769847198
IdiomaEN
Referências citadas5

The search for novel antibiotics producers and their characterization continues to be an important objective in the discovery of novel bioactive compounds. This work was carried out to isolate and identify bioactive secondary metabolite producing rare actinomycetes and to analyse the phylogenetic relationship. The rhizospheric soil samples were collected from different localities of Ngaka Modiri Molema district of North West Province, South Africa and screened for antibacterial potential. Molecular identification of the bacterial isolates by analysis of the 16S rDNA nucleotides sequences showed that the isolates were as follows: Actinomadura, Nocardiopsis, Promicromonospora, Nocardia, Arthrobacter, Pseudonocardia, Micrococcus, Nonomuraea, Rhodococcus, Streptosporangiumand Saccharothrixspp. Nineteen (21.6%) of the 88 isolates exhibited antibacterial activity against at least one of the test organisms. Phylogenetic analysis revealed that the bacterial isolates are the members of rare actinomycetes which are associated with the rhizosphere. Results from the phylogenetic analysis indicate that the 19 isolates could be sorted into 11 phylotypes. It was also inferred from the tree that the potent bacterial isolates clustered with other antibiotic producing rare actinomycetes reference strains retrieved from the GenBank. This study corroborates that rhizospheric soil harbours diverse actinomycetes which can be explored for antibacterial secondary metabolites

16S ribosomal RNA · Actinomyces · Arthrobacter · Bacteria · Biology · Botany · GenBank · Microbacterium · Micromonospora · Nocardia · Phylogenetic tree · Rhizosphere · Streptomyces · Genetics, Bioinformatics, and Biomedical Research · Genomics and Phylogenetic Studies · Microbial Natural Products and Biosynthesis · Genetics · Microbiology

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Velocidade de citaçãohistorical
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