Parental Alcohol Use Predicts Neural Emotion Reactivity and Substance Use Intentions in Early Adolescence

Parents’ alcohol use may influence adolescent substance use and substance use intentions. Prior research has linked adolescents’ emotion reactivity with parental drinking behaviors and adolescent substance use. The present study investigated whether sub-clinical maternal alcohol use relates to adolescent neural emotion reactivity and substance use intentions in early adolescence. Early adolescents ( N = 70) viewed emotional images during a fMRI scan and completed a questionnaire about substance use intentions. Their mothers reported past 30-day alcohol use. Results showed that greater frequency of maternal alcohol use predicted adolescents’ substance use intentions. In addition, maternal alcohol use predicted adolescent blunted responses to positive emotional images in the ventromedial prefrontal cortex (vmPFC) and bilateral anterior cingulate cortex (ACC). There was no relationship between neural emotion reactivity and adolescent substance use intentions. Findings suggest that parental alcohol use may relate to adolescent’s development of reward and positive emotion processing systems, even at sub-clinical levels of drinking

Addiction · Alcohol · Cognition · Craving · Cue reactivity · Developmental psychology · Neural correlates of consciousness · Psychiatry · Reactivity (psychology · Substance use · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Chemistry · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Medicine · Psychology · Stress Responses and Cortisol

• The development of emotion regulation

  Open Access•Kateri Mcrae, James J Gro et al.•Social Cognitive and Affective…•2012

  Incluir item

• Modifiable parenting factors associated with adolescent alcohol misuse

  Open Access•Marie B H Yap, Tony W K Cheong et al.•Addiction•2017

  Incluir item

• Chronic Stress, Drug Use, and Vulnerability to Addiction

  Open Access•Rajita Sinha•Annals of the New York Academy of…•2008

  Incluir item

• Monitoring the Future national survey results on drug use, 1975-2017

  L D Johnston, Richard A Miech et al.•2018

  Incluir item

• Monitoring the Future national survey results on drug use, 1975-2018

  Lloyd D Johnston, Lloyd Johnston et al.•2019

  Incluir item

• Functional imaging studies of emotion regulation

  Open Access•Kevin N Ochsner, Martin Harwit et al.•Annals of the New York Academy of…•2012

  Incluir item

• Relation of parental alcoholism to early adolescent substance use

  Laurie Chassin, David R Pillow et al.•Journal of Abnormal Psychology•1993

  Incluir item

• Trends in Adult Alcohol Use and Binge Drinking in the Early 21st‐Century United States

  Open Access•Richard A Grucza, Kenneth J Sher et al.•Alcoholism: Clinical and…•2018

  Incluir item

• A time of change

  Open Access•Leah H Somerville, Rebecca M Jones et al.•Brain and Cognition•2010

  Incluir item

• Large-scale automated synthesis of human functional neuroimaging data

  Open Access•Tal Yarkoni, Russell A Poldrack et al.•Nature Methods•2011

  Incluir item

• Parenting Factors Associated with Reduced Adolescent Alcohol Use

  Open Access•Siobhan M Ryan, Anthony F Jorm et al.•Australian & New Zealand Journal…•2010

  Incluir item

• The Self-Medication Hypothesis of Substance Use Disorders

  Edward J Khantzian•Harvard Review of Psychiatry•1997

  Incluir item

• FSL

  Open Access•Mark Jenkinson, Christian F Beckmann et al.•NeuroImage•2012

  Incluir item

• The CES-D Scale

  Open Access•Lenore Sawyer Radloff•Applied Psychological Measurement•1977

  Incluir item

• Early Childhood Parenting Predicts Late Childhood Brain Functional Connectivity During Emotion Perception and Reward Processing

  Open Access•Daniel C Kopala-Sibley, Daniel C Kopala‐Sibley et al.•Child Development•2020

  Incluir item

• Baseline brain and behavioral factors distinguish adolescent substance initiators and non-initiators at follow-up

  Open Access•Goldie Ann Mcquaid, Valerie L Darcey et al.•Frontiers in Psychiatry•2022

  Incluir item

• A review of associations between parental emotion socialization behaviors and the neural substrates of emotional reactivity and regulation in youth

  Patricia Z Tan, Caroline W Oppenheimer et al.•Developmental Psychology•2020

  Incluir item

• The Role of the Family Context in the Development of Emotion Regulation

  Open Access•Amanda S Morris, Jennifer S Silk et al.•Social Development•2007

  Incluir item

• Relations of Temperament to Maladjustment and Ego Resiliency in At‐risk Children

  Open Access•Nancy Eisenberg, Rg Haugen et al.•Social Development•2009

  Incluir item

• Sex‐differentiated associations among negative parenting, emotion‐related brain function, and adolescent substance use and psychopathology symptoms

  Open Access•Tara M Chaplin, Jennifer A Poon et al.•Social Development•2019

  Incluir item

• The Development of Impulsivity and Sensation Seeking

  Open Access•Alexander M Wasserman, C W Mathias et al.•Journal of Research on Adolescence•2020

  Incluir item

• Chinese mothers’ parental burnout and adolescents’ internalizing and externalizing problems

  Bin-Bin Chen, Yang Qu et al.•Developmental Psychology•2022

  Incluir item

• A conceptual model for the development of externalizing behavior problems among kindergarten children of alcoholic families

  Rina D Eiden, Ellen P Edwards et al.•Developmental Psychology•2007

  Incluir item