The primate vaginal microbiome
Comparative context and implications for human health and disease
Dados Bibliográficos
The primate body hosts trillions of microbes. Interactions between primate hosts and these microbes profoundly affect primate physiology, reproduction, health, survival, and ultimately, evolution. It is increasingly clear that primate health cannot be understood fully without knowledge of host‐microbial interactions. Our goals here are to review what is known about microbiomes of the female reproductive tract and to explore several factors that influence variation within individuals, as well as within and between primate species. Much of our knowledge of microbial variation derives from studies of humans, and from microbes located in nonreproductive regions (e.g., the gut). We review work suggesting that the vaginal microbiota affects female health, fecundity, and pregnancy outcomes, demonstrating the selective potential for these agents. We explore the factors that correlate with microbial variation within species. Initial colonization by microbes depends on the manner of birth; most microbial variation is structured by estrogen levels that change with age (i.e., at puberty and menopause) and through the menstrual cycle. Microbial communities vary by location within the vagina and can depend on the sampling methods used (e.g., swab, lavage, or pap smear). Interindividual differences also exist, and while this variation is not completely understood, evidence points more to differences in estrogen levels, rather than differences in external physical environment. When comparing across species, reproductive‐age humans show distinct microbial communities, generally dominated by Lactobacillus , unlike other primates. We develop evolutionary hypotheses to explain the marked differences in microbial communities. While much remains to be done to test these hypotheses, we argue that the ample variation in primate mating and reproductive behavior offers excellent opportunities to evaluate host‐microbe coevolution and adaptation. Am J Phys Anthropol 57:119–134, 2013. © 2013 Wiley Periodicals, Inc
Bioinformatics · Biology · Context (archaeology) · Disease · Evolutionary biology · Fecundity · Microbiome · Population · Primate · Vagina · Zoology · Adolescent Sexual and Reproductive Health · Demography · Ecology · Genetics · Gut microbiota and health · Medicine · Physiology · Reproductive tract infections research
Relationships Between Estradiol Levels and Vaginal Lactobacillus Abundance Across the Menstrual Cycles in Women
Low Lactobacilli abundance and polymicrobial diversity in the lower reproductive tract of female rhesus monkeys do not compromise their reproductive success
Composition and stability of the vervet monkey milk microbiome
Influence of age, reproductive cycling status, and menstruation on the vaginal microbiome in baboons ( Papio anubis )
The importance of scale in comparative microbiome research
Ethical priority of the most actionable system of biomolecules
Microbial Contributions to Primate Reproduction
Infectious Diseases in Primates
Primate Sexuality
The diversity and biogeography of soil bacterial communities
Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
An obesity-associated gut microbiome with increased capacity for energy harvest
Birth, obstetrics and human evolution
Testis weight, body weight and breeding system in primates
Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions
Pathogens and the Evolution of Primate Sociality
Toward an Ecological Classification of Soil Bacteria
Long‐Term Effects of Logging on African Primate Communities
Human gut microbiome viewed across age and geography
The Human Microbiome Project
Baboon vaginal microbiota
Behavior patterns of Southern Bearded Sakis ( Chiropotes satanas ) in the fragmented landscape of Eastern Brazilian Amazonia
Differences between the normal vaginal bacterial community of baboons and that of humans
Sexual conflict in primates
Sexual selection in primates
Discrete dental trait asymmetry in Mexican and Belizean groups
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| Intervalo de citações | 2015 - 2026 (12) |
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| Tipos de citação | Neutras: 7 |